abstract：:I was asked to write this article to share with medical professionals, my view as a parent with a child who has special needs and needs a transplant. It is a detailed story from a parent's point of view on what it is like to have a child with special needs with serious medical complications and how I went about findin...

journal_title：Pediatric transplantation

authors： Carney MT

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:ILNEB constitute an autosomal recessive disorder caused by homozygous or compound heterozygous mutation of the gene for the ITGA3. To date, 8 ILNEB patients have been reported, but all 6 neonatal-onset ILNEB patients suffered early death within 2 years. The most common cause of death among previously reporte...

journal_title：Pediatric transplantation

authors： Okamoto T,Nakamura A,Hayashi A,Yamaguchi T,Ogawa Y,Natsuga K,Yanagi K,Hotta K

更新日期：2021-01-20 00:00:00

abstract：:Delayed recovery of thrombocytopenia is a well-known complication after allogeneic HSCT. Eltrombopag (ELT), a thrombopoietin receptor agonist (TRAs), induces platelet maturation and release. Mostly conducted in adults, some of the previous studies have shown that ELT seems to enhance platelet recovery for post-allogen...

journal_title：Pediatric transplantation

authors： Yaman Y,Elli M,Şahin Ş,Özdilli K,Bilgen H,Bayram N,Nepesov S,Anak S

更新日期：2021-01-16 00:00:00

abstract：BACKGROUND:Of the 600 pediatric candidates added to the liver waiting list annually, 100 will remain waiting while over 100 liver allografts are discarded, often for subjective reasons. METHODS:We created a risk index to predict discard to better optimize donor supply. We used the UNOS database to retrospectively anal...

journal_title：Pediatric transplantation

authors： Malik T,Joshi M,Godfrey E,Galvan T,O'Mahony CA,Cotton R,Goss J,Rana A

更新日期：2021-01-06 00:00:00

abstract：:Ascending aortic pseudoaneurysm is a rare complication after HT. Surgery is the most conventional management, but in some patients, it is risky. We report the case of a ten-year-old child who underwent HT and developed an ascending aortic pseudoaneurysm in the aortic anastomosis. He was successfully treated with two c...

journal_title：Pediatric transplantation

authors： Skrabonja-Crespo A,Chavarri-Velarde F,Pinto-Salinas M,Tauma-Arrué A

更新日期：2020-12-17 00:00:00

abstract：BACKGROUND:Urinary diversion using catheterizable channel among posterior urethral valve (PUV) patients may help to alleviate the functional concerns of the bladder on the allograft. Herein, we review our series of PUV patients undergoing renal transplants at a single institution to determine outcomes between those wit...

journal_title：Pediatric transplantation

authors： Rickard M,Chua ME,Zu'bi F,Dos Santos J,Koyle MA,Lorenzo AJ,Farhat WA

更新日期：2020-12-01 00:00:00

abstract：:Patients with defects in the ATP6AP1 gene have rarely been described. ATP6AP1-related disorders are a subtype of CDG, which result in enzyme deficiencies affecting multiple organ systems ranging from mild to life-threatening. Of the 13 patients described, all had hepatopathy, but this is the first case to be successfu...

journal_title：Pediatric transplantation

authors： Gumm AJ,Basel DG,Thakrar P,Suchi M,Telega G

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:No previous paediatric study has evaluated the frequency of diagnostic disagreement between clinical standard histopathological assessment (CSHA) and retrospective, independent, histopathological assessment (RIHA) of gastrointestinal Graft-Versus-Host Disease (GI-GVHD) METHODS: In a retrospective cohort stud...

journal_title：Pediatric transplantation

authors： Mårtensson T,Szakos A,Mellgren K,Toporski J,Arvidson J,Mattsson J,Gustafsson B,Casswall TH

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Cryptosporidium enteritis can be devastating in the immunocompromised host. In pediatric liver transplant recipients, infection may be complicated by prolonged carriage of the parasite, rejection, and biliary tree damage and fibrosis. Herein, we report on six patients and their long-term outcomes following c...

journal_title：Pediatric transplantation

authors： Fischer RT,Day JC,Wasserkrug H,Faseler M,Kats A,Daniel JF,Slowik V,Andrews W,Hendrickson RJ

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:In adults, the time of day for LT does not affect post-transplant outcomes. Whether this is true or not in children is unknown. In this study, we aimed to evaluate if weekend and weeknight liver transplants are associated with worse patient and graft survival in children. METHODS:We interrogated the UNOS da...

journal_title：Pediatric transplantation

authors： Rogers ME,Egberg MD,Sylvester F,Lichtman S,Lin FC

更新日期：2020-12-01 00:00:00

abstract：:aHUS is caused by the over-activation and dysregulation of the alternative complement pathway. Data regarding outcomes of pediatric aHUS patients after kidney transplantation are still very scarce. Accordingly, the aim of this study was to describe the clinical findings and outcomes of pediatric aHUS patients after re...

journal_title：Pediatric transplantation

authors： Özçakar ZB,Ozaltin F,Gülhan B,Çomak E,Parmaksız G,Baskın E,Topaloğlu R,Kasap Demir B,Canpolat N,Yuruk Yildirim Z,Demircioğlu Kılıç B,Yüksel S,Söylemezoğlu O

更新日期：2020-11-20 00:00:00

abstract：:Ingestion of rare-earth magnet beads in children has been a public health concern. The potential risk of swallowing multiple magnets is related to magnet attraction to each other, resulting in serious gastrointestinal complications, such as entero-enteric fistula formation, peritonitis, bowel ischemia or necrosis, bow...

journal_title：Pediatric transplantation

authors： Miri A,Nakayuenyongsuk W,Vargas L,Langnas A,Vo HD

更新日期：2020-11-20 00:00:00

abstract：:UCBT recipients with TM are at high risk of EF related to low number of stem cells and prior alloimmunization after multiple blood transfusions. Here, we evaluated the safety and efficacy of double-unit UCBT using TT-containing conditioning regimens in TM. Retrospective analysis of children who underwent double-unit U...

journal_title：Pediatric transplantation

authors： Feng J,Lee V,Leung AWK,Lam GKS,Chow TTW,Cheng FWT,Yan CLS,Lee CK,Yuen PMP,Li CK

更新日期：2020-11-02 00:00:00

abstract：:LT is a successful treatment for end-stage liver disease. The long-term outcome of patients transplanted in childhood has not previously been widely reported. This project assessed the long-term impact of transplantation in patients surviving >15 years. Retrospective data on growth, end-organ damage and psychosocial d...

journal_title：Pediatric transplantation

authors： Ruth N,Sharif K,Legarda M,Smith M,Lewis P,Lloyd C,Mirza D,Kelly D

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Self-management for patients who have undergone solid organ transplantation is demanding and a challenge for adolescents transitioning into adult-oriented healthcare systems. This study explores whether adolescent and young adult solid organ transplant patients support the use of online peer support programs ...

journal_title：Pediatric transplantation

authors： Anthony SJ,Young K,Ghent E,Gold A,Martin K,Solomon M,Teoh CW,Stinson J

更新日期：2020-11-01 00:00:00

abstract：:Although it is known that children undergoing heart transplantation are at increased risk for both AKI and CKD, renal function following CHLT remains understudied. All pediatric CHLT patients from 2006 to 2019 were included. The prevalence of AKI in the first 7 post-operative days, renal recovery at 30 post-operative ...

journal_title：Pediatric transplantation

authors： Lee A,Concepcion W,Gonzales S,Sutherland SM,Hollander SA

更新日期：2020-11-01 00:00:00

abstract：:eHAT is one of the most dreaded post-LT complication. Treatment approaches include retransplantation, revascularization, or observation. Systemic thrombolytic therapy is used in pediatric patients with thromboembolic events. However, there is no previous study reporting on the use of systemic r-tPA to treat eHAT. The ...

journal_title：Pediatric transplantation

authors： Feier FH,Melere MU,Trein CS,da Silva CS,Lucchese A,Horbe A,Tonet F,Ricachinevsky C,Ferreira CT,Chedid MF,Kalil AN

更新日期：2020-10-27 00:00:00

abstract：:Alternate donor HSCT for thalassemia major from a matched unrelated donor or haploidentical family donor is a feasible therapeutic option in children with no matched family donor. Aggressive pretransplant immunosuppression, reduced toxicity conditioning, and PTCY result in excellent thalassemia-free survival. We descr...

journal_title：Pediatric transplantation

authors： Vellaichamy Swaminathan V,Ravichandran N,Ramanan KM,Meena SK,Varla H,Ramakrishnan B,Jayakumar I,Uppuluri R,Raj R

更新日期：2020-10-27 00:00:00

abstract：BACKGROUND:Scientific advancements are occurring in cardiac xenotransplantation (XTx). However, there have been religious and social concerns surrounding this allotransplantation alternative. The purpose of this study was to explore the acceptance of XTx among stakeholders of the congenital heart disease (CHD) communit...

journal_title：Pediatric transplantation

authors： Padilla LA,Rhodes L,Sorabella RA,Hurst DJ,Cleveland DC,Dabal RJ,Cooper DK,Paris W,Carlo WF

更新日期：2020-10-06 00:00:00

abstract：:Much is still unknown about LUT function after receiving renal graft. Graft function was the main focus of different studies discussing the same issue. However, these studies ignored the effects of the graft on lower tract function and more demand for bladder cycling and growth of the child. Therefore, we aimed at eva...

journal_title：Pediatric transplantation

authors： Aboulela W,Fawzy AM,Abdelmawla MA,Salah DM,Eldin MS,Mohamed Anwar AZ,El Ghoneimy M,Shouman AM,Shoukry AI,Bazaraa H,Tawfiek ER,Fadel F,Badawy H,Morsi HA,Ghoneima W

更新日期：2020-09-01 00:00:00

abstract：:Deficiency of the CD40L, expressed on the surface of T lymphocytes, is caused by mutations in the glycoprotein CD40L (CD154) gene. Resulting defective humoral and cellular responses cause a clinical presentation that includes recurrent sinopulmonary bacterial infections, opportunistic infections, sclerosing cholangiti...

journal_title：Pediatric transplantation

authors： Uygun DFK,Uygun V,Karasu GT,Daloğlu H,Öztürkmen SI,Çelmeli F,Törün SH,Özen A,Barış S,Aydıner EK,Yalçın K,Kılıç SÇ,Hazar V,Bingöl A,Yeşilipek A

更新日期：2020-09-01 00:00:00

abstract：:TB is an increasing health problem, and patients undergoing HSCT are more prone to develop tuberculosis. The aim of our study was to evaluate prevalence of latent tuberculosis in HSCT recipients. In this study, 84 patients (2 months to 18 years) who were candidates for HSCT at the referral hospital of Tehran Children'...

journal_title：Pediatric transplantation

authors： Mahmoudi S,Pourakbari B,Sadeghi RH,Hamidieh AA,Safari Sharari A,Salajegheh P,Aziz-Ahari A,Mamishi S

更新日期：2020-09-01 00:00:00

abstract：:De novo PTAID may develop in pediatric solid organ transplant recipients, have a diverse spectrum, and are occasionally treatment resistant. Previous reports showed resolution of immune cytopenias in solid organ transplant recipients following replacement of the calcineurin inhibitor tacrolimus with the mTOR inhibitor...

journal_title：Pediatric transplantation

authors： Kehar M,Grunebaum E,Jimenez-Rivera C,Mozer-Glassberg Y,Jamal A,Ng VL,Avitzur Y

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND/AIM:Several PK studies have shown that most pediatric patients may require higher doses on a mg/kg basis compared to adults to attain similar therapeutic trough concentrations. The aim of this study was to compare the efficacy and safety of three times daily to twice a day dosing of tacrolimus in pediatric k...

journal_title：Pediatric transplantation

authors： Alabdulkarim Z,Al-Jedai A,Alkortas D,Alhasan K,Devol E

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:Myeloablative conditioning before allogeneic HSCT during childhood exposes to serious long-term complications, especially gonadal dysfunction. Pubertal issues are less described than other post-HSCT sequelae in childhood. METHODS:Pubertal development and biological gonadal parameters were assessed in a re...

journal_title：Pediatric transplantation

authors： Weinhard S,Wiedemann A,Leheup B,Dalle JH,Lebon Labich B,Pochon C

更新日期：2020-09-01 00:00:00

abstract：:PPCA has historically been considered detrimental to donor quality in LT, but transplantation of grafts from this group of donors is now routine. Our study aims to evaluate the outcomes associated with use of donors with a history of PPCA in the pediatric population. This study is a single-center retrospective analysi...

journal_title：Pediatric transplantation

authors： Schroering JR,Hathaway TJ,Kubal CA,Ekser B,Mihaylov P,Mangus RS

更新日期：2020-08-01 00:00:00

abstract：:Studies are increasingly recognizing health-related quality of life (HRQOL) as a key pediatric outcome in both clinical and research settings and an essential health outcome measure to assess the effectiveness of medical treatment. However, it has not yet been studied among the healthy siblings of kidney transplant re...

journal_title：Pediatric transplantation

authors： Velasco J,Ferraris JR,Eymann A,Ghezzi LFR,Coccia PA,Ferraris V

更新日期：2020-08-01 00:00:00

abstract：:Live viral vaccines have historically been avoided in children after solid organ transplantation. Multiple reports of safety and immunogenicity, largely in the pediatric liver transplant population, have led to a reconsideration of this recommendation. Here, we report the case of a 4-year-old boy who inadvertently rec...

journal_title：Pediatric transplantation

authors： Bobrowski AE,Muller WJ

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:The optimal conditioning regimen for alloHCT in children with myeloid malignancies remains undefined. PROCEDURE:We performed a retrospective review of children undergoing alloHCT for AML and MDS over a 10-year period (2008-2018) at our institution, comparing the outcomes of recipients of either a myeloablat...

journal_title：Pediatric transplantation

authors： Oshrine B,Adams L,Nguyen ATH,Amankwah E,Shyr D,Hale G,Petrovic A

更新日期：2020-06-01 00:00:00

abstract：:We examined SCC development of 24 FA patients, who received HSCT from HLA-matched relatives. In our BMT center, we applied low-dose CY + LFI + ATG (n:13) as conditioning regimen for FA patients between 1992 and 1999, and CY + BU + ATG (n:11) between 1999 and 2002. The aim of this study was to investigate SCC developme...

journal_title：Pediatric transplantation

authors： Anak S,Yalman N,Bilgen H,Sepet E,Deviren A,Gürtekin B,Tunca F,Başaran B

更新日期：2020-06-01 00:00:00

abstract：:This prospective observational study analyzed the pharmacokinetics of busulfan in Japanese children and evaluated the predicting accuracy of previous pediatric PPK models of busulfan. This study enrolled five patients (aged 2-12 years, BW 14-48 kg) receiving a busulfan-based conditioning regimen for hematopoietic stem...

journal_title：Pediatric transplantation

authors： Kishimoto K,Hasegawa D,Irie K,Okada A,Nakamura S,Tamura A,Yamamoto N,Kozaki A,Saito A,Ishida T,Fukushima S,Kosaka Y

更新日期：2020-06-01 00:00:00

abstract：:Nephrotic syndrome is characterized by proteinuria, hypoalbuminemia, and general edema. These symptoms may persist in children who reach ESRD, which is unfavorable for the patient's allograft outcome. In addition, this may hamper early diagnosis of a relapse after transplantation. Surgical bilateral nephrectomy is oft...

journal_title：Pediatric transplantation

authors： Vos E,Koster-Kamphuis L,van de Kar NCAJ,Bootsma-Robroeks CMHHT,Cornelissen EAM,Schreuder MF

更新日期：2020-06-01 00:00:00

abstract：:With the number of long-term HSCT survivors steadily increasing, attention needs to be focused on the late complications and quality of life. We therefore analyzed the outcome of 101 pediatric patients (<18 years old at the time of HSCT) transplanted for acute leukemia between 1981 and 2015 at Complexo Hospital de Clí...

journal_title：Pediatric transplantation

authors： Marinho DH,Ribeiro LL,Nichele S,Loth G,Koliski A,Mousquer RTG,Funke VAM,Page K,Fasth A,Pasquini R,Boguszewski MCDS,Bonfim C

更新日期：2020-06-01 00:00:00

abstract：:HTN after renal transplantation is associated with cardiovascular morbidity. ABPM allows diagnosis of masked HTN and isolated nocturnal HTN. Longitudinal ABPM data in children post-transplant are limited. ABPM was performed in children post-transplant and repeated in 6-12 months. BP indices were used to determine the ...

journal_title：Pediatric transplantation

authors： Pais P,Dello Strologo L,Iyengar A,Velusamy V,Greenbaum LA

更新日期：2020-06-01 00:00:00

abstract：:With small kidneys, EBKTs could provide sufficient renal mass but could lead to inefficient use of resources, while SKTs could result in insufficient function due to small renal mass. We aimed to compare the outcomes of EBKT and SKT from small donors weighing ≤15 kg to pediatric recipients. We retrospectively reviewed...

journal_title：Pediatric transplantation

authors： Mo H,Ko H,Chung CTY,Kim HK,Han A,Min S,Ha J

更新日期：2020-05-06 00:00:00

abstract：:Abdominal wall closure after pediatric liver transplantation (pLT) in infants may be hampered by graft-to-recipient size discrepancy. Herein, we describe the use of a porcine dermal collagen acellular graft (PDCG) as a biological mesh (BM) for abdominal wall closure in pLT recipients. Patients <2 years of age, who und...

journal_title：Pediatric transplantation

authors： Gül-Klein S,Dziodzio T,Martin F,Kästner A,Witzel C,Globke B,Jara M,Ritschl PV,Henning S,Gratopp A,Bufler P,Schöning W,Schmelzle M,Pratschke J,Öllinger R

更新日期：2020-05-01 00:00:00

abstract：:The high discard rate of pediatric donor hearts presents a major challenge for children awaiting heart transplantation. Recent literature identifies several factors that contribute to the disparities in pediatric donor heart usage, including regulatory oversight, the absence of guidelines on pediatric donor heart acce...

journal_title：Pediatric transplantation

authors： Butler A,Chapman G,Johnson JN,Amodeo A,Böhmer J,Camino M,Davies RR,Dipchand AI,Godown J,Miera O,Pérez-Blanco A,Rosenthal DN,Zangwill S,Kirk R

更新日期：2020-05-01 00:00:00

abstract：:Cardiac transplantation for children with end-stage cardiac disease with no other medical or surgical options is now standard. The number of children in need of cardiac transplant continues to exceed the number of donors considered "acceptable." Therefore, there is an urgent need to understand which recipients are in ...

journal_title：Pediatric transplantation

authors： Denfield SW,Azeka E,Das B,Garcia-Guereta L,Irving C,Kemna M,Reinhardt Z,Thul J,Dipchand AI,Kirk R,Davies RR,Miera O

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Pediatric heart-lung transplantation (HLT) is rare, and no report has analyzed patient outcomes since time of listing. We analyzed pediatric HLTs to understand risk factors for waitlist and post-HLT mortality. METHODS:All pediatric (<18 year old) HLT candidates were identified within the UNOS database (n = ...

journal_title：Pediatric transplantation

authors： Riggs KW,Chapman JL,Schecter M,Towe C,Zafar F,Morales DLS

更新日期：2020-05-01 00:00:00

abstract：:Children receiving HCT loose protective immunity to vaccines received pre-HCT. Therefore, revaccination post-HCT is of major importance. In Denmark, a vaccination schedule with fewer doses post-HCT has been used, including two doses for diphtheria, tetanus, polio, measles, mumps, and rubella, and one dose only for Hae...

journal_title：Pediatric transplantation

authors： Jensen L,Poulsen A,Nygaard U,Scheike T,Riis MS,Pedersen FK,Heilmann C

更新日期：2020-02-01 00:00:00