Varicella infection following vaccination in a pediatric kidney transplant recipient.

Abstract:

:Live viral vaccines have historically been avoided in children after solid organ transplantation. Multiple reports of safety and immunogenicity, largely in the pediatric liver transplant population, have led to a reconsideration of this recommendation. Here, we report the case of a 4-year-old boy who inadvertently received the live attenuated MMR-varicella vaccine (MMRV) at a routine well-child visit 16 months after receiving a living donor kidney transplant. This was not known until after he was admitted with rash and documented disseminated varicella infection 5 weeks later. He was treated with intravenous acyclovir followed by oral therapy and recovered fully. This case and its discussion illustrate what is still unknown about the risk-to-benefit ratio of live viral vaccination in any individual transplant recipient. Criteria to determine which patients should receive these vaccines should be evaluated before their use after transplant becomes routine, and all recipients and their families should be counseled to have a low threshold to seek medical care for any febrile illness or rash after live viral vaccination.

journal_name

Pediatr Transplant

authors

Bobrowski AE,Muller WJ

doi

10.1111/petr.13667

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

e13667

issue

4

eissn

1397-3142

issn

1399-3046

journal_volume

24

pub_type

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    journal_title:Pediatric transplantation

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    authors: Ali SR,Shaheen I,Young D,Ramage I,Maxwell H,Hughes DA,Athavale D,Shaikh MG

    更新日期:2018-03-01 00:00:00

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    abstract:BACKGROUND:With an increasing number of heart transplantations (HTx) performed in children and an extended long-term survival of these patients, the importance of transplant coronary artery disease (TCAD) rises in this group of transplant recipients. Reliable serum markers for diagnosis or non-invasive monitoring of th...

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    authors: Hilgendorff A,Kraemer U,Afsharian M,Bauer J,Tillmanns H,Kemkes-Matthes B,Kreuder J,Hoelschermann H

    更新日期:2006-06-01 00:00:00

  • Unexpectedly high prevalence of pretransplant abnormal glucose tolerance in pediatric kidney transplant recipients.

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    journal_title:Pediatric transplantation

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    authors: Shishido S,Sato H,Asanuma H,Shindo M,Hataya H,Ishikura K,Hamasaki Y,Goto M,Ikeda M,Honda M

    更新日期:2006-02-01 00:00:00

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    journal_title:Pediatric transplantation

    pub_type: 杂志文章

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    authors: DiFusco LA,Saylor JL,Schell KA

    更新日期:2020-02-01 00:00:00

  • Serial signal-averaged electrocardiography in children after cardiac transplantation.

    abstract::In patients with myocytolysis detected in endomyocardial biopsy, there is a tendency towards a shift of ventricular electrical axes from normal to strain pattern on surface ECG. Their 12-lead signal-averaged electrocardiogram (SAECG) show a significant increase in filtered QRS duration (QRSD) compared with those with ...

    journal_title:Pediatric transplantation

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    authors: Bennhagen RG,Sörnmo L,Pahlm O,Pesonen E

    更新日期:2005-12-01 00:00:00

  • Outpatient pediatric renal transplant biopsy--is it safe?

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    journal_title:Pediatric transplantation

    pub_type: 杂志文章

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    authors: Sweeney C,Geary DF,Hebert D,Robinson L,Langlois V

    更新日期:2006-03-01 00:00:00

  • Vesico-ureteral reflux in pediatric kidney transplants: clinical relevance to graft and patient outcome.

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    journal_title:Pediatric transplantation

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    更新日期:1999-08-01 00:00:00

  • Unrelated donor cord blood transplantation for non-malignant disorders in children and adolescents.

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    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.12213

    authors: Park M,Lee YH,Kang HR,Lee JW,Kang HJ,Park KD,Shin HY,Ahn HS,Baek HJ,Kook H,Hwang TJ,Lee JW,Chung NG,Cho B,Kim HK,Lee SH,Yoo KH,Sung KW,Koo HH,Koh KN,Im HJ,Seo JJ,Park JE,Lim YJ,Lyu CJ,Lee JM,Hah JO,K

    更新日期:2014-03-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2001-08-01 00:00:00

  • The use of a Berlin Heart EXCOR LVAD in a child receiving chemotherapy for Castleman's disease.

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    更新日期:2015-02-01 00:00:00

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    authors: Chen Y,Huang XJ,Liu KY,Chen H,Chen YH,Zhang XH,Wang FR,Han W,Wang JZ,Wang Y,Yan CH,Zhang YY,Sun YQ,Xu LP

    更新日期:2015-12-01 00:00:00

  • Minimum mycophenolic acid levels are associated with donor-specific antibody formation.

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    journal_title:Pediatric transplantation

    pub_type: 杂志文章

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    更新日期:2016-05-01 00:00:00

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    更新日期:2007-12-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2010-08-01 00:00:00

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    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.12138

    authors: Vidyadharan R,van Bommel AC,Kuti K,Gupte GL,Sharif K,Richard BM

    更新日期:2013-11-01 00:00:00

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    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.13733

    authors: Alabdulkarim Z,Al-Jedai A,Alkortas D,Alhasan K,Devol E

    更新日期:2020-09-01 00:00:00

  • Transmission of clear cell tumor in a graft liver from cadaveric donor: case report.

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    journal_title:Pediatric transplantation

    pub_type: 杂志文章,评审

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    authors: Backes AN,Tannuri AC,de Mello ES,Gibelli NE,de Castro Andrade W,Tannuri U

    更新日期:2012-12-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1111/petr.13683

    authors: Gül-Klein S,Dziodzio T,Martin F,Kästner A,Witzel C,Globke B,Jara M,Ritschl PV,Henning S,Gratopp A,Bufler P,Schöning W,Schmelzle M,Pratschke J,Öllinger R

    更新日期:2020-05-01 00:00:00

  • Psychopathology, quality of life, and related factors in pediatric liver transplantation candidates and recipients.

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    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.13633

    authors: Ünay M,Önder A,Gizli Çoban Ö,Atalay A,Sürer Adanir A,Artan R,Özatalay E

    更新日期:2020-02-01 00:00:00

  • Percutaneous endovascular management of ascending aortic pseudoaneurysm after heart transplantation in a pediatric patient.

    abstract::Ascending aortic pseudoaneurysm is a rare complication after HT. Surgery is the most conventional management, but in some patients, it is risky. We report the case of a ten-year-old child who underwent HT and developed an ascending aortic pseudoaneurysm in the aortic anastomosis. He was successfully treated with two c...

    journal_title:Pediatric transplantation

    pub_type:

    doi:10.1111/petr.13958

    authors: Skrabonja-Crespo A,Chavarri-Velarde F,Pinto-Salinas M,Tauma-Arrué A

    更新日期:2020-12-17 00:00:00

  • Collecting duct carcinoma arising in association with BK nephropathy post-transplantation in a pediatric patient. A case report with immunohistochemical and in situ hybridization study.

    abstract::The development of malignancy in a renal transplant graft is an uncommon phenomenon. A renal neoplasm developing in the adult donor kidney of a pediatric transplant recipient has only rarely been reported. We report a case of collecting duct carcinoma arising in association with BK virus nephropathy in an adult living...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-3046.2007.00855.x

    authors: Emerson LL,Carney HM,Layfield LJ,Sherbotie JR

    更新日期:2008-08-01 00:00:00

  • The SPLIT research agenda 2013.

    abstract::This review focuses on active clinical research in pediatric liver transplantation with special emphasis on areas that could benefit from studies utilizing the SPLIT infrastructure and data repository. Ideas were solicited by members of the SPLIT Research Committee and sections were drafted by members of the committee...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/petr.12090

    authors: Alonso EM,Ng VL,Anand R,Anderson CD,Ekong UD,Fredericks EM,Furuya KN,Gupta NA,Lerret SM,Sundaram S,Tiao G,Studies of Pediatric Liver Transplantation (SPLIT) Research Group.

    更新日期:2013-08-01 00:00:00

  • De novo development of antibodies to kidney-associated self-antigens angiotensin II receptor type I, collagen IV, and fibronectin occurs at early time points after kidney transplantation in children.

    abstract::Chronic rejection is the leading cause of graft loss following pediatric kidney transplantation. Our group and others have demonstrated an association between the development of Abs to self-antigens and chronic rejection following adult lung and heart transplantation. The goal of this study was to determine whether Ab...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.12531

    authors: Hesemann LE,Subramanian V,Mohanakumar T,Dharnidharka VR

    更新日期:2015-08-01 00:00:00

  • Severe cryptosporidiosis in a seven-year-old renal transplant recipient: case report and review of the literature.

    abstract::Cryptosporidium is an intracellular protozoa that can cause gastroenteritis in humans. In immunocompromised hosts, infection can be severe, leading to life-threatening persistent diarrhea. There is limited experience in treating this infection in solid organ transplants. Although newer drugs active against Cryptospori...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/j.1399-3046.2006.00593.x

    authors: Hong DK,Wong CJ,Gutierrez K

    更新日期:2007-02-01 00:00:00

  • Impact of pretransplant minimal residual disease on the post-transplant outcome of pediatric acute lymphoblastic leukemia.

    abstract::There are few reports on the clinical significance of MRD before HSCT in pediatric ALL. We retrospectively analyzed the clinical significance of FCM-based detection of MRD (FCM-MRD) before allogeneic HSCT in pediatric ALL. Of 38 pediatric patients who underwent allogeneic HSCT for the first time between 1998 and 2014,...

    journal_title:Pediatric transplantation

    pub_type: 杂志文章

    doi:10.1111/petr.12732

    authors: Umeda K,Hiramatsu H,Kawaguchi K,Iwai A,Mikami M,Nodomi S,Saida S,Heike T,Ohomori K,Adachi S

    更新日期:2016-08-01 00:00:00