Pubertal outcomes of children transplanted with allogeneic stem cells after myeloablative total body irradiation or busulfan: Influence of age and sex is confirmed, while a role of chronic graft-versus-host disease in delayed puberty onset is revealed.

abstract：:This study reports the clinical complication and infection rates of an active pediatric IT program that has never utilized bowel decontamination in either the donor or the recipient. All patients undergoing IT from 2003 to 2015 at a single pediatric IT center were reviewed. Post-transplant surgical, infectious, and im...

journal_title：Pediatric transplantation

authors： Clouse JW,Kubal CA,Fridell JA,Mangus RS

更新日期：2018-05-01 00:00:00

abstract：:BM remains an important source of stem cells. The BM characteristics change with age but the estimation of CD34 calculation of one CD34+ cell per 100 nucleated cells is used for all donors including pediatric donors in the operating room before getting the actual CD34 count. In order to see whether this formula is app...

journal_title：Pediatric transplantation

authors： Ince EU,Ileri T,Dogu F,Ates C,Cakmakli H,Dalva K,Ikinciogullari A,Uysal Z,Ertem M

更新日期：2015-06-01 00:00:00

abstract：:Recurrent and de novo disease is an increasing problem and is known to negatively impact transplant graft survival. Immunosuppressive medications have not had an impact on the prevalence of recurrent and de novo disease. Renal Allograft Disease Registry (RADR) was established to study the prevalence, impact and risk f...

journal_title：Pediatric transplantation

authors： Hariharan S,Savin VJ

更新日期：2004-08-01 00:00:00

abstract：:There is a shortage of pediatric donor hearts for waitlisted children, and yet nearly 50% of organs offered are not transplanted. Donor quality is often cited as a reason for declining organs offered from donors infected with influenza, presumably due to concern about disease transmission at transplant leading to seve...

journal_title：Pediatric transplantation

authors： Smith CJ,McCulloch MD,Shirley DA,L'Ecuyer TJ

更新日期：2019-12-01 00:00:00

abstract：:Historically inability to achieve portal inflow to the liver allograft operatively was felt to be a contraindication to orthotopic liver transplantation (OLTx). Cavoportal hemi transposition has been utilized more recently in adult OLTx recipients but rarely in pediatric recipients. Here we report the case of a 10-mon...

journal_title：Pediatric transplantation

authors： Verran D,Crawford M,Stormon M,Shun A

更新日期：2004-08-01 00:00:00

abstract：:In order to assess certain aspects of pediatric kidney transplantation (Tx) in Turkey, we retrospectively analyzed the results of 56 of these pediatric procedures performed at our center. From January 1986 to January 1998, 56 pediatric renal Tx (29 males, 27 females; 0-17 yr of age) were carried out at Başkent Univers...

journal_title：Pediatric transplantation

authors： Haberal M,Bereket G,Karakayali H,Arslan G,Moray G,Bilgin N

更新日期：2000-11-01 00:00:00

abstract：:Vitamin C deficiency in developed countries is typically observed in patients with unique clinical conditions such as cystic fibrosis or anorexia nervosa, or in patients on long-term tube feeds. We report here a clinical observation in six pediatric and adolescent patients (median age 17.5 yr, range 9.8-23.5 yr) with ...

journal_title：Pediatric transplantation

authors： Kletzel M,Powers K,Hayes M

更新日期：2014-08-01 00:00:00

abstract：:We report a case of a patient who received a bilateral lung transplant for end-stage lung disease secondary to Gauchers type-1 disease with no evidence of recurrence of the disease in the transplanted lung. ...

journal_title：Pediatric transplantation

authors： Rao AR,Parakininkas D,Hintermeyer M,Segura AD,Rice TB

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:The optimal conditioning regimen for alloHCT in children with myeloid malignancies remains undefined. PROCEDURE:We performed a retrospective review of children undergoing alloHCT for AML and MDS over a 10-year period (2008-2018) at our institution, comparing the outcomes of recipients of either a myeloablat...

journal_title：Pediatric transplantation

authors： Oshrine B,Adams L,Nguyen ATH,Amankwah E,Shyr D,Hale G,Petrovic A

更新日期：2020-06-01 00:00:00

abstract：:We retrospectively analyzed the effects of recombinant human growth hormone (rhGH) in a Belgian population of 36 short children with renal allografts. Seven children were dropped from the growth study: 1 had skeletal dysplasia and in 6 cases rhGH was given for less than 1 yr (1 died, 1 developed genu valgum, 2 were no...

journal_title：Pediatric transplantation

authors： Janssen F,Van Damme-Lombaerts R,Van Dyck M,Hall M,Schurmans T,Herman J,Hooghe L,Van Damme B

更新日期：1997-11-01 00:00:00

abstract：:PMF of infancy is a recently described autosomal recessive disorder presenting with severe bone marrow failure, accelerated neutrophil apoptosis, and significant platelet dysfunction, caused by a mutation in the VPS45 gene. In this study, we update our group of patients with PMF, highlighting different aspects of this...

journal_title：Pediatric transplantation

authors： Stepensky P,Simanovsky N,Averbuch D,Gross M,Yanir A,Mevorach D,Elpeleg O,Weintraub M

更新日期：2013-12-01 00:00:00

abstract：:Primary graft dysfunction following HTx is associated with significant morbidity and mortality. This study aimed to assess the incidence of, risk factors for, and outcomes of children requiring ECMO within 24 hours of HTx. This study utilized a linked PHIS/SRTR database of pediatric HTx recipients (2002-2016). Post-HT...

journal_title：Pediatric transplantation

authors： Godown J,Bearl DW,Thurm C,Hall M,Feingold B,Soslow JH,Mettler BA,Smith AH,Profita EL,Singh TP,Dodd DA

更新日期：2019-06-01 00:00:00

abstract：:In patients with myocytolysis detected in endomyocardial biopsy, there is a tendency towards a shift of ventricular electrical axes from normal to strain pattern on surface ECG. Their 12-lead signal-averaged electrocardiogram (SAECG) show a significant increase in filtered QRS duration (QRSD) compared with those with ...

journal_title：Pediatric transplantation

authors： Bennhagen RG,Sörnmo L,Pahlm O,Pesonen E

更新日期：2005-12-01 00:00:00

abstract：:PBSCs have become the preferred source of autologous stem cells for supporting high-dose chemotherapy in childhood solid tumors. The aims of this retrospective study were to examine the optimal timing for administration of G-CSF after chemotherapy and to identify the patients from whom an optimal dose of PBSCs can be ...

journal_title：Pediatric transplantation

authors： Takahashi H,Kato M,Kikuchi A,Hanada R,Koh K

更新日期：2013-11-01 00:00:00

abstract：:Patients with defects in the ATP6AP1 gene have rarely been described. ATP6AP1-related disorders are a subtype of CDG, which result in enzyme deficiencies affecting multiple organ systems ranging from mild to life-threatening. Of the 13 patients described, all had hepatopathy, but this is the first case to be successfu...

journal_title：Pediatric transplantation

authors： Gumm AJ,Basel DG,Thakrar P,Suchi M,Telega G

更新日期：2020-12-01 00:00:00

abstract：:Diaphragmatic hernia after OLT is a rare surgical complication. We here report successful diagnosis and treatment of two cases with right-sided diaphragmatic hernia developed after OLT both utilizing left-sided allografts. Combination of factors related to the surgical techniques and patient characteristics might expl...

journal_title：Pediatric transplantation

authors： Kazimi M,Ibis C,Alper I,Ulas M,Baran M,Arikan C,Aydogdu S,Ulukaya S,Zeytunlu M,Kilic M

更新日期：2010-08-01 00:00:00

abstract：:The need for evidence-based practice guidelines requires high quality, carefully controlled clinical research trials. This multidisciplinary conference attempted to: identify urgent clinical and research issues, identify obstacles to performing clinical trials, develop concepts for organ-specific and all-organ researc...

journal_title：Pediatric transplantation

authors： Bartosh SM,Ryckman FC,Shaddy R,Michaels MG,Platt JL,Sweet SC

更新日期：2008-03-01 00:00:00

abstract：:Prematurity and very low birthweight have often been considered relative contraindications to neonatal organ donation. Organ procurement from neonatal donors is further complicated by unclear guidelines regarding neonatal brain death. We report a successful case of multivisceral transplantation using a graft from a 10...

journal_title：Pediatric transplantation

authors： Cauley RP,Suh MY,Kamin DS,Lillehei CW,Jenkins RL,Jonas MM,Vakili K,Kim HB

更新日期：2012-12-01 00:00:00

abstract：:We report a case of EBV encephalitis in a seven-yr-old child with Ph+ ALL. Two months after an allogeneic HSCT from his HLA mismatched mother, the patient showed an altered sensorium, generalized seizures, and a left hemiparesis. Brain MRI demonstrated multiple lesions highly suggestive for viral encephalitis. Blood a...

journal_title：Pediatric transplantation

authors： Barberi W,Perrone S,Iori AP,Torelli GF,Testi AM,Moleti ML,Ceglie T,Papoff P,Caresta E,Antonelli M,Gianno F,Melone A,Badiali M,Giangaspero F,Foà R,Gentile G

更新日期：2015-02-01 00:00:00

abstract：:LT is a successful treatment for end-stage liver disease. The long-term outcome of patients transplanted in childhood has not previously been widely reported. This project assessed the long-term impact of transplantation in patients surviving >15 years. Retrospective data on growth, end-organ damage and psychosocial d...

journal_title：Pediatric transplantation

authors： Ruth N,Sharif K,Legarda M,Smith M,Lewis P,Lloyd C,Mirza D,Kelly D

更新日期：2020-11-01 00:00:00

abstract：:Adults, older children, and adolescent patients with a BMI categorized as overweight or obese have decreased survival after HTx. Anthropometric correlates of survival after HTx in infants have not been well defined. In a retrospective analysis of the UNOS registry, patients age 0-24 months were classified according to...

journal_title：Pediatric transplantation

authors： McKee C,Tumin D,Hayes D Jr,Tobias JD

更新日期：2016-12-01 00:00:00

abstract：:Recipient lymphocytes are crucial for direct and indirect pathways of allorecognition. We proposed that the administration of alemtuzumab several weeks pretransplantation could eradicate peripheral lymphatic cells and promote donor-specific acceptance. This was a single-center, retrospective review of 101 consecutive ...

journal_title：Pediatric transplantation

authors： Kaabak MM,Babenko NN,Shapiro R,Maschan AA,Zokoev AK,Schekaturov SV,Vyunkova JN,Dymova OV

更新日期：2017-08-01 00:00:00

abstract：:ABO-ILT have re-emerged as an alternate option for select patients awaiting transplant. However, treatment protocols for children undergoing deceased donor ABO-ILT are not standardized. We implemented a novel IS protocol for children undergoing deceased donor ABO-ILT based on pretransplant IH titers. Children with hig...

journal_title：Pediatric transplantation

authors： Mysore KR,Himes RW,Rana A,Teruya J,Desai MS,Srivaths PR,Zaruca K,Calvert A,Guffey D,Minard CG,Morita E,Hensch L,Losos M,Kostousov V,Hui SR,Orange JS,Goss JA,Nicholas SK

更新日期：2018-11-01 00:00:00

abstract：:Potential age-dependent changes of sirolimus metabolite patterns in pediatric renal transplant recipients remain elusive. Thirteen pediatric solid organ transplant recipients (10 kidney, one combined liver-kidney, two liver, mean age 8.0 +/- 5.0 yr) underwent a sirolimus pharmacokinetic profile in steady-state with 10...

journal_title：Pediatric transplantation

authors： Filler G,Bendrick-Peart J,Strom T,Zhang YL,Johnson G,Christians U

更新日期：2009-02-01 00:00:00

abstract：:Severe portopulmonary hypertension (POPH) is a contraindication for liver transplantation (LT) because of the high risk of postoperative heart failure. The early detection of POPH is important for patients with biliary atresia (BA). Brain natriuretic peptide (BNP) is known to be correlated with liver fibrosis in patie...

journal_title：Pediatric transplantation

authors： Yoshimaru K,Matsuura T,Takahashi Y,Yanagi Y,Nagata H,Ohga S,Taguchi T

更新日期：2018-08-01 00:00:00

abstract：:Laparoscopic donor nephrectomy (LDN) is rapidly becoming the preferred technique for the procurement of living donor kidneys. An association of this technique with delayed graft function and higher risk for rejection has been reported in pediatric recipients. We reviewed our experience of 17 pediatric patients who rec...

journal_title：Pediatric transplantation

authors： Baqi N,Stock J,Lombardo SA,Geffner S,Roberti I

更新日期：2006-05-01 00:00:00

abstract：:Vaccination of pediatric liver transplant candidates and recipients represents an opportunity to decrease infectious complications following transplant. Although vaccine recommendations exist, studies have shown that many transplant candidates and recipients are under-immunized. The goals of this study were to assess ...

journal_title：Pediatric transplantation

authors： Feldman AG,Kempe A,Beaty BL,Sundaram SS,Studies of Pediatric Liver Transplantation (SPLIT) Research Group.

更新日期：2016-12-01 00:00:00

abstract：:Cystic fibrosis (CF) is associated with varying degrees of pleural inflammatory reaction that occurs as a result of chronic pulmonary infections and intervention to pleural space. The amount of pleural reaction is associated with the difficulty involved when performing the pneumonectomy at the time of lung replacement...

journal_title：Pediatric transplantation

authors： Dosanjh A,Jones L,Yuh D,Robbins RC

更新日期：1998-11-01 00:00:00

abstract：:There is a limited supply of organs for all those who need them for survival. Thus, careful decisions must be made about who is listed for transplant. Studies show that manifesting genetic disease can impact listing eligibility. What has not yet been studied is the impact genetic risks for future disease have on a pat...

journal_title：Pediatric transplantation

authors： Graf M,Char D,Hanson-Kahn A,Magnus D

更新日期：2019-06-01 00:00:00

abstract：:Epstein-Barr virus (EBV)-associated post-transplant lymphoproliferative disease (PTLD) is a serious complication of organ and bone marrow transplantation. The importance of EBV matching between recipient and donor remains unclear. Between October 1987 and December 1997, 64 pediatric cardio-pulmonary transplants were p...

journal_title：Pediatric transplantation

authors： Harwood JS,Gould FK,McMaster A,Hamilton JR,Corris PA,Hasan A,Gennery AR,Dark JH

更新日期：1999-05-01 00:00:00