解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
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神经系统科学
护理
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产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
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放射学,核医学和医学成像
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热带医学
泌尿学和肾脏学
病毒学
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心理学,临床
abstract::These studies were undertaken to assess the effects of chronic administration of cerulein plus secretin, every 8 h for 10 days on fluid, protein, and somatostatin-like immunoreactivity (SLI) outputs in rat pancreatic juice. Pancreatic secretion was studied with conscious, cannulated rats, during infusion of precollect...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198808000-00002
更新日期:1988-01-01 00:00:00
abstract::A 62-year-old Chinese woman suffering from pancreatic carcinoma coexisting with chronic calcifying pancreatitis is reported. Ultrasonography and computed tomography disclosed multiple intraductal calcifications in the pancreatic head and body and a tumor at the tail. Laparotomy revealed cancerous peritonitis in additi...
journal_title:Pancreas
pub_type: 杂志文章,评审
doi:10.1097/00006676-198802000-00020
更新日期:1988-01-01 00:00:00
abstract::A new model is proposed for pancreatic enzyme secretion in response to food protein intake in rats. We have found a novel peptide in rat bile-pancreatic juice, which exhibits a trypsin-sensitive, cholecystokinin (CCK)-releasing activity. The amino acid sequence of the peptide purified from rat bile-pancreatic juice is...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198812000-00013
更新日期:1988-01-01 00:00:00
abstract::To determine the role of endogenous pancreatic polypeptide (PP) as a physiological inhibitor of pancreatic secretion, normal rabbit serum (control) or rabbit PP-antiserum was administered intravenously to dogs with chronic esophageal, gastric, and pancreatic fistulas. In all dogs tested, sham-feeding and ordinary feed...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198709000-00008
更新日期:1987-01-01 00:00:00
abstract::Scanning electron microscopy (SEM) and energy dispersive x-ray fluorescence (EDXRF) have been used in this study to investigate the morphology, nature, and arrangement of major, minor, and trace elements in human pancreatic calculi (PC) obtained from patients with alcoholic and tropical pancreatitis. The present study...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198703000-00005
更新日期:1987-01-01 00:00:00
abstract::Dogs with chronic pancreatic fistulae were given 0.5 ml of nonimmune rabbit serum or antibody S5, an antibody raised against the C-terminal pancreatic polypeptide (PP) hexapeptide. A 3-h infusion of secretin (125 ng/kg/h) and CCK8 (50 ng/kg/h) was started 30 min after injecting serum. Exogenous BPP (400 pmol/kg/h) was...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198705000-00011
更新日期:1987-01-01 00:00:00
abstract::Peptide YY (PYY) is a recently isolated gut peptide that is found primarily in the mucosal endocrine cells of the terminal ileum, colon, and rectum of several mammalian species, including humans. The purpose of this study was to characterize the effect of PYY on pancreatic exocrine secretion in six conscious dogs prep...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198707000-00013
更新日期:1987-01-01 00:00:00
abstract::The influence of pancreatic secretions on growth and brush-border enzyme activity, throughout the entire small intestine, was examined in the rat. Pancreatic secretions were excluded from the gut lumen by stapling the pancreatic ducts, without interruption of bile flow. The entire small intestine was studied as four s...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198705000-00008
更新日期:1987-01-01 00:00:00
abstract::The present investigation provides follow-up data (up to 36 months) of exocrine and endocrine pancreatic function, inflammatory activity, pain, and body weight in 23 chronic pancreatitis patients submitted to Whipple's procedure plus intraoperative Ethibloc occlusion of the remaining pancreatic duct system between Jan...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198711000-00016
更新日期:1987-01-01 00:00:00
abstract::Atrial natriuretic factor (ANF) binding sites in adult rat exocrine pancreas were studied by autoradiography using slide-mounted frozen tissue sections with mono-iodinated ANF (101-126) as the tracer. Radiolabel was displaced by unlabeled atrial peptide (IC50 = 2 X 10(-11) M). High specific labeling was found in pancr...
journal_title:Pancreas
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::To assess the role of stapling devices and routine gastroenterostomy in palliative bypass surgery, the hospital records of 150 consecutive patients with unresectable, histologically proven pancreatic adenocarcinoma requiring palliative bypass procedure were reviewed. During recent years staplers have gained increasing...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198703000-00004
更新日期:1987-01-01 00:00:00
abstract::Pancreatic duct fragments were isolated from rat and hamster pancreas and were cultured in an agarose matrix for up to 8 weeks (rat) or 20 weeks (hamster). The fragments consisted predominantly of duct epithelium, lesser numbers of stromal and atrophied acinar cells, and small numbers of islet cells. Hamster ducts ave...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198707000-00010
更新日期:1987-01-01 00:00:00
abstract::We collected pure pancreatic juice during an entire day and examined pancreatic secretory changes induced by ordinary meals in a male patient having an external drainage of the main pancreatic duct. The ingestion of breakfast, lunch, and dinner each caused a marked increase in pancreatic secretion above basal levels. ...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198709000-00020
更新日期:1987-01-01 00:00:00
abstract::We have studied the degree of pancreatic secretory alterations assessed by secretin-cerulein test (S-C) in relation to various morphological changes detected by real-time ultrasonography (US) in 42 patients affected by chronic pancreatitis. Exocrine insufficiency was found in 41 patients (97.6%), while morphological a...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198703000-00016
更新日期:1987-01-01 00:00:00
abstract::The effect of surgical celiac and superior mesenteric ganglionectomy (GGX) on intrinsic pancreatic innervation was studied in male Wistar rats. Neurons were stained in the pancreas of control and ganglionectomized rats with histochemical methods evidencing the acetylcholinesterase (AChE) activity and the induced fluor...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198709000-00013
更新日期:1987-01-01 00:00:00
abstract::Utilizing scanning electron microscopy and isolated, vascularly perfused rat pancreas, we studied the angioarchitecture and the effect of the insulinotropic hormone, gastric inhibitory polypeptide (GIP), on cholecystokinin (CCK)-stimulated exocrine secretion. We tried to correlate the microcirculation with the physiol...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198701000-00016
更新日期:1987-01-01 00:00:00
abstract::Amyloid was isolated from islets of amyloidotic pancreata of monkey and human beings by solubilization of non-amyloid materials from the pancreas and digestion of contaminating collagen and elastin. The resulting pellet was estimated to be greater than 90% pure islet amyloid. Antibodies specific for monkey islet amylo...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198607000-00001
更新日期:1986-01-01 00:00:00
abstract::We simultaneously measured hepatic insulin removal invasively and estimated hepatic clearance and extraction of insulin pharmacokinetically from cardiac output and peripheral plasma concentrations (relatively) noninvasively. The invasive methods involved continuous electromagnetic measurements of portal venous and hep...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198611000-00013
更新日期:1986-01-01 00:00:00
abstract::In the present study, antibodies directed against clathrin light (33 kDa-36 kDa) and heavy (180 kDa) chains were used to confirm, by immunocytochemistry, that coated vesicles increase in number in the exocrine cells of pancreatic lobules incubated under anoxic (N2) conditions. The same antibodies were used to check wh...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198603000-00002
更新日期:1986-01-01 00:00:00
abstract::Conscious rats were infused with optimal doses of secretin (16 clinical units [CU]/kg/h), cerulein (0.25 microgram/kg/h), and both for varying periods of time over 24 h. The presence of zymogen granules in acinar cells and the tissue content of enzymes showed progressive decreases over 3 and 12 h for cerulein and secr...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198611000-00010
更新日期:1986-01-01 00:00:00
abstract::The effects of coffee on exocrine pancreatic secretion are unknown but may be important, because a link between chronic stimulation of pancreatic secretion and experimental chemical carcinogenesis and an association between coffee drinking and human pancreatic adenocarcinoma have been reported. We measured exocrine pa...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198601000-00011
更新日期:1986-01-01 00:00:00
abstract::The clinical, diagnostic, and therapeutic aspects of 27 patients with pancreatopleural fistula (PPF) reported in the literature, and two additional patients managed by the authors, form the basis of this report. The diagnosis of PPF is based on the triad of massive pleural effusions, elevated pleural fluid amylase, an...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198605000-00013
更新日期:1986-01-01 00:00:00
abstract::In 134 consecutive patients with acute abdominal pain, we evaluated the clinical role of a new rapid test for serum lipase based on latex agglutination. The results were compared with those obtained with a widely used lipase immunoassay as well as with serum amylase and pancreatic isoamylase measurements. Fifty-five h...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198607000-00005
更新日期:1986-01-01 00:00:00
abstract::Pancreatic insufficiency was induced in rats by a single injection of 50 microliter oleic acid into the pancreatic duct over a period of 3 min. Exocrine tissue was destroyed within 3-6 days, and after 6 weeks the remaining pancreas equaled 2.7% of the original organ. The rats showed retardation of body weight in spite...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198601000-00007
更新日期:1986-01-01 00:00:00
abstract::To examine previous work carried out at a single center, i.e., France, on the pathologic features of chronic pancreatitis and to examine geographic differences, 359 cases of chronic pancreatitis from five centers were studied pathologically and the results analyzed according to appropriate statistical methods. It was ...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198611000-00001
更新日期:1986-01-01 00:00:00
abstract::The transport specificity of L-glutamine influx in the perfused rat exocrine pancreas has been investigated using a dual isotope tracer dilution technique. During a single circulation through the isolated pancreas, an epithelial uptake of 71 +/- 1% (n = 10) was measured for L-(3H)glutamine relative to the extracellula...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198605000-00007
更新日期:1986-01-01 00:00:00