abstract：:Introduction. In May-June 2018, an outbreak of campylobacteriosis involved students and school staff from kindergartens and primary schools in Pescara, southern Italy.Aim. We present details of the epidemiological and microbiological investigation, and the findings of the analytical study, as well as the implemented c...

journal_title：Journal of medical microbiology

authors： Sorgentone S,Busani L,Calistri P,Robuffo G,Bellino S,Acciari V,Ferri M,Graziani C,Antoci S,Lodi F,Alfonsi V,Cammà C,Fazii P,Andrianou X,Cito F,Lombardi G,Centorotola G,D'Amario M,D'Alterio N,Savini V,De Massis F,

更新日期：2021-01-21 00:00:00

abstract：:Introduction.Mycoplasma genitalium is a sexually transmitted pathogen with increasing resistance to first- and second-line antimicrobials. The 'near-patient test' ResistancePlus MG FleXible (SpeeDx) detects M. genitalium plus four macrolide resistance mutations (MRMs), facilitating same-day patient follow up.Hypothesi...

journal_title：Journal of medical microbiology

authors： Murray GL,Doyle M,Bodiyabadu K,Vodstrcil LA,Garland SM,Danielewski J,Machalek DA,McGuinness C,Plummer EL,De Petra V,Williamson DA,Bradshaw CS

更新日期：2021-01-01 00:00:00

abstract：:Introduction. Infections with the respiratory pathogen Mycoplasma pneumoniae are often chronic, recurrent and resistant, persisting after antibiotic treatment. M. pneumoniae grown on glass forms protective biofilms, consistent with a role for biofilms in persistence. These biofilms consist of towers of bacteria inters...

journal_title：Journal of medical microbiology

authors： Feng M,Burgess AC,Cuellar RR,Schwab NR,Balish MF

更新日期：2021-01-01 00:00:00

abstract：:Introduction.Serratia marcescens is a bacterial pathogen that causes ventilator-associated pneumonia and ocular infections. The FlhD and FlhC proteins complex to form a heteromeric transcription factor whose regulon, in S. marcescens, regulates genes for the production of flagellum, phospholipase A and the cytolysin S...

journal_title：Journal of medical microbiology

authors： Stella NA,Brothers KM,Shanks RMQ

更新日期：2020-12-10 00:00:00

abstract：:Introduction. Rapid identification of the causative agent of sepsis is crucial for patient outcomes.Aim. The Sepsityper sample preparation method enables direct microbial identification of positive blood culture samples via matrix-assisted laser desorption ionization/time-of-flight mass spectrometry (MALDI-TOF MS).Hyp...

journal_title：Journal of medical microbiology

authors： Cordovana M,Zignoli A,Ambretti S

更新日期：2020-12-01 00:00:00

abstract：:Erysipelothrix rhusiopathiae is a zoonotic pathogen that causes erysipelas in a variety of animals. In humans, in contrast to the cutaneous form called erysipeloid, which is an occupational disease and common in individuals who handle raw meat and fish, invasive systemic infections are unusual. E. rhusiopathiae expres...

journal_title：Journal of medical microbiology

authors： Taguchi Y,Shiraiwa K,Ogawa Y,Oi T,Nakamura S,Okumura J,Shimoji Y

更新日期：2020-10-01 00:00:00

abstract：:Introduction. Melioidosis, caused by Burkholderia pseudomallei, in endemic areas, poses a challenge for treating the diseased populations without accurate diagnosis, and the disease-specific biomarkers linked with the infection have yet to be reported. Due to the invasive nature of the causative agent, Burkholderia ps...

journal_title：Journal of medical microbiology

authors： Saikh KU,Ranji CM,Ulrich RG,Corea E,De Silva AD,Natesan M

更新日期：2020-10-01 00:00:00

abstract：:Clinical specimens unfit for laboratory processing represent missed opportunities for diagnosing tuberculosis. Poor-quality cough specimens (n=61) from presumptive tuberculosis cases were cultured and GeneXpert MTB/RIF (Xpert) successfully performed on samples transferred by flocked swab into PrimeStore molecular tran...

journal_title：Journal of medical microbiology

authors： Mboneni TA,Eales OO,Mosina NL,Fourie PB

更新日期：2020-09-01 00:00:00

abstract：:Introduction. PCV2 is a DNA virus that exists widely in pigs and has caused great economic losses to the pig industry worldwide. In the existing commercial PCV2 enzyme-linked immunosorbent assay (ELISA) kits both natural infection with PCV2 and vaccine immunization produce results that are positive for PCV2 Cap antibo...

journal_title：Journal of medical microbiology

authors： Chen Q,Rong J,Li G,Xu B,Wang X,Hu J,Rong M,Li H

更新日期：2020-09-01 00:00:00

abstract：:Purpose. In this study, we differentiated between tuberculosis (TB) and infections caused by nontuberculous mycobacteria (NTM) or Nocardia in a tertiary general hospital in China. Differences in clinical manifestations and factors between respiratory infections associated with these organisms were also investigated.Me...

journal_title：Journal of medical microbiology

authors： Dong G,Chu P,Guo J,Xie Y,Lu J

更新日期：2020-09-01 00:00:00

abstract：:Introduction. Rhein (4, 5-dihydroxyanthraquinone-2-carboxylic acid) has various properties, including anti-inflammatory, antioxidant and anticancer activities. However, the mechanism underlying the role of rhein in antimicrobial activity remains largely unknown.Aim. This study aims to identify potential natural compou...

journal_title：Journal of medical microbiology

authors： Nguyen AT,Kim KY

更新日期：2020-05-01 00:00:00

abstract：:Introduction. Neonatal infection with Cronobacter sakazakii can cause severe intestinal damage and necrotizing enterocolitis (NEC). The inflammasome and Toll-like receptors mediate intestinal damage caused by other intestinal pathogens causing NEC, but the exact mechanism is unclear.Aim. We evaluated the molecular mec...

journal_title：Journal of medical microbiology

authors： Chen Z,Zhang Y,Lin R,Meng X,Zhao W,Shen W,Fan H

更新日期：2020-05-01 00:00:00

abstract：:Introduction. Quantification of bacterial load in tissue homogenates in in vivo pharmacodynamic studies is cumbersome and time-consuming.Aim. We therefore developed a new method for quantifying bacterial load in tissue homogenates of animals treated with a β-lactam and β-lactamase inhibitor using growth curves.Methods...

journal_title：Journal of medical microbiology

authors： Georgiou PC,Mouton JW,Pournaras S,Meletiadis J

更新日期：2020-05-01 00:00:00

abstract：:Purpose. Antimicrobial susceptibility is slow to determine, taking several days to fully impact treatment. This proof-of-concept study assessed the feasibility of using machine-learning techniques for analysis of data produced by the flow cytometer-assisted antimicrobial susceptibility test (FAST) method we developed....

journal_title：Journal of medical microbiology

authors： Inglis TJJ,Paton TF,Kopczyk MK,Mulroney KT,Carson CF

更新日期：2020-05-01 00:00:00

abstract：:Introduction. The emergence of novel strains of Vibrio cholerae O1 El Tor biotype has gained attention due to causing several epidemics around the world. Variant strains have evolved as a result of the acquisition of genes that confer extended virulence and pathogenicity.Aim. This study aimed to determine the presence...

journal_title：Journal of medical microbiology

authors： Mohanraj RS,Samanta P,Mukhopadhyay AK,Mandal J

更新日期：2020-03-01 00:00:00

abstract：:Introduction. Ocular microsporidiosis is a significant emerging infectious disease reported in immunocompromised patients and immunocompetent persons throughout the world.Aim. To identify the pathogens responsible for human keratitis, via corneal scrapings.Methodology. Thirty-three hospitalized patients with epithelia...

journal_title：Journal of medical microbiology

authors： Sanpool O,Thanathanee O,Laummuanwai P,Maleewong W,Intapan PM

更新日期：2020-03-01 00:00:00

abstract：:Introduction. Current testing practices for yersiniosis mean that its true incidence and epidemiology are not well understood. In mid-2016, the introduction of testing via a multiplex gastrointestinal PCR panel at Portsmouth hospital laboratory in Hampshire, UK, resulted in a marked increase in the number of Yersinia ...

journal_title：Journal of medical microbiology

authors： Clarke M,Dabke G,Strakova L,Jenkins C,Saavedra-Campos M,McManus O,Paranthaman K

更新日期：2020-03-01 00:00:00

abstract：:The advent of next-generation sequencing technology has revolutionized the field of prokaryotic genetics and genomics by allowing interrogation of entire genomes, transcriptomes and global transcription factor binding profiles. As more studies employing these techniques have been performed, the state of the art regard...

journal_title：Journal of medical microbiology

authors： Valli RXE,Lyng M,Kirkpatrick CL

更新日期：2020-02-01 00:00:00

abstract：:Introduction. Differences between the genomic and virulence profile of Bordetella pertussis circulating strains and vaccine strains are considered as one of the important reasons for the resurgence of whooping cough (pertussis) in the world. Genetically inactivated B. pertussis is one of the new strategies to generate...

journal_title：Journal of medical microbiology

authors： Nikbin VS,Keramati M,Noofeli M,Tayebzadeh F,Kahali B,Shahcheraghi F

更新日期：2020-01-01 00:00:00

abstract：:Pseudomonas aeruginosa is an opportunistic pathogen that produces several virulence factors such as lectin A, pyocyanin, elastase and rhamnolipids. These compounds are controlled transcriptionally by three quorum-sensing circuits, two based on the synthesis and detection of N-acyl-homoserine-lactone termed the Las and...

journal_title：Journal of medical microbiology

authors： García-Reyes S,Soberón-Chávez G,Cocotl-Yanez M

更新日期：2020-01-01 00:00:00

abstract：:Introduction. The worldwide emergence of carbapenem resistance in Gram-negative bacteria makes the development of simple tests mandatory to identify antimicrobial resistance mechanisms. Enzymatic and membrane barriers are the prominent resistance mechanisms described in these bacteria. Several tests are currently used...

journal_title：Journal of medical microbiology

authors： Pinet E,Franceschi C,Collin V,Davin-Regli A,Zambardi G,Pagès JM

更新日期：2020-01-01 00:00:00

abstract：:Enteroaggregative Escherichia coli (EAEC), a highly heterogeneous pathotype of E. coli classified as typical and atypical, are an emerging cause of acute and persistent diarrhea. We aimed to investigate whether population living in rural geographic areas, impacts in the heterogeneity, dissemination and antimicrobial s...

journal_title：Journal of medical microbiology

authors： Guerrieri CG,Monfardini MV,Silva EA,Bueno de Freitas L,Schuenck RP,Spano LC

更新日期：2020-01-01 00:00:00

abstract：:Purpose. Acute bacterial meningitis continues to be a potentially life threatening condition. Hospital-acquired meningitis is rapidly increasing and adding an immense burden to the health system due to the emergence of multidrug resistance isolates. The purpose of this study is to find the antibiotic susceptibility pa...

journal_title：Journal of medical microbiology

authors： Raza MS,Das BK,Goyal V,Lodha R,Chaudhry R,Sood S,Gautam H,Sreenivas V,Nair D,Mohapatra S,Kapil A

更新日期：2019-11-01 00:00:00

abstract：:Aim. The aim of this work was to characterize the response of Candida albicans to atorvastatin, and to assess its in vivo antifungal capability.Methodology. The effect of atorvastatin on the growth and viability of C. albicans was assessed. The ability of the statin to alter cell permeability was quantified by measuri...

journal_title：Journal of medical microbiology

authors： Ajdidi A,Sheehan G,Abu Elteen K,Kavanagh K

更新日期：2019-10-01 00:00:00

abstract：:Introduction. Pseudomonas aeruginosa is an important Gram-negative pathogen that is intrinsically multidrug-resistant (MDR) and frequently associated with healthcare-associated outbreaks. With increasing resistance to antibiotics and with very few novel drugs under development, clinicians often use combinations to tre...

journal_title：Journal of medical microbiology

authors： Betts JW,Hornsey M,Higgins PG,Lucassen K,Wille J,Salguero FJ,Seifert H,La Ragione RM

更新日期：2019-10-01 00:00:00

abstract：:Introduction.Candida auris is a pathogenic yeast that mainly affects immunosuppressed patients and those with implanted medical devices. This pathogen also displays elevated resistance to common antifungals and high survival and spreading capacities. Since no antifungal breakpoints have yet been defined for this patho...

journal_title：Journal of medical microbiology

authors： Romera D,Aguilera-Correa JJ,Gadea I,Viñuela-Sandoval L,García-Rodríguez J,Esteban J

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:In an increasing number of cases the last therapeutic option for treatment of carbapenem-resistant Enterobacteriaceae is colistin. As the detection of colistin resistance is problematic and time-consuming, it is desirable to find a rapid and reliable test. The rapid polymyxin NP test developed by Nordmann et al...

journal_title：Journal of medical microbiology

authors： Belda-Orlowski A,Pfennigwerth N,Gatermann SG,Korte-Berwanger M

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:This study aimed to investigate the effect of smoking on the buccal microbiome and to analyse the descriptive ability of each of the seven hypervariable regions in their 16S rRNA genes. METHODOLOGY:Microbiome compositions of 40 buccal swab samples collected from smokers (n =20) and non-smokers (n =20) were det...

journal_title：Journal of medical microbiology

authors： Karabudak S,Ari O,Durmaz B,Dal T,Basyigit T,Kalcioglu MT,Durmaz R

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:We examined evidence for transmission of Pandorea apista among cystic fibrosis (CF) patients attending paediatric and adult services in one city who had previously been found to harbour related isolates by pulsed-field gel electrophoresis (PFGE). METHODOLOGY:The whole-genome sequences of 18 isolates from this ...

journal_title：Journal of medical microbiology

authors： Kenna DTD,Coward A,Perry C,Pike R,Schaefer U,Turton J,Green H,Jones AM,Bright-Thomas RJ,Burns P,Narayan O,Wilkinson S,Turton JF

更新日期：2019-07-01 00:00:00

abstract：PURPOSE:Extensively drug-resistant (XDR) strains of Acinetobacter baumannii are being reported worldwide, and they are associated with high morbidity and mortality rates. These strains are considered to be the highest priority for the development of new antibacterial agents. Therefore, we aimed to develop an effective ...

journal_title：Journal of medical microbiology

authors： Wintachai P,Naknaen A,Pomwised R,Voravuthikunchai SP,Smith DR

更新日期：2019-07-01 00:00:00

abstract：PURPOSE:This study investigated the efficacy of the essential mineral, selenium (sodium selenite), in reducing the toxin production, spore outgrowth and antibiotic resistance of Clostridium difficile in vitro. METHODOLOGY:Two hypervirulent C. difficile isolates were cultured in brain heart infusion broth with and with...

journal_title：Journal of medical microbiology

authors： Pellissery AJ,Vinayamohan PG,Yin HB,Mooyottu S,Venkitanarayanan K

更新日期：2019-07-01 00:00:00

abstract：INTRODUCTION:The last few years have seen the emergence of multi-drug resistant (MDR) Gram-negative infections, which are associated with high morbidity and mortality. The indiscriminate use of colistin has led to the development of resistance, which can be diagnosed effectively by broth microdilution. Studies from Ind...

journal_title：Journal of medical microbiology

authors： Kaza P,Mahindroo J,Veeraraghavan B,Mavuduru RS,Mohan B,Taneja N

更新日期：2019-06-01 00:00:00

abstract：:Dermatophytes are a highly specialized group of keratinophilic and keratinolytic filamentous fungi causing a ringworm disease called dermatophytosis or superficial mycoses. Although dermatophyte infections do not threaten the host's life, they lower its quality in humans by causing discomfort related to cosmetic probl...

journal_title：Journal of medical microbiology

authors： Gnat S,Nowakiewicz A,Łagowski D,Zięba P

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:Comparative genomic analysis of strains may help us to better understand the wide diversity of their genetic profiles. The aim of this study was to analyse the genomic features of the resistome and virulome of Brazilian first methicillin-resistant Staphylococcus aureus (MRSA) isolates and their relationship to ...

journal_title：Journal of medical microbiology

authors： de Carvalho SP,de Almeida JB,de Freitas LM,Guimarães AMS,do Nascimento NC,Dos Santos AP,Campos GB,Messick JB,Timenetsky J,Marques LM

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:The present study evaluated the possible synergistic antimycobacterial interactions of Juniperus communis and Helichrysum italicum essential oils (EO). METHODS:Antimycobacterial potential was tested against Mycobacterium avium and Mycobacterium intracellulare using broth and water dilution method and checker...

journal_title：Journal of medical microbiology

authors： Peruč D,Tićac B,Abram M,Broznić D,Štifter S,Staver MM,Gobin I

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:Antimicrobial resistance (AMR) is of increasing global concern, threatening to undermine recent progress in reducing child and neonatal mortality. Repurposing older antimicrobials is a prominent strategy to combat multidrug-resistant sepsis. A potential agent is fosfomycin, however, there is scarce data regardi...

journal_title：Journal of medical microbiology

authors： Williams PCM,Waichungo J,Gordon NC,Sharland M,Murunga S,Kamau A,Berkley JA

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:Penicillium is the most common mould isolated in housing. Penicillium chrysogenum is the only species tested by prick test or serology for allergic patients. The American Institute of Medicine has accepted Penicillium as an aetiological agent of rhinitis in children and adults and as an asthma agent in children...

journal_title：Journal of medical microbiology

authors： Reboux G,Rocchi S,Vacheyrou M,Millon L

更新日期：2019-05-01 00:00:00

abstract：:The move towards pathology networks and hub-and-spoke models of medical laboratory service provision has significantly changed the flow of samples, and the impact of results on patients, over recent years. At the same time advances in technology, including rapid, simple to use molecular platforms, are changing the way...

journal_title：Journal of medical microbiology

authors： Rabinowicz S,O'Hare M,Moore LSP,Mughal N

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To analyse the role of virulence factors (VFs) and host in Klebsiella pneumoniae upper urinary tract infections (UTIs) in renal transplant (RTx) recipients. METHODOLOGY:Clinical and demographic data were registered prospectively. Phylogenetic background of K. pneumoniae isolates was analysed by PCR melting pro...

journal_title：Journal of medical microbiology

authors： Gołębiewska JE,Krawczyk B,Wysocka M,Ewiak A,Komarnicka J,Bronk M,Rutkowski B,Dębska-Ślizień A

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:Extracellular protein toxins contribute to the pathogenesis of Staphylococcus aureus infections. The present study compared the effects of iclaprim and trimethoprim - two folic acid synthesis inhibitors - with nafcillin and vancomycin on production of Panton-Valentine leukocidin (PVL), alpha haemolysin (AH) and...

journal_title：Journal of medical microbiology

authors： Bryant AE,Gomi S,Katahira E,Huang DB,Stevens DL

更新日期：2019-03-01 00:00:00