解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::1. Estrogens have been shown to decrease the effect of apomorphine in a variety of animal behavioral models reflecting the sensitivity of striatal and mesolimbic dopamine receptors. 2. These include circling, and locomotor activity, in rats and suppression of midbrain tremor as well as lingual dyskinesia in monkeys. 3...
journal_title:Progress in neuro-psychopharmacology & biological psychiatry
pub_type: 杂志文章
doi:10.1016/s0278-5846(82)80149-8
更新日期:1982-01-01 00:00:00
abstract::1. By study of the synthesis and turnover of brain monoamines and with the use of behavioral models which indicate the functional activity of brain 5HT and dopamine, it is possible to unravel the mechanisms by which some drugs produce behavioral effects. 2. Using these techniques the acute and chronic effects of certa...
journal_title:Progress in neuro-psychopharmacology
pub_type: 杂志文章,评审
doi:10.1016/0364-7722(79)90065-1
更新日期:1979-01-01 00:00:00
abstract::1. AHR-6646 blocked d-amphetamine lethality in mice under aggregated conditions when the pretreatment interval was between one hour and seven days. 2. Conditioned avoidance responding in mice and cats was suppressed by AHR-6646 in doses that did not impair escape behavior. The duration of this effect was markedly prol...
journal_title:Progress in neuro-psychopharmacology
pub_type: 杂志文章
doi:10.1016/0364-7722(79)90005-5
更新日期:1979-01-01 00:00:00
abstract::1. Communication among scientists of similar professional interest is an often neglected but critical factor in medical research and practice. 2. Dissemination of information is vital for keeping abreast of one's field, for planning studies and treatment regimens, and for avoiding unnecessary research. 3. Today's comm...
journal_title:Progress in neuro-psychopharmacology
pub_type: 杂志文章
doi:10.1016/0364-7722(79)90077-8
更新日期:1979-01-01 00:00:00
abstract::Muscimol, ibotenic acid, isoguvacine, 4,5,6,7-tetrahydroisoxazolo [5,4-c]pyridin-3-ol (THIP) and gamma-aminobutyric acid (GABA) injected intravenously exerted the following dose-dependent effects on the lumbosacral spinal cord of spinal cats: 1. The excitability of primary afferents and the amplitude of dorsal root re...
journal_title:Progress in neuro-psychopharmacology
pub_type: 杂志文章
doi:10.1016/0364-7722(79)90045-6
更新日期:1979-01-01 00:00:00
abstract::1. The first part of the paper is devoted to a critical review on the possible relationships between depression and monoamine oxidase. 2. This study describes the results of an investigation of MAO-activity in depression, using new approaches and methodology. This methodology was developed because the literature data ...
journal_title:Progress in neuro-psychopharmacology
pub_type: 杂志文章
doi:10.1016/0364-7722(79)90000-6
更新日期:1979-01-01 00:00:00
abstract::1. The effects of apomorphine and sodium Di-n-propylacetate (DPA, sodium valproate) on pain-induced aggressive behavior were investigated in three inbred strains of mice: BALB/c, C57B1/6 and DBA/2, which exhibited spontaneously low levels of aggression. 2. Apomorphine elicited aggressive behavior in the three strains,...
journal_title:Progress in neuro-psychopharmacology
pub_type: 杂志文章
doi:10.1016/0364-7722(79)90003-1
更新日期:1979-01-01 00:00:00
abstract::1. The range of tricyclic antidepressant plasma levels (or doses) needed for therapeutic response remains largely unresolved, since quantal plasma concentration (or dose)--response relationships have not been clearly defined for either therapeutic or nontherapeutic effects. 2. The fact that certain patients apparently...
journal_title:Progress in neuro-psychopharmacology
pub_type: 杂志文章,评审
doi:10.1016/0364-7722(79)90085-7
更新日期:1979-01-01 00:00:00
abstract::1. Some recent findings on fetal alcohol effects are presented under the headings of introduction, classification--clinical signs and symptoms, epidemiology, etiology--possible pathogenesis, diagnosis, prognosis, management, discussion and conclusions. 2. The present level of knowledge suggests that the toxic effects ...
journal_title:Progress in neuro-psychopharmacology
pub_type: 杂志文章,评审
doi:10.1016/0364-7722(79)90001-8
更新日期:1979-01-01 00:00:00