解剖学和形态学
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牙科,口腔外科和医学
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老人病学和老年医学
卫生保健科学和服务
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abstract::Heterogeneous practices exist across transplant centres regarding assessment prior to allogeneic haematopoietic cell transplantation (allo-HCT) for myelofibrosis, post-transplant monitoring and management of relapse. The 'Practice Harmonisation and Guidelines' and Myeloproliferative Neoplasms subcommittees of the Chro...
journal_title:Current research in translational medicine
pub_type: 杂志文章
doi:10.1016/j.retram.2020.08.003
更新日期:2020-10-15 00:00:00
abstract::Graft-versus-host disease (GvHD) is a common complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT) with high morbidity and mortality rates. The purpose of this study was to demonstrate the efficacy of Manual Lymph Drainage (MLD) and a home-based exercise programme on range of motion (ROM) and ...
journal_title:Current research in translational medicine
pub_type: 杂志文章
doi:10.1016/j.retram.2019.11.001
更新日期:2020-01-01 00:00:00
abstract:PURPOSE OF THE STUDY:Two chimeric antigen receptor (CAR) T-cell therapies - Tisagenlecleucel (Kymriah™) and Axicabtagene ciloleucel (Yescarta™) - have been approved for commercial use. In order to inform forthcoming EBMT guidelines on the management of adults and children undergoing autologous CAR T-cell therapy, we un...
journal_title:Current research in translational medicine
pub_type: 杂志文章
doi:10.1016/j.retram.2019.05.002
更新日期:2019-08-01 00:00:00
abstract::Diabetic retinopathy (DR) and retinopathy of prematurity (ROP) present two examples of proliferative retinopathy, characterized by the same stages of progression; ischemia of the retinal vessels, leads to hypoxia and to correct the problem there is the setting up of uncontrolled angiogenesis, which subsequently causes...
journal_title:Current research in translational medicine
pub_type: 杂志文章,评审
doi:10.1016/j.retram.2019.01.005
更新日期:2019-05-01 00:00:00
abstract::Studies have shown that the NRF-2 /HO-1 pathway participates in myocardial ischemic reperfusion injury (MI/R) and that Geniposide (GEN) could protect the myocardial against MI/R. This study aims to examine the protective effects of GEN on MI/R in diabetic rats and further explore the possible mechanism of action. Duri...
journal_title:Current research in translational medicine
pub_type: 杂志文章
doi:10.1016/j.retram.2019.03.002
更新日期:2019-05-01 00:00:00
abstract::Hyper IgM (HIGM) syndromes are a complex of primary immunodeficiency disorders. A 4-years-old boy with recurrent fever and chills, dyspnea, sort throat for a month was admitted to emergency department. In the current case, whole exome sequencing followed by Sanger sequencing were employed in order to screen probable f...
journal_title:Current research in translational medicine
pub_type: 杂志文章
doi:10.1016/j.retram.2018.02.001
更新日期:2019-02-01 00:00:00
abstract:PURPOSE OF THE STUDY:While acute graft-versus-host-disease (GVHD) is a T cell-mediated disease caused by alloreactive donor T cells, we and others have highlighted that patients who received higher proportion of donor CD4+ naïve and central memory T cells expressing the chemokine receptor 7 (CCR7) more often developed ...
journal_title:Current research in translational medicine
pub_type: 杂志文章
doi:10.1016/j.retram.2018.11.002
更新日期:2019-02-01 00:00:00
abstract:PURPOSE OF THE STUDY:Mesenchymal stromal cells (MSCs) are considered a promising tool for cell therapy approaches. The translation of research-based cell culture protocols into procedures that comply with Good Manufacturing Practice (GMP) is critical. The aim of this study was to design a new method for the expansion o...
journal_title:Current research in translational medicine
pub_type: 杂志文章
doi:10.1016/j.retram.2018.06.002
更新日期:2019-02-01 00:00:00
abstract::The development of genomic editing technologies expands the landscape of T cell engineering for adoptive cell therapy. Among the multiple tools that can be used, CRISPR/Cas9 has been shown to be relatively easy to use, simple to design and cost effective with highly efficient multiplex genome engineering capabilities....
journal_title:Current research in translational medicine
pub_type: 杂志文章,评审
doi:10.1016/j.retram.2018.04.003
更新日期:2018-05-01 00:00:00
abstract::Based on animal studies and serendipitous clinical cases, haematopoietic stem cell transplantation (HSCT) has been used since 1995 as a specific treatment for patients with severe treatment-resistant autoimmune disease (ADs). Despite other clinical developments for autoimmune diseases, including biological therapies, ...
journal_title:Current research in translational medicine
pub_type: 杂志文章,评审
doi:10.1016/j.retram.2016.03.003
更新日期:2016-04-01 00:00:00
abstract::Research into how the central nervous system (CNS) and the skin of mammals are physiologically connected and how this "brain-skin connection" may be therapeutically targeted in clinical medicine has witnessed a renaissance. A key element in this development has been the discovery that mammalian skin and its appendages...
journal_title:Current research in translational medicine
pub_type: 杂志文章,评审
doi:10.1016/j.retram.2016.10.003
更新日期:2016-01-01 00:00:00