Abstract:
:Various vertebrates use ultraviolet (UV) vision for such basic behaviors as mating, foraging, and predation. We have successfully interchanged the color-sensitivities of the mouse UV pigment and the human blue pigment by introducing forward and reverse mutations at five sites. This unveils for the first time the general mechanism of UV vision. Most contemporary UV pigments in vertebrates have maintained their ancestral functions by accumulating no more than one of the five specific amino acid changes. The avian lineage is an exception, where the ancestral pigment lost UV-sensitivity but some descendants regained it by one amino acid replacement at an entirely different site.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Yokoyama S,Shi Ydoi
10.1016/s0014-5793(00)02269-9keywords:
subject
Has Abstractpub_date
2000-12-08 00:00:00pages
167-72issue
2eissn
0014-5793issn
1873-3468pii
S0014-5793(00)02269-9journal_volume
486pub_type
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