Abstract:
:The possible regulation of the expression of uncoupling protein-2 (UCP2) mRNA by thyroid hormones in different tissues was examined in rats. Triiodothyronine (T3) was found to produce an organ-specific enhancement of UCP2 expression in rat tissues. The effect of T3 was markedly observed in heart, whereas a moderate effect was seen in skeletal muscle and no effect in kidney or liver. These results suggest that UCP2 is a protein that may be involved in the nuclear-mediated effect of T3 on resting metabolic rate in the rat.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Lanni A,De Felice M,Lombardi A,Moreno M,Fleury C,Ricquier D,Goglia Fdoi
10.1016/s0014-5793(97)01375-6subject
Has Abstractpub_date
1997-11-24 00:00:00pages
171-4issue
1-2eissn
0014-5793issn
1873-3468pii
S0014-5793(97)01375-6journal_volume
418pub_type
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