Superproduction of heavy minicircular mitochondrial DNA in aging wheat coleoptiles.

abstract：:Signal recognition particle (SRP) interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the endoplasmic reticulum. Membrane targeting is mediated by the 68 and the 72 kDa proteins of SRP. We have cloned and sequenced cDNA encoding the 68 kDa protein of canine...

journal_title：FEBS letters

authors： Herz J,Flint N,Stanley K,Frank R,Dobberstein B

更新日期：1990-12-10 00:00:00

abstract：:In Gram-positive bacteria the tRNA-dependent T box riboswitch regulates the expression of many amino acid biosynthetic and aminoacyl-tRNA synthetase genes through a transcription attenuation mechanism. The Specifier domain of the T box riboswitch contains the Specifier sequence that is complementary to the tRNA antico...

journal_title：FEBS letters

authors： Chang AT,Nikonowicz EP

更新日期：2013-11-01 00:00:00

abstract：:Measurement of the weight of desmosterol produced during its biosynthesis in the presence of tritiated water and triparanol has permitted a direct determination of the relative flux of carbon and tritium (the H/C ratio) into sterol in hepatocytes. The H/C ratio increased with time of incubation irrespective of the nut...

journal_title：FEBS letters

authors： Björnsson OG,Pullinger CR,Gibbons GF

更新日期：1985-08-05 00:00:00

abstract：:Small interfering (si)RNAs isolated from Brassica juncea leaves infected by Turnip mosaic virus (TuMV) were characterized by cloning and sequencing. The TuMV siRNA population was dominated by 21 and 22-nt long species originated mainly from the same siRNA hotspots, indicating operational similarity between the plant D...

journal_title：FEBS letters

authors： Ho T,Wang H,Pallett D,Dalmay T

更新日期：2007-07-10 00:00:00

abstract：:We have purified and partially sequenced two proteins from Xenopus laevis previtellogenic oocytes, belonging to messenger ribonucleoprotein particles (mRNPs). The purification procedure rests on the thermostability of these proteins, which remain soluble after heating the cell extracts at 80 degrees C. The thermostabl...

journal_title：FEBS letters

authors： Deschamps S,Viel A,Denis H,le Maire M

更新日期：1991-04-22 00:00:00

abstract：:In bovine heart mitochondria a protein of M(r) 18 kDa, phosphorylated by mtPKA, is associated to the NADH-ubiquinone oxidoreductase in the inner membrane and is present in purified preparation of this complex. The 18 kDa phosphoprotein has now been isolated and sequenced. It is identified as the 18 kDa (IP) AQDQ subun...

journal_title：FEBS letters

authors： Papa S,Sardanelli AM,Cocco T,Speranza F,Scacco SC,Technikova-Dobrova Z

更新日期：1996-02-05 00:00:00

abstract：:The ADP(Mg2+)-deactivated oligomycin-sensitive F1-F0 ATPase of coupled submitochondrial particles treated with the substoichiometric amount of oligomycin was studied to test whether ATP synthesis and hydrolysis proceed in either direction through the same intermediates. The initial rates of ATP hydrolysis, oxidative p...

journal_title：FEBS letters

authors： Syroeshkin AV,Vasilyeva EA,Vinogradov AD

更新日期：1995-06-05 00:00:00

abstract：:Tertiary structure models of Interleukin-6 were constructed using a routine prediction method based on the X-ray crystal structures of granulocyte colony-stimulating factor (GCSF) and leukemia inhibitory factor (LIF). The models were evaluated with the aid of the sequence-structure compatibility (3D-1D) method program...

journal_title：FEBS letters

authors： Sumikawa H,Fukuhara K,Suzuki E,Matsuo Y,Nishikawa K

更新日期：1997-03-10 00:00:00

abstract：:Because A2 adenosine receptor activation stimulates adenylate cyclase and cyclic AMP induces 5'-nucleotidase expression in rat mesangial cells, we examined the effect of adenosine and its analogs on 5'-nucleotidase activity in these cells. A2 adenosine receptors were characterized using [3H]5'-N-ethylcarboxamidoadenos...

journal_title：FEBS letters

authors： Stefanovic V,Vlahovic P,Savic V,Ardaillou N,Ardaillou R

更新日期：1993-09-27 00:00:00

abstract：:Phospholipase A2 has been purified from the venom of Horned viper (Cerastes cerastes) by gel permeation chromatography followed by reverse-phase HPLC. The primary structure was established by sequence analysis of the intact protein and its enzymic peptides. The structure has 120 residues, properties like other group I...

journal_title：FEBS letters

authors： Siddiqi AR,Shafqat J,Zaidi ZH,Jörnvall H

更新日期：1991-01-14 00:00:00

abstract：:We have found that the sign of phototaxis, i.e. the direction of phototactic migration either towards or away from the light source, of wild-type Chlamydomonas reinhardtii depends on its photosynthetic activity. This accounts for the frequently reported transient positive phototaxis that precedes a negative phototaxis...

journal_title：FEBS letters

authors： Takahashi T,Watanabe M

更新日期：1993-12-28 00:00:00

abstract：:A colostral proline-rich polypeptide complex (PRP) consisting of over 30 peptides shows beneficial effects in Alzheimer's disease (AD) patients when administered in the form of sublinqual tablets called Colostrinin. The aim of the present studies was to investigate whether nanopeptide fragment of PRP (NP) - one of the...

journal_title：FEBS letters

authors： Janusz M,Woszczyna M,Lisowski M,Kubis A,Macała J,Gotszalk T,Lisowski J

更新日期：2009-01-05 00:00:00

abstract：:A full-length cDNA clone encoding steroid 11 beta-hydroxylase (P-45011 beta) has been isolated from a cDNA library derived from human adrenal tumor. The insert of the clone contains an open reading frame encoding a protein of 503 amino acid residues together with a 4 bp 5'-untranslated region and a 576 bp 3'-untransla...

journal_title：FEBS letters

authors： Kawamoto T,Mitsuuchi Y,Toda K,Miyahara K,Yokoyama Y,Nakao K,Hosoda K,Yamamoto Y,Imura H,Shizuta Y

更新日期：1990-09-03 00:00:00

abstract：:The nervous and immune systems have similar functional characteristics. Both have an intricate network of synaptic connections and an exquisite communication system that enable intercellular signal transduction. Although semaphorins were originally identified as guidance cues in neural development, accumulating eviden...

journal_title：FEBS letters

authors： Okuno T,Nakatsuji Y,Kumanogoh A

更新日期：2011-12-01 00:00:00

abstract：:Chlorogenic acid (CGA; 3-o-caffeoylquinic acid), a phenylpropanoid metabolite of plants, was oxidized by H2O2 in the presence of horseradish peroxidase. The primary and secondary oxidized products both were free radicals which gave EPR multiline signals at g = 2.0044 and 2.0042 in the presence of zinc as a spin stabil...

journal_title：FEBS letters

authors： Yamasaki H,Grace SC

更新日期：1998-02-06 00:00:00

abstract：:Using model spontaneously reverting cell lines, c-jun, junB, junD and c-fos oncogene expression was investigated. c-jun, but not junB, junD or c-fos, was overexpressed in highly tumorigenic clones. The reversion of cells to the non-tumorigenic phenotype resulted in a dramatic decrease in c-jun expression. CAT assays r...

journal_title：FEBS letters

authors： Lavrovsky Y,Yefremov Y,Lavrovsky V

更新日期：1994-12-19 00:00:00

abstract：:Hormone-sensitive lipase (HSL) is responsible for the neutral cholesterol ester hydrolase activity in macrophages. Incubation of intact WEHI macrophages or mouse peritoneal macrophages leads to phosphorylation of HSL, which is increased by incubation with either dibutyryl cyclic AMP and 3-isobutyl-1-methylxanthine or ...

journal_title：FEBS letters

authors： Small CA,Rogers MP,Goodacre JA,Yeaman SJ

更新日期：1991-02-25 00:00:00

abstract：:Using rheumatoid arthritis (RA) and periodontitis mouse models, we demonstrate that RA and periodontitis share many pathological features, such as deregulated cytokine production, increased immune-cell infiltration, increased expression of Toll-like receptors (TLRs), and enhanced osteoclast activity and bone erosion. ...

journal_title：FEBS letters

authors： Hao L,Zhu G,Lu Y,Wang M,Jules J,Zhou X,Chen W

更新日期：2015-05-22 00:00:00

abstract：:The AMP-activated protein kinase (AMPK) is the central component of a protein kinase cascade that plays a major role in energy sensing. AMPK is activated pharmacologically by 5-amino-4-imidazolecarboxamide (AICA) riboside monophosphate (ZMP), which mimics the effects of AMP on the AMPK cascade. Here we show that uptak...

journal_title：FEBS letters

authors： Fryer LG,Parbu-Patel A,Carling D

更新日期：2002-11-06 00:00:00

abstract：:The alternative nitrogenase of Rhodobacter capsulatus, isolated from a nifHDK deletion mutant, has been purified to near homogeneity and identified as an 'iron only' nitrogenase. The dithionite-reduced component 1 ('FeFe protein') of this enzyme showed an EPR spectrum consisting of two components: a minor S = 1/2 sign...

journal_title：FEBS letters

authors： Müller A,Schneider K,Knüttel K,Hagen WR

更新日期：1992-05-25 00:00:00

abstract：:The somatostatin upstream enhancer (SMS-UE) is a highly complex enhancer element. The distal A-element contains overlapping Pdx1 and Pbx binding sites. However, a point mutation in the A-element that abolishes both Pdxl and Pbx binding does not impair promoter activity. In contrast, a point mutation that selectively e...

journal_title：FEBS letters

authors： Andersen FG,Jensen J,Heller RS,Petersen HV,Larsson LI,Madsen OD,Serup P

更新日期：1999-02-26 00:00:00

abstract：:Bovine globin has been incubated with mice peritoneal macrophages in order to study its hydrolysis by lysosomal enzymes, among which chiefly cathepsin D. Analysis of resulting peptides, by reversed-phase high-performance liquid chromatography (RP-HPLC), showed the release of a bioactive peptide, VV-hemorphin-7. When a...

journal_title：FEBS letters

authors： Dagouassat N,Garreau I,Sannier F,Zhao Q,Piot JM

更新日期：1996-03-11 00:00:00

abstract：:Mg2+ -dependent catechol-O-methyltransferases occur in animals as well as in bacteria, fungi and plants, often with a pronounced selectivity towards one of the substrate's hydroxyl groups. Here, we show that the bacterial MxSafC exhibits excellent regioselectivity for para as well as for meta methylation, depending on...

journal_title：FEBS letters

authors： Siegrist J,Netzer J,Mordhorst S,Karst L,Gerhardt S,Einsle O,Richter M,Andexer JN

更新日期：2017-01-01 00:00:00

abstract：:The metabolism of 20:4 (arachidonic acid) in alkenylacyl, alkylacyl and diacyl lipid classes in choline glycerophospholipids (CGP) and ethanolamine glycerophospholipids (EGP) in rabbit alveolar macrophages was examined. [3H]20:4 was very rapidly incorporated into diacyl glycerophosphocholine (GPC). After the removal o...

journal_title：FEBS letters

authors： Sugiura T,Katayama O,Fukui J,Nakagawa Y,Waku K

更新日期：1984-01-09 00:00:00

abstract：:Here we report that splice blocking morpholinos (Sb MO) against zebrafish sox31 elicit developmental arrest, likely through creating a series of dominant negative splicing variants. Embryos injected with the Sb MO develop normally before the Mid-Blastula Transition (MBT); however, they do not initiate epiboly. Microar...

journal_title：FEBS letters

authors： Hu SN,Yu H,Zhang YB,Wu ZL,Yan YC,Li YX,Li YY,Li YP

更新日期：2012-02-03 00:00:00

abstract：:A poly(A) tail functions in mRNA turnover and in facilitating translation as a ribonucleoprotein complex with poly(A) binding proteins (PABPs). However, factors that associate with the poly(A) tail other than PABPs have not been described. Using proteomics, we identified candidate proteins that interact to the 3' term...

journal_title：FEBS letters

authors： Aoki K,Adachi S,Homoto M,Kusano H,Koike K,Natsume T

更新日期：2013-07-11 00:00:00

abstract：:RB, p53 and p21(Sdi1/WAF1/Cip1) interact in the induction of G1 arrest. We established osteosarcoma cell lines in which a tetracycline-regulatable promoter controls the induction of RB, p53 and p21. By using these cell lines, we investigated whether RB, p53 or p21 regulates, in the same manner or differently, expressi...

journal_title：FEBS letters

authors： Ookawa K,Tsuchida S,Kohno T,Yokota J

更新日期：2001-06-29 00:00:00

abstract：:The major mono- and disialogangliosides of the extensively characterized established human glioma line D54MG were isolated and purified from subcutaneous solid xenografts grown in athymic (nu/nu) mice. Structural determination showed that they belonged to the lactotetraosylceramide series. The sialyllactotetraosylcera...

journal_title：FEBS letters

authors： Månsson JE,Fredman P,Bigner DD,Molin K,Rosengren B,Friedman HS,Svennerholm L

更新日期：1986-05-26 00:00:00

abstract：:The eukaryotic Ssu72 factor is involved in several RNA biogenesis processes. It has phosphatase activity on the carboxy-terminal domain (CTD) of the major subunit of RNA polymerase II. The Kluyveromyces lactis Ssu72 (KlSsu72) shows in vitro phosphatase activity for the pNPP substrate, and this activity is inhibited by...

journal_title：FEBS letters

authors： Rodríguez-Torres AM,Lamas-Maceiras M,García-Díaz R,Freire-Picos MA

更新日期：2013-08-19 00:00:00

abstract：:The article presents the results of the first regular study of Russian populations by sequencing the control region of mitochondrial DNA (mtDNA). The sequenced region is the most variable on mtDNA molecule and is commonly used for population and evolutionary studies. Russians form one of the largest ethnic groups (mor...

journal_title：FEBS letters

authors： Orekhov V,Poltoraus A,Zhivotovsky LA,Spitsyn V,Ivanov P,Yankovsky N

更新日期：1999-02-19 00:00:00