Abstract：
:Experiments on male hybrid mice demonstrated that specific immunotherapy with preparations based on carcinoembryonal antigen and mucin containing CA 125 antigen was not associated with general toxicity, local irritating effect, and hepatorenal dysfunction. The absence of toxicity is apparently due to the fact that antigens injected intramuscularly or subcutaneously virtually do not enter the blood. Injections of preparations based on carcinoembryonal antigen and mucin containing CA 125 antigen to mice induced a standard immune response with predominance of class M immunoglobulins during the early terms and class G immunoglobulins at later terms.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Sitdikova SM,Amandzholov BS,Sel'chuk VY,Kormosh NG,Laktionov KP,Lebedin YS,Chukanov SV,Toptygin AY,Manzyuk LV,Donenko FVdoi
10.1007/BF02439280subject
Has Abstractpub_date
2000-04-01 00:00:00pages
389-91issue
4eissn
0007-4888issn
1573-8221journal_volume
129pub_type
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