Abstract:
:Pro-Gly-Pro and its metabolite Gly-Pro effectively prevented the development of erosive and ulcerative lesions of the gastric mucosa in rats under conditions of water-immersion restraint stress by restoring the oxidatant-antioxidant balance in the total fraction of gastric mucosa cells. Pro-Gly was least effective in this respect. We conclude that glyprolines hold much promise as pharmaceutical products, which can be used in gastroenterological practice for the prevention and therapy of ulcer disease of the stomach and duodenum.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Falalyeyeva TM,Samonina GE,Beregovaya TV,Andreeva LA,Dvorshchenko EVdoi
10.1007/s10517-010-0866-7subject
Has Abstractpub_date
2010-07-01 00:00:00pages
26-8issue
1eissn
0007-4888issn
1573-8221journal_volume
149pub_type
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