Abstract:
:New methods of restriction fragment length polymorphism analysis were developed to distinguish polymorphic variants C190T, G191A, G857A, and 859Del of the NAT2 gene located close to each other.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Nikishina MV,Vavilin VA,Lyakhovich VVdoi
10.1007/s10517-009-0309-5subject
Has Abstractpub_date
2008-10-01 00:00:00pages
420-3issue
4eissn
0007-4888issn
1573-8221journal_volume
146pub_type
杂志文章abstract::Study of the arteriovenous difference in hormone levels and hemostasis parameters in rats with experimental gestosis induced by hyper-sodium diet showed decreased production of progesterone, increased level of hydrocortisone (resultant from its increased production and additional release of the hormone by the lungs), ...
journal_title:Bulletin of experimental biology and medicine
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abstract::Intravenous infection of chicken with H5N1 avian influenza virus (strain A/Gs/Krasnoozerskoye/627/05) causes rapid lethal outcome. Pathomorphological study of bird viscera showed manifestations of disseminated intravascular coagulation syndrome, generalized inflammatory reaction, and wide-scale necrobiotic changes in ...
journal_title:Bulletin of experimental biology and medicine
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doi:10.1007/s10517-009-0376-7
更新日期:2008-12-01 00:00:00
abstract::The author name G. A. Chastikina should read G. A. Chastikin. ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章,已发布勘误
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更新日期:2017-09-01 00:00:00
abstract::We studied a combined effect of subcomponents of vitamin B complex on the growth, development, and death of human embryonic brain-derived cells (E90) cultured using a modified method of Matson. Cell death was detected by trypan blue staining. According to our results, vitamin B-complex in low-doses promote the develop...
journal_title:Bulletin of experimental biology and medicine
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doi:10.1007/s10517-011-1387-8
更新日期:2011-09-01 00:00:00
abstract::The dynamics of LPO marker malondialdehyde formation and peroxidase-destroying activity was studied in homogenized organs of guinea pigs, immunized with thermoextracts from S and L forms Brucella abortus I-206. The L form brucella thermoextract exhibited a lower reactogenicity and adequately activated the antioxidant ...
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doi:10.1007/s10517-018-4138-2
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abstract::Number and size of aggregated lymphoid nodules in the small intestine of mice exposed to radiation using a γ-irradiation unit GOBO-60 with 137Cs source were measured using the methods of visual microscopy and morphometry. Morphological status of the nodules was estimated on days 4, 28, 60, and 90 after the exposure. S...
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更新日期:2017-12-01 00:00:00
abstract::We studied the effect of interleukin-1beta on the behavior of rats with different individual typological characteristics during mild stress in the open-field test. Intraperitoneal injection of interleukin-1beta (5 microg/kg, 108 U/mg) was followed by a decrease in orientation and exploratory activity of passive and, p...
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abstract::We revealed an antimetastatic effect of thymus-dependent corpuscular antigen (sheep erythrocytes) injected intravenously or intraperitoneally in sensitizing or high doses alone or in a complex with a course dose of cyclophosphamide to C57Bl/6 mice with Lewis carcinoma. Injection of the antigen appreciably reduced the ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/b:bebm.0000042717.00428.e9
更新日期:2004-06-01 00:00:00
abstract::The tissue engineering construction was developed from human bone marrow multipotent stromal cells and 3D porous foamed-ceramic carriers of a zirconium oxide-aluminum oxide system. The carriers had no cytotoxic activity and were potent in maintaining the cell adhesion and proliferation. We developed the method for ino...
journal_title:Bulletin of experimental biology and medicine
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abstract::The immunobiological potential of a new microorganism species isolated from permafrost specimens (PMO strain 3M) collected from the Mammoth Mountain in Yakutia was studied in laboratory mice. PMO injected intraperitoneally in doses of 2500 to 50 × 10(6) microbial bodies caused characteristic dose-dependent effects on ...
journal_title:Bulletin of experimental biology and medicine
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doi:10.1007/s10517-011-1289-9
更新日期:2011-06-01 00:00:00
abstract::One-month therapy with trimetazidine sharply decreased the content of free radical oxidation products, lipid peroxides and malonic dialdehyde, in atherogenic low-density lipoproteins in patients with coronary heart disease. Activity of glutathione peroxidase utilizing lipid peroxides in the plasma markedly increased d...
journal_title:Bulletin of experimental biology and medicine
pub_type: 临床试验,杂志文章
doi:
更新日期:2000-10-01 00:00:00
abstract::Comparative analysis of the efficiency of PCR and microbiological methods for deciphering of the etiological structure of non-nosocomial pneumonias demonstrated the diagnostic significance of detecting Streptococcus pneumoniae DNA in the blood, but not sputum. Mechanisms of penetration of S. pneumoniae into the blood ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/b:bebm.0000010969.76881.87
更新日期:2003-10-01 00:00:00
abstract::We studied the expression of genes encoding angiotensinogen (Agt), renin (Ren), angiotensin-converting enzyme (ACE), and type 1 angiotensin receptor (AT1A) in the hypothalamus and medulla oblongata of hypertensive ISIAH rats and normotensive WAG rats. The amount of Agt mRNA in the hypothalamus of young ISIAH rats was ...
journal_title:Bulletin of experimental biology and medicine
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更新日期:2013-01-01 00:00:00
abstract::Plasma LDL content increased in rats with mild chronic heart failure, but decreased in animals with severe pathology. The lipid profile of β-adrenoceptor antagonists depended on their selectivity. The most selective antagonists of β-adrenoceptors had little effect on the lipid composition. Nonselective β-adrenoceptor ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-013-2312-0
更新日期:2013-12-01 00:00:00
abstract::We studied morphological changes in the myocardium during experimental myocardial infarction in rats with different resistance to hypoxia. Microscopic examination showed that morphological changes in the ischemic zone and adjacent tissues are different in rats with high and low resistance to acute ischemia. In highly ...
journal_title:Bulletin of experimental biology and medicine
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abstract::A series of short neurotoxins (molecular weight 3500-5000 D) was isolated from Vietnamese scorpion B. occitanus sp. All these toxins blocked generation of action potentials (this effect depended on their molecular weight), but did not change conduction velocity and excitation threshold of the nerve. ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/a:1013659026064
更新日期:2001-10-01 00:00:00
abstract::Characteristics of distribution of cholinergic and adrenoceptor structures along the sinoatrial node artery in rat heart were evaluated by autoradiography on semithin sections by determining the density of (3)H-dihydroalprenolol and (3)H-quinuclidinyl benzilate binding sites. The relative density of binding sites for ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-005-0420-1
更新日期:2005-07-01 00:00:00
abstract::Parameters of cardiac activity after administration of the cholinesterase inhibitor physostigmine were analyzed in newborn rats and on day 16 of postnatal development. The type of cardiovascular response to acetylcholine excess in newborns and 16-day-old rats were similar, but they significantly differed by the magnit...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-018-4095-9
更新日期:2018-05-01 00:00:00
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journal_title:Bulletin of experimental biology and medicine
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journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
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更新日期:2001-09-01 00:00:00
abstract::Precise location of IL-18 in cell and tissue elements of the atherosclerotic lesions in humans and its role in destabilization of the atherosclerotic plaque were detected. The data suggested a hypothesis on indirect involvement of IL-18 in destruction of the elastic and collagen fibers in an unstable plaque due to thi...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-014-2675-x
更新日期:2014-10-01 00:00:00
abstract::Hemopoietic islets, associations of stromal (macrophages, fibroblasts) and blood (including stem) cells, are structural and functional units of the bone marrow. We studied cellular and molecular processes developing following short-term (1 h) contact of hemopoietic islets with ferromagnetic nanoparticles in a multicel...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-011-1360-6
更新日期:2011-08-01 00:00:00
abstract::We developed wound coating based on natural biopolymer chitosan with additional components (ceruloplasmin, L-asparaginic acid, and glycerol). Experiments on albino male rats demonstrated its regeneratory, antioxidant, and antibacterial effects on wounds involving all layers of the skin. Due to chemical composition and...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
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更新日期:2016-03-01 00:00:00
abstract::In experiments on Wistar rats we studied the effect of low-frequency electromagnetic field rotating in either right-handed or a left-handed sense on proteolytic activity of pepsin. The right-handed rotating field increased, while left-handed rotating field decreased pepsin activity. Possible mechanisms of these change...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-005-0281-7
更新日期:2005-03-01 00:00:00
abstract::We compared the level of transforming growth factor-β1 (TGF-β1) in the tear fluid of 20 patients with high myopia who underwent transepithelial photorefractive keratectomy (T-PRK) in one eye and laser subepithelial keratomileusis (LASEK) in the contralateral eye. Tear fluid samples were collected with scaled microcapi...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
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journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-014-2715-6
更新日期:2014-11-01 00:00:00
abstract::The anti-ischemic effect of synthetic and pharmacologically tested anxiolytic afobazole (10 mg/kg intravenously) was studied on anesthetized rats with acute endocardial ischemia caused by isoproterenol infusion (20 mg/kg/min). A calcium antagonist verapamil (1 mg/kg intravenously) belonging to the group of phenyl alky...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-013-2246-6
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abstract::Tetrapeptide H-Ala-Glu-Asp-Arg-OH enhances the expression of cytoskeletal (actin, tubulin, vimentin) and nuclear matrix proteins (lamin A, lamin C) in cultured mouse embryonic fibroblasts by 2-5 and 2-3 times, respectively. Thus, the previously reported cardioprotective activity of this tetrapeptide is determined by i...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-012-1766-9
更新日期:2012-08-01 00:00:00