Ratio between the number of Th1 and Th2 lymphocytes in the peripheral blood and concentration of proinflammatory cytokines in lochia of women with postpartum endometritis.

Abstract:

:We estimated the percentage of CD4+ lymphocytes synthesizing IFN-gamma and IL-4 in the peripheral blood and measured the concentrations of IL-1, IL-6, and TNF-alpha in lochia of patients with postpartum endometritis. T lymphocytes with intracellular IFN-gamma prevailed in women with physiological course of the postpartum period. The number of cells containing IL-4 increased in patients with postpartum endometritis. On days 5-7 after childbirth the concentrations of proinflammatory cytokines IL-1beta and TNF-alpha in lochia of these patients were higher than in healthy postpartum women (by 1.4 and 2.7 times, respectively). The concentrations of cytokines IL-1beta, TNF-alpha, and IL-6 increased most significantly in patients with postpartum endometritis and active viral infection (by 3.4, 4.2, and 1.6 times, respectively).

journal_name

Bull Exp Biol Med

authors

Sukhikh GT,Kasabulatov NM,Van'ko LV,Ordzhonikidze NV,Veryasov VN,Danelyan SZh

doi

10.1007/s10517-006-0050-2

subject

Has Abstract

pub_date

2005-12-01 00:00:00

pages

672-4

issue

6

eissn

0007-4888

issn

1573-8221

journal_volume

140

pub_type

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