Abstract:
:Dysregulation of neuroimmune connections is a primary or secondary pathogenic factor of some CNS diseases. Autoimmune aggression is typical of multiple sclerosis, Alzheimer's disease, and epilepsy, while dysregulation characterized by enhanced production of autoantibodies to neurotransmitters and activation of cell factors is characteristic of alcoholism and drug abuse. In experimental models of alcoholism and drug addiction, protective effects of antiserotonin antibodies are mediated by immune cells stimulated by these antibodies. These effects can be used in the therapy of various forms of neuroimmunopathology by the method of adoptive immunotherapy.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Evseev VA,Davydova TV,Mikovskaya OIdoi
10.1023/a:1017964229295subject
Has Abstractpub_date
2001-04-01 00:00:00pages
305-8issue
4eissn
0007-4888issn
1573-8221journal_volume
131pub_type
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