Dysregulation in neuroimmunopathology and perspectives of immunotherapy.

Abstract:

:Dysregulation of neuroimmune connections is a primary or secondary pathogenic factor of some CNS diseases. Autoimmune aggression is typical of multiple sclerosis, Alzheimer's disease, and epilepsy, while dysregulation characterized by enhanced production of autoantibodies to neurotransmitters and activation of cell factors is characteristic of alcoholism and drug abuse. In experimental models of alcoholism and drug addiction, protective effects of antiserotonin antibodies are mediated by immune cells stimulated by these antibodies. These effects can be used in the therapy of various forms of neuroimmunopathology by the method of adoptive immunotherapy.

journal_name

Bull Exp Biol Med

authors

Evseev VA,Davydova TV,Mikovskaya OI

doi

10.1023/a:1017964229295

subject

Has Abstract

pub_date

2001-04-01 00:00:00

pages

305-8

issue

4

eissn

0007-4888

issn

1573-8221

journal_volume

131

pub_type

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