Experimental study of the efficiency of oxidized dextran for prevention of influenza A/H5N1.

Abstract:

:Oxidized dextran is suggested for prevention of infection induced by influenza A/H5N1 viruses, methods of its use and doses are determined. Two intravenous injections of dextran 3 and 1 days before experimental infection of outbred mice by influenza A/H5N1 A/goose/Krasnoozerskoye/627/05 virus resulted in a high preventive dose-dependent effect: the mean lifespan was 25% prolonged, the mortality decreased 3-fold.

journal_name

Bull Exp Biol Med

authors

Shkurupy VA,Potapova OV,Sharkova TV,Troitskii AV,Gulyaeva EP,Bystrova TN,Shestopalov AM

doi

10.1007/s10517-014-2704-9

subject

Has Abstract

pub_date

2014-11-01 00:00:00

pages

112-4

issue

1

eissn

0007-4888

issn

1573-8221

journal_volume

158

pub_type

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