Effect of physical training on blood level of endogenous modulators of beta-adreno- and m-cholinoreactivity in patients with a history of myocardial infarction.

abstract：:The effect of panavir on Parkinson's syndrome induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine was studied in C57Bl/6 mice and outbred albino rats. Two injections of panavir significantly reduced the severity of oligokinesia and autonomic manifestations of experimentally induced Parkinson's syndrome. ...

journal_title：Bulletin of experimental biology and medicine

authors： Kalinina TS,Nerobkova LN,Voronina TA,Stovbun SV,Litvin AA,Sergienko VI

更新日期：2005-07-01 00:00:00

abstract：:The dynamics of LPO marker malondialdehyde formation and peroxidase-destroying activity was studied in homogenized organs of guinea pigs, immunized with thermoextracts from S and L forms Brucella abortus I-206. The L form brucella thermoextract exhibited a lower reactogenicity and adequately activated the antioxidant ...

journal_title：Bulletin of experimental biology and medicine

authors： Dubrovina VI,Balakhonov SV,Yurieva OV,Starovoitova TP,Barannikova NL,Tokareva LE,Pyatidesyatnikova AB,Yastremskaya KY,Shkaruba TT

更新日期：2018-06-01 00:00:00

abstract：:The concentrations of the key factors of molecular pathogenesis of prehypertension (angiotensin II, HLDF24, S100b, endothelin, autoantibodies to these molecules, and VEGF) were analyzed in subjects with optimal BP (<120/80 mm Hg) and prehypertension (120-139/80-89 mm Hg). Comparative and correlation analysis of the le...

journal_title：Bulletin of experimental biology and medicine

authors： Sherstnev VV,Gruden MA,Karlina VP,Ryzhov VM,Kuznetsova AV,Senko OV

更新日期：2020-01-01 00:00:00

abstract：:We propose a method of creation of a 3D matrix consisting of native collagen fibers and natural polysaccharide chitosan. The collagen-chitosan hydrogels maintain viability and prolipherative activity of embryonic stem cells obtained from internal cells of mouse blastocyst. The proposed system forming hydrogels in situ...

journal_title：Bulletin of experimental biology and medicine

authors： Selezneva II,Savintseva IV,Vikhlyantseva EF,Davydova GA,Gavrilyuk BK

更新日期：2006-07-01 00:00:00

abstract：:We studied the effects of stress exposure during the adolescent period of development (SAPD) on the parameters of inflammatory painful response and the level of depression-like behavior in prenatally stressed adult male rats. In addition, we analyzed the effects of selective serotonin (5-HT) reuptake inhibitor fluoxet...

journal_title：Bulletin of experimental biology and medicine

authors： Butkevich IP,Mikhailenko VA

更新日期：2020-07-01 00:00:00

abstract：:We performed a comparative study of the localization, distribution, metabolic activity, and surface properties of human bone marrow mesenchymal stromal cells after static and perfusion seeding to macroporous alginate cryogels. A simple perfusion system for mesenchymal stromal cell seeding to macroporous alginate cryog...

journal_title：Bulletin of experimental biology and medicine

authors： Petrenko YA,Ivanov RV,Lozinsky VI,Petrenko AY

更新日期：2011-02-01 00:00:00

abstract：:Fifty-three transplantations of pituitary tissue (intact and minced with scissors) under the tunica albuginea testis were carried out. In both series pituitary cells retained viability for up to 6 months. Transplantation of cell suspension was not accompanied by the formation of necrotic zone in the transplant; the ad...

journal_title：Bulletin of experimental biology and medicine

authors： Dendeberov ES

更新日期：2001-02-01 00:00:00

abstract：:Electron microscopic study of changes in cultured cells caused by Vibrio cholerae recombinant hemagglutinin/protease (HA/P) showed significant structural changes, most pronounced in HeLa and L-929 cells not forming a compact monolayer with tight junctions between the cells: formation of numerous vesicles on the cell s...

journal_title：Bulletin of experimental biology and medicine

authors： Sayamov SR,Monakhova EV,Fedorenko GM,Tkacheva TI,Markina OV,Alekseeva LP,Pisanov RV,Bardakhchian EA

更新日期：2012-02-01 00:00:00

abstract：:Individual or combined administration of BCG vaccine and silicon dioxide to male mice induced a nonspecific stress response of the adrenal glands and gonads judging from changes in the concentration of blood cortisol and testosterone. The dynamics of cortisol concentration in the adrenal glands was similar, while chan...

journal_title：Bulletin of experimental biology and medicine

authors： Palchikova NA,Kuzminova OI,Utkina NV,Selyatitskaya VG,Shkurupiy VA

更新日期：2008-12-01 00:00:00

abstract：:Drug resistance and viability of Mycobacterium tuberculosis were studied in 637 patients with pulmonary tuberculosis, detected by screening fluorography (group 1) and in 909 patients in whom the specific process was detected when they applied for medical care (group 2). The mycobacteria in the two groups did not diffe...

journal_title：Bulletin of experimental biology and medicine

authors： Koretskaya NM,Narkevich AN

更新日期：2014-11-01 00:00:00

abstract：:Comparative analysis of proteoglycans in the control and tumor tissue of human mammary gland revealed disorders in the biosynthesis of dermatan sulfate proteoglycans in tumor cells. Using the methods of reverse transcription-PCR and Western blotting for the analysis of decorin expression we showed that these disorders...

journal_title：Bulletin of experimental biology and medicine

authors： Rykova VI,Grigorieva EV,Chernenko AV,Eshenko TY,Dymshits GM

更新日期：2007-09-01 00:00:00

abstract：:Human recombinant erythropoietin adsorbed on poly(butyl)cyanoacrylate nanoparticles and administered intraperitoneally in a dose of 0.05 mg/kg exhibited a neuroprotective effect in experimental intracerebral posttraumatic hematomas (hemorrhagic stroke) and reduced animal mortality. Human recombinant erythropoietin, na...

journal_title：Bulletin of experimental biology and medicine

authors： Solev IN,Balabanyan VY,Volchek IA,Elizarova OS,Litvinova SA,Garibova TL,Voronina TA

更新日期：2013-06-01 00:00:00

abstract：:The significance of neurospecific proteins in the diagnosis of neurotoxicity in patients with breast, lung, testicular, and ovarian cancer treated by taxane and cisplatin drugs was evaluated. The most pronounced increase in the content of these proteins and titers of autoantibodies to these proteins was observed in pa...

journal_title：Bulletin of experimental biology and medicine

authors： Lyubimova NV,Toms MG,Shakirova IN,Gurina OI,Kushlinskii NE

更新日期：2001-11-01 00:00:00

abstract：:The immunobiological potential of a new microorganism species isolated from permafrost specimens (PMO strain 3M) collected from the Mammoth Mountain in Yakutia was studied in laboratory mice. PMO injected intraperitoneally in doses of 2500 to 50 × 10(6) microbial bodies caused characteristic dose-dependent effects on ...

journal_title：Bulletin of experimental biology and medicine

authors： Kalenova LF,Suhovey UG,Broushkov AV,Melnikov VP,Fisher TA,Besedin IM,Novikova MA,Efimova JA,Subbotin AM

更新日期：2011-06-01 00:00:00

abstract：:Intranigral administration of glutamate to rats with parkinsonian syndrome induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine augmented the development of parkinsonian symptoms (oligokinesia and muscular rigidity), but did not affect motor activity of intact animals. Memantine administered intraperitoneally in pa...

journal_title：Bulletin of experimental biology and medicine

authors： Kucheryanu VG,Kryzhanovskii GN

更新日期：2000-07-01 00:00:00

abstract：:The rats with neurodegenerative brain disorder induced by administration of a toxic fragment of beta-amyloid demonstrate weakened endothelium-dependent dilation of cerebral vessels, which attested to impaired production of endothelial NO. At the same time, toxic beta-amyloid fragment induced the formation of NO depots...

journal_title：Bulletin of experimental biology and medicine

authors： Mashina SY,Aleksandrin VV,Goryacheva AV,Vlasova MA,Vanin AF,Malyshev IY,Manukhina EB

更新日期：2006-08-01 00:00:00

abstract：:The study was undertaken to determine the mechanism of carnosine effect on cell proliferation. We studied the effect of carnosine and its derivatives on cell cycle progression in cultured rat pheochromocytoma cells (PC-12). It was found that 48-h incubation of PC-12 cells with carnosine in concentrations of 10-50 mM l...

journal_title：Bulletin of experimental biology and medicine

authors： Rybakova YS,Boldyrev AA

更新日期：2012-11-01 00:00:00

abstract：:Forty patients with severe asthenia were subjected to clinical, neurological, psychometric, and neurophysiologic examination before and after Enerion therapy. Psychoneurophysiological assessment with cognitive evoked potentials P300 and psychometric tests revealed serious impairment of cognitive functions in patients ...

journal_title：Bulletin of experimental biology and medicine

authors： Gordeev SA,Fedotova AV,Vein AM

更新日期：2003-11-01 00:00:00

abstract：:Morphological changes in the mesenteric lymph nodes of male C57Bl/6 mice and subpopulation composition of lymphocytes in these nodes were studied in experimental acute and chronic ulcerative colitis induced by sodium dextran sulfate. Acute and chronic ulcerative colitis was associated with the development of reactive ...

journal_title：Bulletin of experimental biology and medicine

authors： Postovalova EA,Khochansky DN,Zolotova NA,Gao Y,Makarova OV,Dobrynina MT

更新日期：2016-04-01 00:00:00

abstract：:JAK/STAT signaling pathway was examined comparatively during realization of growth potential of mesenchymal progenitor cells stimulated with diterpene alkaloid songorine or fibroblast growth factor. The stimulating role of JAKs and STAT3 on the mitotic activity and differentiation of progenitor cells cultured with son...

journal_title：Bulletin of experimental biology and medicine

authors： Zyuz'kov GN,Udut EV,Miroshnichenko LA,Polyakova TY,Simanina EV,Stavrova LA,Prosekin GA,Zhdanov VV,Udut VV

更新日期：2018-09-01 00:00:00

abstract：:Cytochrome p450-mediated metabolism of GRS (indolinone antiaggregant) and its effects on activities of cytochrome p450 isoenzymes were studied. Inhibition of 6 isomers of cytochrome p450 in human liver microsomes was studied with the use of specific substrates. It was found that human liver cytochrome p450 enzymes cou...

journal_title：Bulletin of experimental biology and medicine

authors： Bykov VV,Leonov KA,Serebrov VY,Chernysheva GA,Smol'yakova VI,Solov'ev MA,Udut EV,Fisenko VP,Udut VV

更新日期：2020-04-01 00:00:00

abstract：:Consumption of low dose DDT from birth until puberty suppressed functional activity of the thyroid gland in rats and leads to destructive changes in the organ during the postpubertal period with compensatory stimulation of secretory activity of thyrocytes aimed at normalization of thyroxin production. ...

journal_title：Bulletin of experimental biology and medicine

authors： Yaglova NV,Sledneva YP,Yaglov VV

更新日期：2016-12-01 00:00:00

abstract：:We studied properties of bacterial biofilms during long-term culturing. The biofilms were preserved for more than 90 days under the chosen conditions. At the same time, amounts of matrix and cells underwent periodic changes. The biomass of the biofilms decreased approximately every 7 days and then returned to the prev...

journal_title：Bulletin of experimental biology and medicine

authors： Tetz GV,Artemenko NK,Zaslavskaya NV,Tetz VV

更新日期：2013-08-01 00:00:00

abstract：:We demonstrate changes in cellular and humoral immunity in animals with experimental hyperthyroidism induced by chronic administration of potassium iodide (KI) solution. KI increased the weight and cellularity of the thymus and spleen and number of antibody-forming cells to sheep red blood cells and modified the relat...

journal_title：Bulletin of experimental biology and medicine

authors： Robinson MV,Obut TA,Melnikova EV,Trufakin VA

更新日期：2014-02-01 00:00:00

abstract：:Intraperitoneal injection of Semax (synthetic analogue of ACTH4-7, MEHFPGP) in a dose of 50 mg/kg produced a protective effect on rats with experimental indomethacin-induced ulcers. Experiments on narcotized rats showed that Semax in the studied dose had no effect on basal blood flow in the stomach, but prevented redu...

journal_title：Bulletin of experimental biology and medicine

authors： Zhuikova SE,Sergeev VI,Samonina GE,Myasoedov NF

更新日期：2002-06-01 00:00:00

abstract：:Pronounced changes in the capillaries, hemodynamic disorders, epitheliocyte degeneration and atrophy develop in the buccal mucosa of patients with types I and II diabetes mellitus in the absence of inflammatory cellular infiltration or with facultative infiltration. The morphogenesis of pathological changes can be reg...

journal_title：Bulletin of experimental biology and medicine

authors： Balakhonov LV,Nepomnyashchikh LM,Aidagulova SV,Bakarev MA,Vlasova LF

更新日期：2006-11-01 00:00:00

abstract：:The development of MPTP-induced depressive syndrome in rats was accompanied by activation of prolyl endopeptidase and dipeptidyl peptidase IV in the brain frontal cortex. Prolyl endopeptidase activity in the striatum also increased under these conditions. Our results indicate that proline-specific peptidases in the ta...

journal_title：Bulletin of experimental biology and medicine

authors： Krupina NA,Zolotov NN,Bogdanova NG,Orlova IN,Khlebnikova NN,Kryzhanovskii GN

更新日期：2006-11-01 00:00:00

abstract：:Low-dose (250 mg daily) oral probucol produces a significant antioxidant effect in coronary patients: increases activity of glutathione peroxidase (enzyme utilizing lipoperoxides) and reduces the content of free-radical oxidation products in the blood. Probucol therapy for 7 days before and for 6 months after coronary...

journal_title：Bulletin of experimental biology and medicine

authors： Kaminnyi AI,Lankin VZ,Perepelitsa EI,Konovalova GG,Samko AN,Tikhaze AK,Kukharchuk VV,Belenkov YN

更新日期：2007-11-01 00:00:00

abstract：:A combination of electrochemical lysis and photodynamic therapy were used to attain complete resorption of M-1 sarcoma in rats; both treatment modalities were used with minimum parameters. Fotolon served as the photosensitizer for photodynamic therapy. Accumulation of the sensitizer in the tumor and normal tissue was ...

journal_title：Bulletin of experimental biology and medicine

authors： Mikhailovskaya AA,Kaplan MA,Brodskij RA,Bandurko LN

更新日期：2009-01-01 00:00:00

abstract：:C57Bl/6 mice were intranasally infected with influenza virus A/H5N1 A/goose/Krasnoozerskoye/627/05. The mortality rate of animals reached 70% on day 14 of the disease. The lungs of animals were characterized by necroses, destruction of vessels, hemorrhagic and thrombotic complications, edematous syndrome, and early fi...

journal_title：Bulletin of experimental biology and medicine

authors： Kovner AV,Anikina AG,Potapova OV,Sharkova TV,Cherdanceva LA,Shkurupy VA,Shestopalov AM

更新日期：2012-06-01 00:00:00