Effects of Thermoextracts of Brucella S and L Forms on Lipid Peroxidation and Antioxidant Defense in Organs of Laboratory Animals.

abstract：:The effects of ladasten and reference product imipramine (10 mg/kg) on the content of cytokines TNF-α, IL-6, IL-10, IL-1α, IL-2, IL-4, IL-5, IL-17, IFN-γ, and GM-CSF and behavior of male C57Bl/6 mice were studied on the model of a depression-like state induced by a single intraperitoneal injection of bacterial LPS in ...

journal_title：Bulletin of experimental biology and medicine

authors： Tallerova AV,Kovalenko LP,Durnev AD,Seredenin SB

更新日期：2011-11-01 00:00:00

abstract：:Sulfamide-resistant (SulR) natural strains of enterobacteria (11.9% of a total of 797 cultures, isolated with enteric microflora of honeybee gut, bee-fermented pollen, and plant issues) were tested for class 1 antibiotic resistance integrons (MRI). Only 5.3% of SulR strains were MRI-positive. Mutability of weak (wild ...

journal_title：Bulletin of experimental biology and medicine

authors： Solomenny AP,Lyapunov YE,Kuzyaev RZ

更新日期：2011-09-01 00:00:00

abstract：:In rat sinoatrial node, NAD(+) (10 μM) reduced the rate of spontaneous action potentials, duration of action potentials, and the velocity of slow diastolic depolarization, but the rate of action potential front propagation increases. In passed rabbit Purkinje fibers, NAD(+) (10 μM) reduced the duration of action poten...

journal_title：Bulletin of experimental biology and medicine

authors： Pustovit KB,Kuz'min VS,Sukhova GS

更新日期：2015-06-01 00:00:00

abstract：:Influenza virus hemagglutinins are surface proteins responsible for fusion of the viral and cellular membranes. Their capacity to mediate membrane fusion (fusogenic activity) is studied by various methods, including the syncytium formation and pseudovirus transduction methods. We constructed plasmids coding for genes ...

journal_title：Bulletin of experimental biology and medicine

authors： Kononova AA,Cheresiz SV,Chechushkov AV,Razumova YV,Pokrovskii AG

更新日期：2017-11-01 00:00:00

abstract：:The development of experimental type II diabetes mellitus in rats was accompanied by dysfunction of inhibitory and stimulatory heterotrimeric G-proteins, components of hormone-sensitive adenylate cyclase signal system. The function of inhibitory G-proteins decreased most significantly under these conditions, which is ...

journal_title：Bulletin of experimental biology and medicine

authors： Shpakov AO,Kuznetsova LA,Plesneva SA,Bondareva VM,Guryanov IA,Vlasov GP,Pertseva MN

更新日期：2006-12-01 00:00:00

abstract：:We performed morphofunctional analysis of cultured rabbit buccal epithelial cells in the primary culture, during passaging, and upon interaction with collagen substrates. Three different morphological types were identified. It was demonstrated that precursors of rabbit buccal epithelium were characterized by high prol...

journal_title：Bulletin of experimental biology and medicine

authors： Chentsova EV,Konyushko OI,Makarov MS,Egorova NS,Zinov'ev MY,Borovkova NV

更新日期：2015-05-01 00:00:00

abstract：:We studied the effects of optical (dd-, ll-, dl-, and ld-dipeptides with alpha-bond, EW) structural isomers and cyclic (dd-, ll-, dl-, and ld-dipeptides with gamma-bond, iEW) analogs of Glu-Trp synthetic dipeptide on the population of normal hemopoietic stem cells. Dipeptides containing lGlu (lGlu-lTrp, lGlu-dTrp) inj...

journal_title：Bulletin of experimental biology and medicine

authors： Semina OV,Semenets TN,Zamulaeva IA,Selivanova EI,Malyutina YV,Saenko AS,Deigin VI

更新日期：2006-02-01 00:00:00

abstract：:The rats with neurodegenerative brain disorder induced by administration of a toxic fragment of beta-amyloid demonstrate weakened endothelium-dependent dilation of cerebral vessels, which attested to impaired production of endothelial NO. At the same time, toxic beta-amyloid fragment induced the formation of NO depots...

journal_title：Bulletin of experimental biology and medicine

authors： Mashina SY,Aleksandrin VV,Goryacheva AV,Vlasova MA,Vanin AF,Malyshev IY,Manukhina EB

更新日期：2006-08-01 00:00:00

abstract：:Function of sarcoplasmic reticulum was studied in rat papillary muscles treated with amiodarone. An extra stimulus (0.5 Hz) was delivered to the muscle 0.225 sec after application of a regular stimulus. Postextrasystolic potentiation was evaluated in control myocardial samples and samples treated with amiodarone. The ...

journal_title：Bulletin of experimental biology and medicine

authors： Afanas'ev SA,Lukavskaya IA,Kandinskii ML,Medvedev MA

更新日期：2002-03-01 00:00:00

abstract：:The appearance of autoantibodies to neuronal proteins (S100, GFAP, MBP, and NGF) in rat serum was analyzed by ELISA on days 5, 10, 17, 25, and 32 after streptozotocin injection. Simultaneously, blood glucose and insulin autoantibodies were assayed. Serum glucose level increased on the next day after streptozotocin inj...

journal_title：Bulletin of experimental biology and medicine

authors： Lotosh NG,Savel'eva EK,Selishcheva AA,Savel'ev SV

更新日期：2013-05-01 00:00:00

abstract：:We studied the phospholipid composition of high-density lipoproteins in patients with hypercholesterolemia before and after treatment with simvastatin. Individual phospholipids were separated by thin-layer chromatography on glass plates coated with silica gel. It was found that apart from hypolipidemic effect, simvast...

journal_title：Bulletin of experimental biology and medicine

authors： Ozerova IN,Paramonova IV,Olfer'ev AM,Akhmedzhanov NM,Aleksandrova MA,Perova NV

更新日期：2001-08-01 00:00:00

abstract：:Behavioral responses of 90-day-old male offspring from female Wistar rats exposed to restraint stress during the last week of pregnancy were studied in the formalin test. Specific biphasic behavioral response characterized acute (phase 1) and persistent tonic pain (phase 2). The intensity of nociceptive responses (eva...

journal_title：Bulletin of experimental biology and medicine

authors： Butkevich IP

更新日期：2002-02-01 00:00:00

abstract：:Chinese hamster cells in culture were blocked in prometaphase by the addition of chloral hydrate. After 2 h the chloral hydrate was removed and the ultrastructural changes in the kinetochore studied during recovery of mitosis. The kinetochore in the blocked cells is a disc measuring 300-350 nm in diameter and 30-35 nm...

journal_title：Bulletin of experimental biology and medicine

authors： Alov IA,Lyubskii SL

更新日期：1975-01-01 00:00:00

abstract：:Electron microscopic study of changes in cultured cells caused by Vibrio cholerae recombinant hemagglutinin/protease (HA/P) showed significant structural changes, most pronounced in HeLa and L-929 cells not forming a compact monolayer with tight junctions between the cells: formation of numerous vesicles on the cell s...

journal_title：Bulletin of experimental biology and medicine

authors： Sayamov SR,Monakhova EV,Fedorenko GM,Tkacheva TI,Markina OV,Alekseeva LP,Pisanov RV,Bardakhchian EA

更新日期：2012-02-01 00:00:00

abstract：:The effects of opioids (morphine and fentanyl) on the function of mechanoreceptive respiration regulatory loop were demonstrated. In most opioid-treated rats (74% cases) vagotomy was followed by apneustic respiration with inspiration pause. Excess of opioids in rat CNS produced minor disturbances in the respiration rh...

journal_title：Bulletin of experimental biology and medicine

authors： Tarakanov IA,Tikhomirova LN,Safonov VA

更新日期：2005-04-01 00:00:00

abstract：:A new chromatographic procedure is proposed for rapid (35 min) complete fractionation of flavonoids in plant raw material; the method well discriminates between components with antioxidant activity (rutin, apigenin, quercetin, hesperidin). The method is based on reverse-phase high performance liquid chromatography usi...

journal_title：Bulletin of experimental biology and medicine

authors： Markaryan AA

更新日期：2006-06-01 00:00:00

abstract：:Experiments on male and female CC57BR/Mv mice differing by the sensitivity to carcinogenic effect of urethane on the lungs showed that castration 1 week before carcinogen challenge reduced the number of lung adenomas caused by it in males and somewhat increased the number of tumors in females. Exogenous testosterone a...

journal_title：Bulletin of experimental biology and medicine

authors： Morozkova TS,Kaledin VI

更新日期：2015-10-01 00:00:00

abstract：:Age-related development of behavioral disorders in transgenic mice with modeled Alzheimer's disease carrying V6S3-Tg(APP695)85Dbo Tg(PSENI)85Dbo) genotype was assessed at the age of 7.5, 10 and 20 months in the following tests: open-field, plus maze, T-maze, conditioned passive avoidance response, rotarod, conflict si...

journal_title：Bulletin of experimental biology and medicine

authors： Semina II,Baichurina AZ,Makarova EA,Leushina AV,Kazakevich ZhV,Gabdrakhmanova MR,Mukhamed'yarov MA,Zefirov AL

更新日期：2015-03-01 00:00:00

abstract：:The effect of a 40-day toluene inhalation on learning of young and adult rats was examined in a multi-branched maze. Experimental rats of both age groups needed more time to pass the maze and made more errors than controls. This impairment was observed in young rats immediately after termination of toluene inhalation ...

journal_title：Bulletin of experimental biology and medicine

authors： Bikashvili TZ,Chilachava LR,Gelazonia LK,Japaridze NJ,Zhvania MG,Lordkipanidze TG,Okuneva VG

更新日期：2012-03-01 00:00:00

abstract：:The effects of intramuscular administration of neostigmine and physostigmine on Na+,K+-ATPase activity in various cerebral subdivisions were examined in rats. In CNS and peripheral tissues, both agents rapidly and significantly reduced activity of cholinesterases by 30-50%. The development of intoxication did not chan...

journal_title：Bulletin of experimental biology and medicine

authors： Dubrovskii VN,Shalabodov AD,Belkin AV

更新日期：2018-11-01 00:00:00

abstract：:Using the experimental model of post-traumatic stress disorder (stress-restress paradigm), we studied the dynamics of activity of the hypothalamic-pituitary-adrenal system (HPAS) in adult male rats, whose mothers were daily subjected to restraint stress on days 15-19 of pregnancy. Prenatally stressed males that were s...

journal_title：Bulletin of experimental biology and medicine

authors： Pivina SG,Rakitskaya VV,Akulova VK,Ordyan NE

更新日期：2016-03-01 00:00:00

abstract：:Significant associations between clinical history factors, lipid metabolism parameters, and type of atherosclerotic process (area of vascular lesions and severity of clinical manifestations) were detected. The predominance of generalized atherosclerosis in chronic coronary heart disease group was associated with patie...

journal_title：Bulletin of experimental biology and medicine

authors： Bakarev MA,Karpova AA,Pichigin VI,Nikityuk DB,Lushnikova EL

更新日期：2016-12-01 00:00:00

abstract：:The third author's name should read: V. V. Matchkov. ...

journal_title：Bulletin of experimental biology and medicine

authors： Kravtsova VV,Bouzinova EV,Matchkov VV,Timonina NA,Zakyrjanova GF,Zefirov AL,Krivoi II

更新日期：2019-05-01 00:00:00

abstract：:Effect of afobazole on the threshold of electrical fibrillation of the heart was studied on anesthetized rats with intact myocardium. It was shown that the drug considerably increased the threshold of electrical fibrillation of the heart, being not inferior to reference class I antiarrhythmic drugs (lidocaine and proc...

journal_title：Bulletin of experimental biology and medicine

authors： Kryzhanovskyi SA,Stolyaruck VN,Vititnova MB,Tsorin IB,Seredenin SB

更新日期：2010-09-01 00:00:00

abstract：:We revealed some relationships between the level of orientation and exploratory behavior, functional activity of the immune system, and structural and functional organization of the CNS in animals. Significant differences in brain morphology and expression of cytokine IL-1 beta, type I IL-1 receptor, and erythropoieti...

journal_title：Bulletin of experimental biology and medicine

authors： Markova EV,Chernova TG,Fillimonov PN,Korotkova NA,Abramov VV,Kozlov VA

更新日期：2004-10-01 00:00:00

abstract：:Taurine is an important endogenous agonist of glycine receptors (GlyR). Using the patchclamp technique, we measured chloride current induced by a short (600 msec) application of taurine (ITau) on isolated rat pyramidal neurons. pH of taurine solution in the applicator pipette was neutral (7.4) or acidic (7.0-5.0). App...

journal_title：Bulletin of experimental biology and medicine

authors： Solntseva EI,Bukanova YV,Kondratenko RV,Skrebitsky VG

更新日期：2019-06-01 00:00:00

abstract：:Experiments on cultured peritoneal macrophage from mice with HA-1 ascitic hepatoma showed that plasma lipoproteins present in the incubation medium decreased intracellular concentration of interleukin-1beta. These changes were most pronounced for high-density lipoproteins (alone or in combination with cortisol). Bacte...

journal_title：Bulletin of experimental biology and medicine

authors： Polyakov LM,Sumenkova DV,Panin LE

更新日期：2009-04-01 00:00:00

abstract：:We studied the interaction between the sympathetic and parasympathetic parts of the autonomic nervous system in the regulation of smooth muscles in the femoral artery and trachea. It was shown that this regulation involves ganglionic serotoninergic neurons transmitting excitation to 5-HT, receptors in the effector tis...

journal_title：Bulletin of experimental biology and medicine

authors： Lazebnik LB,Lychkova AE

更新日期：2006-01-01 00:00:00

abstract：:The prooxidant-antioxidant balance in rats with oxidative stress was studied during correction of the L-arginine-NO system. Oxidative stress was induced by intravenous injection of E. coli lipopolysaccharide. Under conditions of oxidative stress the prooxidant-antioxidant imbalance was least pronounced during selectiv...

journal_title：Bulletin of experimental biology and medicine

authors： Glebov AN,Zinchuk VV

更新日期：2006-04-01 00:00:00

abstract：:The fate of human fetal stem/progenitor cells transplanted into rat brain depends on conditions of preculturing (long or short) and state and site of transplantation. Human nestin-positive stem cells cultured according to the short protocol did not migrate into hypoxic and normal brain after transplantation, but activ...

journal_title：Bulletin of experimental biology and medicine

authors： Revishchin AV,Aleksandrova MA,Podgornyi OV,Marei MV,Poltavtseva RA,Korochkin LI,Stepanov GA,Sukhikh GT

更新日期：2005-02-01 00:00:00