Abstract：
:In rat sinoatrial node, NAD(+) (10 μM) reduced the rate of spontaneous action potentials, duration of action potentials, and the velocity of slow diastolic depolarization, but the rate of action potential front propagation increases. In passed rabbit Purkinje fibers, NAD(+) (10 μM) reduced the duration of action potentials. Under conditions of spontaneous activity of Purkinje fibers, NAD(+) reduced the fi ring rate and the rate of slow diastolic depolarization. The effects of extracellular NAD(+) on bioelectric activity of the pacemaker (sinoatrial node) and conduction system of the heart (Purkinje fibers) are probably related to activation of P1 and P2 purinoceptors.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Pustovit KB,Kuz'min VS,Sukhova GSdoi
10.1007/s10517-015-2919-4subject
Has Abstractpub_date
2015-06-01 00:00:00pages
188-91issue
2eissn
0007-4888issn
1573-8221journal_volume
159pub_type
杂志文章abstract：:We studied the effect of carbon monoxide (60-, 75-, and 90-min exposure) on the expression of antiapoptotic proteins (survivin and Bcl-2) in human blood lymphocytes in the presence of recombinant IL-2 in an apoptosis-inducing dose (0.1 ng/ml). Incubation of cells in atmosphere with carbon monoxide in the presence of r...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-017-3616-2
更新日期：2017-01-01 00:00:00
abstract：:Study of the expression of type IV collagen by Lewis pulmonary carcinoma cells (PLMG-T, PLMG-M1, PLMG-M2) showed that these cells produce type IV collagen. The expression of type IV collagen in PLMG-T and PLMG-M2 cells approximately 2-fold surpassed that in PLMG-M1 cells. The number of active cells (synthesizing type ...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1023/b:bebm.0000024390.08829.ee
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abstract：:Structural reorganization of the myocardium was studied in rats of various age groups (periods of progressive and regressive growth) with anthracycline-induced regenerative and plastic insufficiency. The specific features included the prevalence of cardiomyocyte lysis, diffuse and microfocal changes, and diffuse or mi...
journal_title：Bulletin of experimental biology and medicine
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doi：10.1007/s10517-010-0855-x
更新日期：2009-12-01 00:00:00
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journal_title：Bulletin of experimental biology and medicine
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更新日期：2004-04-01 00:00:00
abstract：:Muramyl dipeptide β-heptylglycoside (C7MDP) was administered to non-pregnant CBA female mice and pregnant mice after non-abortion-prone mating (CBA×BALB/c) and mating associated with a high rate of spontaneous abortion (CBA×DBA/2). In non-pregnant females, C7MDP increased the production of IL-2, IL-4, IL-5, IL-6, IL-1...
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journal_title：Bulletin of experimental biology and medicine
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更新日期：2006-02-01 00:00:00
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journal_title：Bulletin of experimental biology and medicine
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更新日期：2006-01-01 00:00:00
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doi：10.1007/s10517-014-2546-5
更新日期：2014-06-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/s10517-006-0357-z
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journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-015-2821-0
更新日期：2015-03-01 00:00:00
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journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-013-1950-6
更新日期：2013-01-01 00:00:00
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journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-016-3153-4
更新日期：2016-01-01 00:00:00
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journal_title：Bulletin of experimental biology and medicine
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journal_title：Bulletin of experimental biology and medicine
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pub_type： 杂志文章
doi：10.1007/s10517-017-3754-6
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journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-013-2226-x
更新日期：2013-09-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
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更新日期：2017-05-01 00:00:00
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journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-013-2322-y
更新日期：2013-12-01 00:00:00
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journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-015-2904-y
更新日期：2015-05-01 00:00:00
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journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1023/a:1026068208764
更新日期：2003-07-01 00:00:00
