Human fetal neural stem cells in rat brain: effects of preculturing and transplantation.

abstract：:Isolated rat hearts were subjected to 30-min coronary artery occlusion followed by 120-min reperfusion. The hearts (n=8-12) were perfused with Krebs-Henseleit solution enriched with L-carnitine (0.5, 2.5 and 5 mM) for 10 min before and after ischemia or reperfusion and for the whole period of ischemia and reperfusion....

journal_title：Bulletin of experimental biology and medicine

authors： Najafi M,Garjani A,Maleki N,Eteraf Oskouei T

更新日期：2008-08-01 00:00:00

abstract：:The effects of melatonin, aluminum oxide, and polymethylsiloxane complex on the expression of LYVE-1 (lymphatic vessel endothelial hyaluronan receptor) in the liver were studied in db/db mice with experimental obesity and type 2 diabetes mellitus. The complex or placebo was administered daily by gavage from week 8 to ...

journal_title：Bulletin of experimental biology and medicine

authors： Michurina SV,Ishchenko IY,Arkhipov SA,Klimontov VV,Rachkovskaya LN,Konenkov VI,Zavyalov EL

更新日期：2016-12-01 00:00:00

abstract：:The appearance of autoantibodies to neuronal proteins (S100, GFAP, MBP, and NGF) in rat serum was analyzed by ELISA on days 5, 10, 17, 25, and 32 after streptozotocin injection. Simultaneously, blood glucose and insulin autoantibodies were assayed. Serum glucose level increased on the next day after streptozotocin inj...

journal_title：Bulletin of experimental biology and medicine

authors： Lotosh NG,Savel'eva EK,Selishcheva AA,Savel'ev SV

更新日期：2013-05-01 00:00:00

abstract：:We studied the structure of rhythms of BP, HR (by telemetric monitoring), electrolyte excretion (by capillary electrophoresis), and products of epiphyseal melatonin (by the urinary concentration of 6-sulfatoxymelatonin measured by ELISA) in normotensive Wistar-Kyoto rats and spontaneously hypertensive SHR rats maintai...

journal_title：Bulletin of experimental biology and medicine

authors： Blagonravov ML,Bryk AA,Medvedeva EV,Goryachev VA,Chibisov SM,Kurlaeva AO,Agafonov ED

更新日期：2019-11-01 00:00:00

abstract：:Activities of antioxidant enzymes, vitamin E level, lactate dehydrogenase isoenzyme spectrum, and effects of melatonin on these parameters were studied in the myocardium of rats aged 6, 12, 18, and 24 months exposed to different illumination regimens. The greatest number of changes was recorded in rats exposed to perm...

journal_title：Bulletin of experimental biology and medicine

authors： Khizhkin EA,Ilukha VA,Ilyina TN,Unzhakov AR,Vinogradova IA,Anisimov VN

更新日期：2010-09-01 00:00:00

abstract：:The effect of Dicarbamin preparation on hemopoiesis suppressed with cyclophosphamide was studied in animal experiments. It was shown that Dicarbamin produced a protective effect on granulocytic hemopoietic steam. This property of the preparation is determined by both protection of immature granulocytic cells at early ...

journal_title：Bulletin of experimental biology and medicine

authors： Nebolsin VE,Zhdanov VV,Zyuzkov GN,Udut EV,Khrichkova TY,Simanina EV,Stavrova LA,Miroshnichenko LA,Chaikovskiy AV,Dygai AM

更新日期：2011-01-01 00:00:00

abstract：:The incidence of mutations in the BRCA1 and BRCA2 genes in the studied sampling of 74 patients with ovarian cancer was 19%. The incidence of mutations in the Russian sampling of patients, formed without consideration for the family history, is one of the highest in European countries. Retrospective analysis showed tha...

journal_title：Bulletin of experimental biology and medicine

authors： Smirnova TY,Pospekhova NI,Lyubchenko LN,Tjulandin SA,Gar'kavtseva RF,Ginter EK,Karpukhin AV

更新日期：2007-07-01 00:00:00

abstract：:We studied the effect of melatonin (10 mg/kg intraperitoneally) on behavioral indexes reflecting changes in nociceptive sensitivity of rats in response to thermal stimulation in the hot plate test. Administration of melatonin to animals suppressed the perceptual component of nociception, which was manifested in an inc...

journal_title：Bulletin of experimental biology and medicine

authors： Zhuravlev BV,Murtazina EP,Pertsov SS

更新日期：2015-12-01 00:00:00

abstract：:A new phenomenon (or paradox) consisting in higher statistical stability of samples, for example, tremorograms, in a group of different subjects than in the same subject in unchanged homeostasis. At the same time, it turns out that 15 different subjects are more similar (statistically) to each other than one person to...

journal_title：Bulletin of experimental biology and medicine

authors： Zilov VG,Khadartsev AA,Eskov VM,Ilyashenko LK

更新日期：2019-08-01 00:00:00

abstract：:Treatment with a combination of artrofoon and anaferon significantly reduced clinical and laboratory parameters of rheumatoid inflammation and significantly decreased the content of antiinflammatory cytokines in the blood. These findings attest to antiinflammatory and immunomodulating effects of these preparations. ...

journal_title：Bulletin of experimental biology and medicine

authors： Petrov VI,Babaeva AR,Solodenkova KS,Cherevkova EV,Zabolotneva YA,Kachanova MV,Sergeeva SA

更新日期：2009-09-01 00:00:00

abstract：:Secretion of chemokines under different conditions of monocyte and endothelial cell coculturing was compared. Secretion of all the studied chemokines was recorded in cocultures: IL-8/CXCL-8, MCP-1/CCL2, RANTES/CCL5, and IP-10/CXCL10. The presence of TNF-α increased the concentrations of all chemokines, the concentrati...

journal_title：Bulletin of experimental biology and medicine

authors： Starickova EA,Sokolov DI,Selkov SA,Freidlin IS

更新日期：2011-02-01 00:00:00

abstract：:The paper presents the basic criteria for glycemic control in type 2 diabetes mellitus, the data on the relationship between postprandial glycemia and the development of the late vascular complications, and methods for evaluating the glycemic index of foodstuffs and dishes in order to optimize the diets and improve th...

journal_title：Bulletin of experimental biology and medicine

authors： Sharafetdinov KhKh,Lapik IA,Vorozhko IV,Tutelyan VA

更新日期：2015-05-01 00:00:00

abstract：:We studied the effect of apolipoprotein A-I-tetrahydrocortisone complex on (14)C glucose absorption and lactate accumulation and on the rate of protein biosynthesis in isolated rat hepatocytes. The presence of apolipoprotein A-I-tetrahydrocortisone complex in the incubation medium increased absorption of labeled gluco...

journal_title：Bulletin of experimental biology and medicine

authors： Sumenkova DV,Knyazev RA,Guschya RS,Polyakov LM,Panin LE

更新日期：2009-08-01 00:00:00

abstract：:Chronic administration of neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (30 mg/kg) to C57BL/6 mice caused death of all animals within 7 days. Dipeptide analog of neurotensin active site injected with this neurotoxin protected the mice from death even after 2-week intoxication. When younger mice and lower dos...

journal_title：Bulletin of experimental biology and medicine

authors： Lutsenko VK,Vukolova MN,Kucheryanu VG,Gudasheva TA

更新日期：2003-10-01 00:00:00

abstract：:Drug resistance and viability of Mycobacterium tuberculosis were studied in 637 patients with pulmonary tuberculosis, detected by screening fluorography (group 1) and in 909 patients in whom the specific process was detected when they applied for medical care (group 2). The mycobacteria in the two groups did not diffe...

journal_title：Bulletin of experimental biology and medicine

authors： Koretskaya NM,Narkevich AN

更新日期：2014-11-01 00:00:00

abstract：:An important role in the development of the immune response is played by macrophages that acquire either anti-inflammatory M1 or anti-inflammatory M2 phenotype depending on their microenvironment. The possibility of targeted reprogramming of the initial M2 macrophage phenotype towards M1 phenotype and vice versa using...

journal_title：Bulletin of experimental biology and medicine

authors： Lyamina SV,Kruglov SV,Vedenikin TY,Borodovitsyna OA,Suvorova IA,Shimshelashvili ShL,Malyshev IY

更新日期：2012-02-01 00:00:00

abstract：:The content of urokinase- and tissue-type plasminogen activators and plasminogen activator inhibitor PAI-1 in the cytosol of primary and metastatic melanomas and benign skin pigment neoplasms was estimated by enzyme immunoassay. It was shown that local growth and invasion of melanomas are related to suppressed express...

journal_title：Bulletin of experimental biology and medicine

authors： Gershtein ES,Medvedeva SV,Babkina IV,Kushlinskii NE,Trapeznikov NN

更新日期：2001-07-01 00:00:00

abstract：:C57Bl/6 mice were intranasally infected with influenza virus A/H5N1 A/goose/Krasnoozerskoye/627/05. The mortality rate of animals reached 70% on day 14 of the disease. The lungs of animals were characterized by necroses, destruction of vessels, hemorrhagic and thrombotic complications, edematous syndrome, and early fi...

journal_title：Bulletin of experimental biology and medicine

authors： Kovner AV,Anikina AG,Potapova OV,Sharkova TV,Cherdanceva LA,Shkurupy VA,Shestopalov AM

更新日期：2012-06-01 00:00:00

abstract：:We studied the relationship between the length and tension in isolated strips of the capsules of bovine mesenteric lymph nodes. The deformation-strain and radius-pressure relationships were established in the lymph node. The capsule possesses high distensibility, modulus of elasticity at optimal tension was 0.09×10(5)...

journal_title：Bulletin of experimental biology and medicine

authors： Lobov GI,Pan'kova MN

更新日期：2011-05-01 00:00:00

abstract：:Age-related development of behavioral disorders in transgenic mice with modeled Alzheimer's disease carrying V6S3-Tg(APP695)85Dbo Tg(PSENI)85Dbo) genotype was assessed at the age of 7.5, 10 and 20 months in the following tests: open-field, plus maze, T-maze, conditioned passive avoidance response, rotarod, conflict si...

journal_title：Bulletin of experimental biology and medicine

authors： Semina II,Baichurina AZ,Makarova EA,Leushina AV,Kazakevich ZhV,Gabdrakhmanova MR,Mukhamed'yarov MA,Zefirov AL

更新日期：2015-03-01 00:00:00

abstract：:We studied the effect of constant illumination for 1 month on female GC (genetic catalepsy) and Wistar rats (control). Light exposure decreased the degree of cataleptic freezing in female GC rats (compared to the control). Norepinephrine concentration in cataleptic rats returned to normal under these conditions: this ...

journal_title：Bulletin of experimental biology and medicine

authors： Klotchkov DV,Alekhina TA,Ukolova TN,Rjazanova MA

更新日期：2008-07-01 00:00:00

abstract：:The morphology of neural and glial cells in different cerebral areas and in various experimental models was quantitatively studied by methods of computer morphometry combined with video image analysis systems. The following parameters were obtained: density of neurons and glial cells per 1 mm(2), number of satellite p...

journal_title：Bulletin of experimental biology and medicine

authors： Khudoerkov RM,Voronkov DN

更新日期：2010-07-01 00:00:00

abstract：:Human umbilical cord represents a source of multipotent stromal cells of a supreme therapeutic potential. The cells can be isolated from either fresh or cryopreserved umbilical cord tissues. DMSO is a cryoprotectant most commonly used for preservation of umbilical cord tissues; however, cyto- and genotoxicity of this ...

journal_title：Bulletin of experimental biology and medicine

authors： Arutyunyan IV,Strokova SО,Makarov АV,Mullabaeva SМ,Elchaninov АV,Lokhonina АV,Abramov АА,Fatkhudinov ТK

更新日期：2018-11-01 00:00:00

abstract：:We studied the influence of high-fat diet on the development of metabolic syndrome in rats of hypertensive ISIAH strain and normotensive WAG strain. In contrast to ISIAH rats, high-fat diet in WAG rats led visceral obesity, glucose tolerance, and dyslipidemia. DNA-binding activity of the peroxisome proliferator-activa...

journal_title：Bulletin of experimental biology and medicine

authors： Dushkin MI,Khrapova MV,Kovshik GG,Chasovskikh MI,Selyatitskaya VG,Palchikova NA

更新日期：2014-03-01 00:00:00

abstract：:The development of dissociated cells from rat embryonic spinal ganglion after transplantation to damaged nerve of adult animals was studied using immunohistochemical differentiation markers of neural and glial cells. The cell suspension obtained after dissociation of rat embryonic spinal ganglia (embryonic day 15) was...

journal_title：Bulletin of experimental biology and medicine

authors： Petrova ES,Isaeva EN,Korzhevskii DE

更新日期：2014-09-01 00:00:00

abstract：:More than 70% malignant mammary tumors contain steroid hormone receptors; this suggests the possibility of hormone therapy in the majority of patients with breast cancer (BC). The main cause of inefficiency of hormone therapy in BC is hormone resistance (tumor resistance to hormonal cytostatics). Here we discuss the m...

journal_title：Bulletin of experimental biology and medicine

authors： Scherbakov AM,Krasil'nikov MA,Kushlinskii NE

更新日期：2013-07-01 00:00:00

abstract：:The study examined effectiveness of pharmaco-cold cardioplegia employing solutions of enhanced buffer capacity during surgery of obstructive hypertrophic cardiomyopathy in adult patients (N=51) operated during 2013-2018. In group 1 (N=28), the cardioplegia was performed with HTK (Custodiol) solution, whereas in group ...

journal_title：Bulletin of experimental biology and medicine

authors： Bokeria LA,Egorov DN,Popov AE,Bledzhyants GA,Artyukhina TV,Movsesyan RR

更新日期：2020-07-01 00:00:00

abstract：:The gene expression profiles of MDA-MB-231 cell line of breast cancer and xenografts derived from this tumor in murine model were analyzed using GeneChip Human Transcriptome array 2.0 platform (Affymetrix). A more than 1000-fold increase in the MIR1973 gene expression was observed in the xenografts compared to the ori...

journal_title：Bulletin of experimental biology and medicine

authors： Fomicheva KA,Knyazev EN,Mal'tseva DV

更新日期：2017-09-01 00:00:00

abstract：:We studied the effect of adrenal cortex hormone dehydroepiandrosterone sulfate on maturation and functional activity of interferon-alpha-induced dendritic cells. Dehydroepiandrosterone sulfate stimulated differentiation and maturation of interferon-alpha-induced dendritic cell, which manifested in a decrease in the nu...

journal_title：Bulletin of experimental biology and medicine

authors： Leplina OY,Tikhonova MA,Sakchno LV,Tyrinova TV,Ostanin AA,Chernykh ER

更新日期：2009-07-01 00:00:00

abstract：:New methods of restriction fragment length polymorphism analysis were developed to distinguish polymorphic variants C190T, G191A, G857A, and 859Del of the NAT2 gene located close to each other. ...

journal_title：Bulletin of experimental biology and medicine

authors： Nikishina MV,Vavilin VA,Lyakhovich VV

更新日期：2008-10-01 00:00:00