Abstract:
:Activities of antioxidant enzymes, vitamin E level, lactate dehydrogenase isoenzyme spectrum, and effects of melatonin on these parameters were studied in the myocardium of rats aged 6, 12, 18, and 24 months exposed to different illumination regimens. The greatest number of changes was recorded in rats exposed to permanent illumination and light deprivation. Activity of SOD decreased with age, while catalase activity increased. Melatonin treatment did not modify activities of antioxidant enzymes and negligibly modified the level of tocopherol and isoenzyme spectrum of lactate dehydrogenase in rat heart.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Khizhkin EA,Ilukha VA,Ilyina TN,Unzhakov AR,Vinogradova IA,Anisimov VNdoi
10.1007/s10517-010-0945-9subject
Has Abstractpub_date
2010-09-01 00:00:00pages
354-8issue
3eissn
0007-4888issn
1573-8221journal_volume
149pub_type
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