Using the matrix-assisted laser desorption ionization for the analysis of flavonoid glycosides in objects of plant origin.

abstract：:Characteristics of distribution of cholinergic and adrenoceptor structures along the sinoatrial node artery in rat heart were evaluated by autoradiography on semithin sections by determining the density of (3)H-dihydroalprenolol and (3)H-quinuclidinyl benzilate binding sites. The relative density of binding sites for ...

journal_title：Bulletin of experimental biology and medicine

authors： Sutyagin PV,Kalinina EE,Pylaev AS

更新日期：2005-07-01 00:00:00

abstract：:We compared analgesic activities of individual alkaloids extracted from Baikal aconite (Aconitum baikalensis): napelline, hypaconitine, songorine, mesaconitine, 12-epinapelline N-oxide. The detected analgesic activity was comparable to that of sodium metamizole. The mechanisms of analgesia were different in diterpene ...

journal_title：Bulletin of experimental biology and medicine

authors： Nesterova YV,Povet'yeva TN,Suslov NI,Zyuz'kov GN,Pushkarskii SV,Aksinenko SG,Schultz EE,Kravtsova SS,Krapivin AV

更新日期：2014-08-01 00:00:00

abstract：:Study of the early embryogenesis process based on the previously suggested scheme of epithelial cambial cell work has shown that cambial (or stem) cells originate from the primary ectoderm and intensely express RhoA protein and slightly express Src kinase. This explains their stem properties and the absence of differe...

journal_title：Bulletin of experimental biology and medicine

authors： Yavisheva TM,Shcherbakov SD

更新日期：2012-05-01 00:00:00

abstract：:The second author's name should read A. Yu. Romanov. ...

journal_title：Bulletin of experimental biology and medicine

authors： Makarova NP,Romanov AY,Dolgushina NV,Parker MM,Krasnyi AM

更新日期：2018-06-01 00:00:00

abstract：:We performed a comparative study of the localization, distribution, metabolic activity, and surface properties of human bone marrow mesenchymal stromal cells after static and perfusion seeding to macroporous alginate cryogels. A simple perfusion system for mesenchymal stromal cell seeding to macroporous alginate cryog...

journal_title：Bulletin of experimental biology and medicine

authors： Petrenko YA,Ivanov RV,Lozinsky VI,Petrenko AY

更新日期：2011-02-01 00:00:00

abstract：:Studies of the molecular mechanisms of esophageal cancer development have to be carried out on sufficient amount of tumor material, obtained under conditions of controlled exposure to carcinogenic factors. Esophageal cancer models on laboratory animals serve an indispensable source of this material. One of these model...

journal_title：Bulletin of experimental biology and medicine

authors： Shubin AV,Lesovaya EA,Kirsanov KI,Antoshina EE,Trukhanova LS,Gorkova TG,Belitsky GA,Yakubovskaya MG,Demidyuk IV

更新日期：2018-03-01 00:00:00

abstract：:Loading of neutrophils with immune complexes changed their functional activity and intracellular pH. These changes depended on the size of immune complexes. UV irradiation of neutrophils loaded with immune complexes led to a molecular weight-dependent decrease in intracellular pH. After irradiation the chemiluminescen...

journal_title：Bulletin of experimental biology and medicine

authors： Konstantinova NA,Khomyakova NF

更新日期：2001-09-01 00:00:00

abstract：:A reproducible model of fetal liver regeneration was created. Resection of 20% liver was carried out in rat fetuses on day 17 of prenatal development. The organ weight was restored after 2 days at the expense of an increase in hepatocyte mitotic activity; cell hypertrophy was minor. After recovery, the cell compositio...

journal_title：Bulletin of experimental biology and medicine

authors： Elchaninov AV,Bolshakova GB

更新日期：2011-01-01 00:00:00

abstract：:We studied the effect of zoledronic acid encapsulated into liposomes (L-ZOL) on tumorassociated macrophages in the stroma of hepatocellular carcinoma xenograft. Liposomes were prepared from 1,2-dipalmitoyl-sn-glycero-3-phosphocholine, 1,2-dipalmitoyl-snglycero-3-phospho-sn-1-glycerol, and 1,2-distearoyl-sn-glycero-3-p...

journal_title：Bulletin of experimental biology and medicine

authors： Wu S,Lin X,Cui X

更新日期：2020-11-01 00:00:00

abstract：:Comparative study of cultured human bone marrow and adipose tissue (lipoaspirate) mesenchymal stem cells was carried out. The main morphological parameters, proliferative activity, expression of surface and intracellular markers of these cells were characterized. Flow cytofluorometry and histological staining showed t...

journal_title：Bulletin of experimental biology and medicine

authors： Romanov YA,Darevskaya AN,Merzlikina NV,Buravkova LB

更新日期：2005-07-01 00:00:00

abstract：:Biopsy specimens from large bronchi of patients with central and peripheral pulmonary cancer were studied. Central cancer was associated with hyperplasia and dysplasia of the epithelium, hyperplasia of glandular compartment, and pronounced immunocompetent cell response. Peripheral cancer was characterized by predomina...

journal_title：Bulletin of experimental biology and medicine

authors： Nepomnyashchikh GI,Levitskii VA,Dolgovykh AK,Naumova LA

更新日期：2002-08-01 00:00:00

abstract：:Changes in the diurnal light cycle affect the morphofunctional state of the pineal gland. The volume of the nucleus, Golgi apparatus, and mitochondria in pinealocytes decreases after 45-day exposure to bright light. After 90 days, the degree of nuclear polymorphism increased, the specific volume of the Golgi apparatus...

journal_title：Bulletin of experimental biology and medicine

authors： Gerasimov AV,Logvinov SV,Kostyuchenko VP

更新日期：2010-12-01 00:00:00

abstract：:We analyzed association of potentially regulatory polymorphisms (rs590352, rs11542583, rs3829202, rs207258, and rs4796672) with breast cancer. A significant association was found between this disease and rs2072580T>A (p=0.001) located in the overlapping promoter regions of the SART3 and ISCU genes. In women with AA an...

journal_title：Bulletin of experimental biology and medicine

authors： Degtyareva AO,Leberfarb EY,Efimova EG,Brusentsov II,Usova AV,Lushnikova EL,Merkulova TI

更新日期：2020-05-01 00:00:00

abstract：:We studied the effects of potentiated antibodies to morphine and mu-opioid receptors on animal behavior in the forced swimming test and reaction of light avoidance after morphine withdrawal. Antibodies to morphine normalized behavioral characteristics in the forced swimming test, while antibodies to mu-opioid receptor...

journal_title：Bulletin of experimental biology and medicine

authors： Pavlov IF,Epstein OI,Shtark MB

更新日期：2003-01-01 00:00:00

abstract：:Peculiarities of skin extension under vacuum applicators (nozzles) of various design was studied in 20 volunteers aged 18-25 years. The data obtained made it possible to chose optimal parameters of elastic membranes of the vacuum cups that produce stretch sufficient for vacuum-membrane skeletal muscle extension with m...

journal_title：Bulletin of experimental biology and medicine

authors： Alekseev YN,Smirnov BM,Alekseev NY

更新日期：2002-02-01 00:00:00

abstract：:The effect of low dose dichlorodiphenyltrichloroethane (DDT), omnipresent ecotoxicant and endocrine disruptor, on the functioning of the endocrine system is an urgent problem. We studied the effect of low dose DDT on thyroid status in rats. Rats receiving DDT in a dose of 1.890±0.086 μg/kg for 6 weeks showed increased...

journal_title：Bulletin of experimental biology and medicine

authors： Yaglova NV,Yaglov VV

更新日期：2014-04-01 00:00:00

abstract：:Laser radiation of different power had various effects on the properties of erythrocytes. An increase in the radiation power from 2.2 to 25 mW/cm2 was accompanied by a decrease in the erythrocyte sedimentation rate and an increase in erythrocyte filtration index. Radiation of 50 mW/cm2 induced abnormal erythrocyte agg...

journal_title：Bulletin of experimental biology and medicine

authors： Lin'kova NS,Gorshkova OP,Shuvaeva VN,Dvoretskii DP

更新日期：2008-01-01 00:00:00

abstract：:We studied the effect of allopregnanolone on stress-induced anxiety caused by intranasal administration of corticoliberin to male Wistar rats. Active and passive rats were selected by their T-maze behavior and then were tested in elevated plus maze for initial anxiety level. Basing on test results, the animals were di...

journal_title：Bulletin of experimental biology and medicine

authors： Semenova OG,Rakitskaya VV

更新日期：2014-04-01 00:00:00

abstract：:We studied the effects and mechanisms of action of NaHS, an H2S donor, on isolated phenylephrine-precontracted bovine mesenteric lymph nodes. NaHS induced concentration-dependent relaxation of lymph nodes. Removal of the endothelium reduced, but did not abolish the relaxing effect of NaHS. The relaxing effect was redu...

journal_title：Bulletin of experimental biology and medicine

authors： Lobov GI

更新日期：2020-06-01 00:00:00

abstract：:We studied in vitro cytostatic effect of doxorubicin on bone marrow cells preincubated with NAD and reduced glutathione. The presence of NAD and glutathione in the medium potentiated membrane toxicity of this antibiotic, but prevented its toxic effects on intracellular pool of pyridine nucleotides during oxidative str...

journal_title：Bulletin of experimental biology and medicine

authors： Egorova AB,Uspenskaya YA,Nefedov VP

更新日期：2001-07-01 00:00:00

abstract：:Using the experimental model of post-traumatic stress disorder (stress-restress paradigm), we studied the dynamics of activity of the hypothalamic-pituitary-adrenal system (HPAS) in adult male rats, whose mothers were daily subjected to restraint stress on days 15-19 of pregnancy. Prenatally stressed males that were s...

journal_title：Bulletin of experimental biology and medicine

authors： Pivina SG,Rakitskaya VV,Akulova VK,Ordyan NE

更新日期：2016-03-01 00:00:00

abstract：:Effects of prenatal hyperhomocysteinemia on hypothalamic regulation of estrous cycles were studied in female rats. In mature rats exposed to prenatal hyperhomocysteinemia, changes in the catecholamine content in hypothalamic areas responsible for the formation of the preovulatory surge of gonadotropin-releasing hormon...

journal_title：Bulletin of experimental biology and medicine

authors： Arutyunyan AV,Zaloznyaya IV,Kerkeshko GO,Milyutina YP,Korenevskii AV

更新日期：2017-04-01 00:00:00

abstract：:In biopsy specimens of the gastric and duodenal mucosa from patients with psoriasis we revealed severe degenerative and dystrophic changes in cells of the surface and glandular epithelium with destruction of functionally important cytoplasmic organelles. The stroma of the gastric mucosa was characterized by hyperplasi...

journal_title：Bulletin of experimental biology and medicine

authors： Khardikova SA,Nepomnyashchikh GI,Aidagulova SV,Lapii GA

更新日期：2002-11-01 00:00:00

abstract：:We studied the involvement of protein kinase Mζ (PKMζ) in the mechanisms of amnesia development within 10 days after disruption of conditioned food aversion memory with ZIP (a PKMζ inhibitor). Repeated training performed in 3 days after amnesia induction with ZIP, led to the formation of conditioned food aversion memo...

journal_title：Bulletin of experimental biology and medicine

authors： Nikitin VP,Solntseva SV,Kozyrev SA

更新日期：2019-10-01 00:00:00

abstract：:Our findings indicate that expression of matrix metalloproteinase-2 is an important prognostic marker of invasive potential of pancreatic tumors. Expression of this marker in neuroendocrine tumors (particularly in gastrinomas) can be used as a differential diagnostic criterion characterizing more malignant phenotype o...

journal_title：Bulletin of experimental biology and medicine

authors： Gurevich LE

更新日期：2003-11-01 00:00:00

abstract：:We studied the effects of neurotensin dipeptide analog Dilept (N-caproyl-L-prolyl-L-tyrosine methyl ester) on dopamine metabolism and synthesis in the nucleus accumbens of Wistar rats. Dilept increased the levels of dopamine and its metabolites (homovanillic acid and dioxyphenylalanine) and stimulated dopamine turnove...

journal_title：Bulletin of experimental biology and medicine

authors： Shubenina EV,Kudrin VS,Klodt PM,Narkevich VB,Kuznetsova EA,Gudasheva TA,Ostrovskaya RU

更新日期：2012-09-01 00:00:00

abstract：:Number and size of aggregated lymphoid nodules in the small intestine of mice exposed to radiation using a γ-irradiation unit GOBO-60 with 137Cs source were measured using the methods of visual microscopy and morphometry. Morphological status of the nodules was estimated on days 4, 28, 60, and 90 after the exposure. S...

journal_title：Bulletin of experimental biology and medicine

authors： Klochkova SV,Kvaratskheliya AG,Alekseeva NT,Nikityuk DB

更新日期：2017-12-01 00:00:00

abstract：:We studied the effects of dipeptidyl peptidase 4 (DPP4) inhibitor linagliptin on the expression of apoptosis regulator proteins Bcl-2 and Bad in the liver of db/db mice with genetically determined obesity and type 2 diabetes mellitus. The mice received daily linagliptin or saline (placebo) by gavage from week 10 to we...

journal_title：Bulletin of experimental biology and medicine

authors： Michurina SV,Cherepanova MA,Ishchenko IY,Arkhipov SA,Klimontov VV,Zav'yalov EL

更新日期：2019-06-01 00:00:00

abstract：:The effects of unilateral cortical spreading depression on the resistance to acute hypoxia with hypercapnia were studied in male SHR mice. The life-span of mice with active right hemisphere was significantly longer than that of intact, but not of sham-operated (active control) animals. Mice with active left hemisphere...

journal_title：Bulletin of experimental biology and medicine

authors： Marysheva VV,Mikheev VV,Shabanov PD

更新日期：2011-07-01 00:00:00

abstract：:We compared the efficiency of different stereoisomers of organic magnesium salts (Mg DL-, Mg D-, and Mg L-aspartate and Mg L- and Mg DL-glutamate) after oral administration under conditions of furosemide-induced magnesium deficiency. The time to complete compensation of erythrocyte magnesium level was 5 days for Mg L-...

journal_title：Bulletin of experimental biology and medicine

authors： Spasov AA,Ozerov AA,Iezhitsa IN,Kharitonova MV,Kravchenko MS,Zheltova AA

更新日期：2011-07-01 00:00:00