Abstract：
:The effects of unilateral cortical spreading depression on the resistance to acute hypoxia with hypercapnia were studied in male SHR mice. The life-span of mice with active right hemisphere was significantly longer than that of intact, but not of sham-operated (active control) animals. Mice with active left hemisphere differed significantly from intact and active control animals. It seems that the right hemisphere supports the optimal level of resistance to hypoxia with hypercapnia, while the left hemisphere performs the "antihypoxic" function. Additional analysis found no differences between the hemispheres in mice with low hypoxic resistance. The differences between the hemispheres increased with increasing the resistance to hypoxia.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Marysheva VV,Mikheev VV,Shabanov PDdoi
10.1007/s10517-011-1313-0subject
Has Abstractpub_date
2011-07-01 00:00:00pages
297-300issue
3eissn
0007-4888issn
1573-8221journal_volume
151pub_type
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