Abstract:
:The spatial and the amplitude-temporal parameters of cardiac body surface potentials were examined in female Wistar rats with experimental pulmonary hypertension during ventricular depolarization. The cardiac body surface potentials have been led from 64 subcutaneous electrodes evenly distributed across the chest surface prior to and 4 weeks after subcutaneous injection of a single dose of monocrotaline (60 mg/kg). Right ventricular hypertrophy and electrophysiological remodeling of the heart developed in rats with experimental pulmonary hypertension in 4 weeks after monocrotaline injection; these changes led to a significant increase in amplitude and temporal characteristics of the cardioelectric field on the body surface in comparison with the initial state.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Suslonova OV,Smirnova SL,Roshchevskaya IMdoi
10.1007/s10517-016-3531-ysubject
Has Abstractpub_date
2016-11-01 00:00:00pages
7-10issue
1eissn
0007-4888issn
1573-8221pii
10.1007/s10517-016-3531-yjournal_volume
162pub_type
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