Effect of calcium antagonists on ultrastructure of myocardial microvessels during open heart surgery under conditions of pharmacological and cold cardioplegia.

abstract：:We studied the structure of rhythms of BP, HR (by telemetric monitoring), electrolyte excretion (by capillary electrophoresis), and products of epiphyseal melatonin (by the urinary concentration of 6-sulfatoxymelatonin measured by ELISA) in normotensive Wistar-Kyoto rats and spontaneously hypertensive SHR rats maintai...

journal_title：Bulletin of experimental biology and medicine

authors： Blagonravov ML,Bryk AA,Medvedeva EV,Goryachev VA,Chibisov SM,Kurlaeva AO,Agafonov ED

更新日期：2019-11-01 00:00:00

abstract：:Heart rate variability was examined in random-bred albino rats at rest. The rats were clusterized according to activity of autonomic contour of heart rate control. Combination of factor and cluster analyses enhanced informative value of spectrum parameters of the heart rate variability in nonlinear rats grouped by ini...

journal_title：Bulletin of experimental biology and medicine

authors： Kur'yanova EV,Teplyi DL,Savin VF

更新日期：2009-01-01 00:00:00

abstract：:We performed immunohistochemical analysis of the expression of TGFβ, galectin-1, vimentin, and thrombospondin in the mucosa in gastric cancer of diffuse and intestinal type associated with systemic undifferentiated connective tissue dysplasia. In diffuse gastric cancer, both with and without association with connectiv...

journal_title：Bulletin of experimental biology and medicine

authors： Naumova LA,Osipova ON,Klinnikova MG

更新日期：2019-04-01 00:00:00

abstract：:We studied the effect of hepatitis C virus coinfection on T cell subpopulations in HIV-infected patients receiving antiretroviral therapy. Coinfection with hepatitis C virus was followed by a decrease in the number of naive CD4(+) T cells and an increase in the count of central CD8(+) memory T cells in these patients....

journal_title：Bulletin of experimental biology and medicine

authors： Korolevskaya LB,Shmagel KV,Saidakova EV,Shmagel NG,Slobodchikova SV,Chereshnev VA

更新日期：2016-06-01 00:00:00

abstract：:We studied the specific features of ultrasonic vocalization of Wistar rats in various motivational and emotional states. No significant changes were found in ultrasonic vocalization of rats during experimental food motivation and after the satisfaction of food requirements. The state of thirst and satisfaction of wate...

journal_title：Bulletin of experimental biology and medicine

authors： Pertsov SS,Koplik EV,Karkishchenko NN,Sudakov KV

更新日期：2012-10-01 00:00:00

abstract：:The mechanisms underlying cardioprotective activity of compound ALM-802 were studied in experiments on rats with chronic post-infarction heart failure. Real-time PCR showed that compound ALM-802 (daily intraperitoneal injections in a dose of 2 mg/kg for 28 days starting from day 91 after myocardial infarction modeling...

journal_title：Bulletin of experimental biology and medicine

authors： Kozhevnikova LM,Barchukov VV,Semenova NP,Vititnova MB,Kryzhanovskii SA

更新日期：2021-01-01 00:00:00

abstract：:The C-terminal fragment Pro-Gly-Pro of semax does not modulate the development of symptoms of neurological deficiency and mortality in rats with incomplete global cerebral ischemia. Hence, previously revealed neuroprotective effects of semax are mainly determined by corticotropin ACTH4-7 fragment. ...

journal_title：Bulletin of experimental biology and medicine

authors： Fadyukova OE,Kadi A,Bai O,Andzhusheva GM,Koshelev VB

更新日期：2005-04-01 00:00:00

abstract：:We studied the course and outcome of pregnancy in the model of inflammation of internal genital organs in female rats. It was shown that inflammation of internal genital organs impairing the state of the lymphatic region of the uterus and adnexa and relationship between the drainage and detoxification function therein...

journal_title：Bulletin of experimental biology and medicine

authors： Dergacheva TI,Borodin YI,Konenkov VI

更新日期：2014-10-01 00:00:00

abstract：:We studied the effect of Ladasten (30 mg/kg intraperitoneally for 5 days) on the subpopulation composition of T cells in immunocompetent organs of male C57Bl/6 mice during modeling of an anxious-depressive state (chronic zoosocial stress). Stress exposure of animals for 30 days was followed by a decrease in the relati...

journal_title：Bulletin of experimental biology and medicine

authors： Tallerova AV,Kovalenko LP,Kuznetsova OS,Durnev AD,Seredenin SB

更新日期：2014-01-01 00:00:00

abstract：:No appreciable disorders of cellular immunity were detected in patients with glandular cystic endometrial hyperplasia. Atypical endometrial hyperplasia was associated with quantitative changes in T lymphocytes and their subpopulations, decreased level of lymphocytes carrying activation antigens, and increased count of...

journal_title：Bulletin of experimental biology and medicine

authors： Lysenko ON,Strizhova NV,Kholodova ZhL

更新日期：2003-01-01 00:00:00

abstract：:We studied the effects of selective delta-opiate receptor agonists and antagonists on the phosphoinositide pathway in lymphocytes from healthy donors and patients with diabetes mellitus. The test compounds probably play a role in changes in the sensitivity to pharmacological substances binding to delta-opiate receptor...

journal_title：Bulletin of experimental biology and medicine

authors： Agadjanov MI,Vartanian GS,Tadevosyan YV,Batikyan TB,Agadjanova EM

更新日期：2004-02-01 00:00:00

abstract：:Modification of apolipoprotein B-100 conformation on the surface of LDL isolated from human blood was demonstrated by enzyme immunoassay with a panel of monoclonal antibodies to this protein. The study by the light transmission fluctuation method showed that incubation of LDL with phospholipases A2 or C led to associa...

journal_title：Bulletin of experimental biology and medicine

authors： Aksenov DV,Mel'nichenko AA,Suprun IV,Yanushevskaya EV,Vlasik TN,Sobenin IA,Panasenko OM,Orekhov AN

更新日期：2005-10-01 00:00:00

abstract：:Afala (ultralow-dose antibodies to prostate-specific antigen) injected for 60 days to rats with hormone-induced prostatitis caused by sulpiride prevented the development of prostatic hyperplasia and reduced the severity of histological changes. The effect of Afala was superior to that of the reference drug (Serenoa re...

journal_title：Bulletin of experimental biology and medicine

authors： Savelieva KV,Borovskaya TG,Kheyfets IA,Dugina JL,Sergeeva SA,Epstein OI

更新日期：2007-11-01 00:00:00

abstract：:Dihydroquercetin (flavonoid of plant origin) immobilized with an amino acid in lecithin nanoparticles promotes reduction of inflammatory reactions in the wound after thermal burn. The use of a liposomal complex in burn injury stabilizes endogenous antioxidant system and limits the secondary necrotic zone in the wounds...

journal_title：Bulletin of experimental biology and medicine

authors： Naumov AA,Shatalin YV,Potselueva MM

更新日期：2010-07-01 00:00:00

abstract：:We present a method of minimally invasive transcutaneous insertion of screws using a prefabricated extracorporeal navigation system using additive technologies (based on primary data obtained from the DICOM package in multi-detector computed tomography of the affected spine segment) according to the principle of perso...

journal_title：Bulletin of experimental biology and medicine

authors： Dotsenko IA,Kotomtsev VV,Medvinsky ID,Chertkov AK,Saveliev AV

更新日期：2020-04-01 00:00:00

abstract：:A test system developed by the authors was used to measure serum concentrations of soluble Fas in patients with malignant and benign tumors of different location and morphology. Relationships between soluble Fas levels and the main clinical and morphological characteristics of cancer were evaluated. It is proven that ...

journal_title：Bulletin of experimental biology and medicine

authors： Abbasova SG,Vysotskii MM,Ovchinnikova LK,Obusheva MN,Digaeva MA,Britvin TA,Bahoeva KA,Karabekova ZK,Kazantzeva IA,Mamedov UR,Manuchin IB,Davidov MI

更新日期：2009-10-01 00:00:00

abstract：:The interaction between recombinant soluble CD4 receptor (rsCD4) with human apolipoprotein A-I was studied by enzyme-linked immunosorbent assay. Our findings suggest that HIV-1 and human apolipoprotein A-I compete for the CD4 receptor and receptor for apoA-I. ...

journal_title：Bulletin of experimental biology and medicine

authors： Panin LE,Kostina NE

更新日期：2002-04-01 00:00:00

abstract：:Experimental simulation of burn was followed by accumulation of LPO products and suppression of antioxidant enzyme activity in the burn wound. Application of a synthetic analogue of indolicidin led to an increase in MDA and acylhydroperoxide concentrations in the burn wound on experimental day 1. Further application o...

journal_title：Bulletin of experimental biology and medicine

authors： Lazarenko VA,Lyashev YD,Shevchenko NI

更新日期：2014-08-01 00:00:00

abstract：:Leukocyte count decreased, relative content of neutrophils and monocytes increased, and their phagocytic activity was suppressed in rats with 1-methyl-4-phenyl-1,2,3,4-tetrahydropyridine-induced depressive syndrome at the stage of acute behavioral depression. The severity of behavioral depression inversely correlated ...

journal_title：Bulletin of experimental biology and medicine

authors： Krupina NA,Davydova TV,Fomina VG,Kryzhanovskii GN,Orlova IN

更新日期：2000-11-01 00:00:00

abstract：:Changes in the muscular tissue after subcutaneous injection of autologous bone marrow multipotent mesenchymal stromal cells transfected with GFP gene and additionally stained with cell membrane dye Vybrant CM-Dil in the projection of ligated femoral vein were studied by light microscopy with luminescence. Stromal cell...

journal_title：Bulletin of experimental biology and medicine

authors： Maiborodin IV,Morozov VV,Anikeev AA,Maslov RV,Figurenko NF,Matveeva VA,Maiborodina VI

更新日期：2018-03-01 00:00:00

abstract：:We studied the effects of chronic administration of granulocyte colony-stimulating factor in nonmobilizing doses to mice. Over 18 months of the study, 55% animals of the treatment group died of unknown cause, blood diseases and tumors were found in 20% mice, and in 5% animals pathological changes were absent. Control ...

journal_title：Bulletin of experimental biology and medicine

authors： Nifontova IN,Svinareva DA,Chertkov IL,Drize NI,Savchenko VG

更新日期：2008-05-01 00:00:00

abstract：:We studied the effect of bone marrow Thy 1,2+ cells on the growth of erythroid colonies and the role of monoamine in the regulation of proliferation and differentiation of erythroid precursor cells in experimental neuroses. Under conditions of conflict situation Thy 1,2+ cells stimulated the growth of erythropoietic p...

journal_title：Bulletin of experimental biology and medicine

authors： Skurikhin EG,Provalova NV,Pershina OV,Minakova MY

更新日期：2005-11-01 00:00:00

abstract：:The cells isolated from biopsy specimen of a patient with alcoholic liver cirrhosis and cultured under standard conditions for obtaining stromal cell culture clearly diverged during early passages into two morphologically and phenotypically different subtypes: epithelial and mesenchymal. Mesenchymal cells expressed CD...

journal_title：Bulletin of experimental biology and medicine

authors： Kholodenko IV,Kholodenko RV,Manukyan GV,Burunova VV,Yarygin KN

更新日期：2016-11-01 00:00:00

abstract：:The effects of glucocorticoids on monocyte morphology and function in vitro and the results of high-dose budesonide therapy in patients with non-severe bronchial asthma were analyzed. Before therapy with inhalation glucocorticosteroid (budesonide) characteristics of blood monocytes and the effects of different concent...

journal_title：Bulletin of experimental biology and medicine

authors： Terpigorev SA,Il'chenko VA,Vasilenko IA,Slinchenko OI,Stotskaya TV,Markina TR,Paleev NR

更新日期：2003-06-01 00:00:00

abstract：:Systemic administration of ACTH to rats with normal hormone production induced a rapid (started 3 min postinjection) and long-term (persisted 30 min) elevation of pain threshold. Complete inhibition of glucocorticoid production shortened the duration of ACTH-induced analgesia to 15 min. The biphasic effect of ACTH on ...

journal_title：Bulletin of experimental biology and medicine

authors： Bogdanov AI,Yarushkina NI

更新日期：2001-03-01 00:00:00

abstract：:We studied the effect of Herceptin therapy on the population composition of lymphocytes and percentage of CD4+CD25+ cells (regulatory T cells) in breast cancer patients. Herceptin treatment decreased the number of "professional" T suppressors (CD4+CD25+ cells and regulatory T cells) in the peripheral blood. ...

journal_title：Bulletin of experimental biology and medicine

authors： Slavina EG,Chertkova AI,Zabotina TN,Gan'shina IP,Lichinitser MR

更新日期：2006-03-01 00:00:00

abstract：:The content of low-molecular-weight components in blood serum was studied by tandem mass-spectrometry in pregnant women. Serum metabolic profiles of patients with a grave obstetrical history were detected. The most significant changes were observed for the concentrations of low-molecular-weight substances involved in ...

journal_title：Bulletin of experimental biology and medicine

authors： Khaustova SA,Senyavina NV,Tonevitsky AG,Eremina OV,Pavlovich SV

更新日期：2013-11-01 00:00:00

abstract：:We studied the influence of high-fat diet on the development of metabolic syndrome in rats of hypertensive ISIAH strain and normotensive WAG strain. In contrast to ISIAH rats, high-fat diet in WAG rats led visceral obesity, glucose tolerance, and dyslipidemia. DNA-binding activity of the peroxisome proliferator-activa...

journal_title：Bulletin of experimental biology and medicine

authors： Dushkin MI,Khrapova MV,Kovshik GG,Chasovskikh MI,Selyatitskaya VG,Palchikova NA

更新日期：2014-03-01 00:00:00

abstract：:Comparative analysis of the state of the thymus, activity of cell component of the immune system, and open field behavior of Wistar and OXYS rats showed early involution of the thymus in OXYS rats. By morphological picture this involution corresponded to accidental involution and was paralleled by low level of delayed...

journal_title：Bulletin of experimental biology and medicine

authors： Markova EV,Obukhova LA,Kolosova NG

更新日期：2003-12-01 00:00:00

abstract：:Structural characteristics of the visual cortex area 17 were studied by computer morphometry on autopsied specimens of the brain from children with perinatal injury to the central nervous system and in a group of control children without symptoms of brain injury. In children with perinatal pathology, the thickness of ...

journal_title：Bulletin of experimental biology and medicine

authors： Sal'kov VN,Khudoerkov RM

更新日期：2007-06-01 00:00:00