Changes in neuronal pulse activity of bulbar cardiovascular center after administration of dynorphin A1-13.

abstract：:Laser radiation of different power had various effects on the properties of erythrocytes. An increase in the radiation power from 2.2 to 25 mW/cm2 was accompanied by a decrease in the erythrocyte sedimentation rate and an increase in erythrocyte filtration index. Radiation of 50 mW/cm2 induced abnormal erythrocyte agg...

journal_title：Bulletin of experimental biology and medicine

authors： Lin'kova NS,Gorshkova OP,Shuvaeva VN,Dvoretskii DP

更新日期：2008-01-01 00:00:00

abstract：:Castration had no effect on baseline BP and vascular sensitivity to acetylcholine and deficiency of nitric oxide and prostacyclin in normotensive specimens. Castration of hypertensive specimens decreased BP and potentiated the hypotensive effects of acetylcholine, but did not modulate vascular sensitivity to the block...

journal_title：Bulletin of experimental biology and medicine

authors： Semyachkina-Glushkovskaya OV,Anishchenko TG,Kuznetsova AS,Kuznetsova YV,Bibikova OA,Sjestnova AA

更新日期：2012-06-01 00:00:00

abstract：:We compared cytotoxic activity of blood mononuclear leukocytes from healthy donors and lymphokine-activated killer cells generated from them towards tumor and normal cells. Lymphokine-activated killer cells exhibited higher (in comparison with blood mononuclear leukocytes) killer activity towards tumor cells. Lymphoki...

journal_title：Bulletin of experimental biology and medicine

authors： Zhukova OS,Lebedinskaya OV,Shubina IZh,Gerasimova GK,Karamzin AM,Kiselevskii MV

更新日期：2007-01-01 00:00:00

abstract：:The effects of LPS from E. coli on DNA-binding activities of PPARα and PPARγ in the liver and immune system parameters of were studied in hypertensive ISIAH rats and normotensive WAG rats. In ISIAH rats characterized by low basal level of PPARα, PPARγ, and HDL, the response of the peripheral immune system compartment ...

journal_title：Bulletin of experimental biology and medicine

authors： Shurligina AV,Dushkin MI,Melnikova EV,Panteleeva NG,Tenditnik MV,Chrapova MV,Trufakin VA

更新日期：2013-08-01 00:00:00

abstract：:Forty patients with severe asthenia were subjected to clinical, neurological, psychometric, and neurophysiologic examination before and after Enerion therapy. Psychoneurophysiological assessment with cognitive evoked potentials P300 and psychometric tests revealed serious impairment of cognitive functions in patients ...

journal_title：Bulletin of experimental biology and medicine

authors： Gordeev SA,Fedotova AV,Vein AM

更新日期：2003-11-01 00:00:00

abstract：:Pharmacokinetics of GVS-111, a new acylprolyldipeptide with nootropic properties and its penetration across the blood-brain barrier were studied in rats using HPLC. It was found that the dipeptide is absorbed in the gastrointestinal tract, enters the circulation, and penetrates through the blood-brain barrier in an un...

journal_title：Bulletin of experimental biology and medicine

authors： Boiko SS,Ostrovskaya RU,Zherdev VP,Korotkov SA,Gudasheva TA,Voronina TA,Seredenin SB

更新日期：2000-04-01 00:00:00

abstract：:One-month therapy with trimetazidine sharply decreased the content of free radical oxidation products, lipid peroxides and malonic dialdehyde, in atherogenic low-density lipoproteins in patients with coronary heart disease. Activity of glutathione peroxidase utilizing lipid peroxides in the plasma markedly increased d...

journal_title：Bulletin of experimental biology and medicine

authors： Tikhaze AK,Lankin VZ,Zharova EA,Kolycheva SV

更新日期：2000-10-01 00:00:00

abstract：:Delayed consequences of acute hypoxia were studied in 60-day-old rat pups. The animals were exposed to acute hypobaric hypoxia on day 10 of embryogenesis. The offspring of intact females served as the control. Reactivity of mesenteric lymphatic vessels to norepinephrine was studied by vital microscopy. The frequency a...

journal_title：Bulletin of experimental biology and medicine

authors： Sanzhieva LTs,Graf AS,Maslova MV,Lelekova TV,Sokolova NA

更新日期：2004-07-01 00:00:00

abstract：:Leprosy was modeled in an experiment on BALB/c, BALB/cNude, CBA, and C57BL/6ТNF-/- mice using three Mycobacterium leprae strains obtained from patients with a diagnosis of A30 according to ICD-10 from different regions of the Russian Federation. Proliferation of M. leprae of the used strains showed a temporal-quantita...

journal_title：Bulletin of experimental biology and medicine

authors： Karamova AE,Semenova VG,Verbenko DA,Obraztsova OA,Vanchugova KM,Nikonorov AA,Deryabin DG,Solomka VS,Kubanov AA

更新日期：2020-10-01 00:00:00

abstract：:Experiments on rats showed that neurospecific protein preparations reduce the severity of neurological deficit, restore the structure of individual behavior of the animals with different hypoxia tolerance, and exert antioxidant action during chronic ischemic damage to the brain unfolding during the early and late phas...

journal_title：Bulletin of experimental biology and medicine

authors： Zarubina IV,Shabanov PD

更新日期：2016-02-01 00:00:00

abstract：:Ultralow doses of antibodies to histamine in produced an antiproliferative effect on experimental animals with inflammation. Analgesic activity of antibodies to histamine was revealed on the model of acetic acid-induced writhing. ...

journal_title：Bulletin of experimental biology and medicine

authors： Krylova SG,Razina TG,Zueva EP,Amosova EN,Shilova NV,Dugina YL,Epstein OI

更新日期：2003-01-01 00:00:00

abstract：:The cells isolated from biopsy specimen of a patient with alcoholic liver cirrhosis and cultured under standard conditions for obtaining stromal cell culture clearly diverged during early passages into two morphologically and phenotypically different subtypes: epithelial and mesenchymal. Mesenchymal cells expressed CD...

journal_title：Bulletin of experimental biology and medicine

authors： Kholodenko IV,Kholodenko RV,Manukyan GV,Burunova VV,Yarygin KN

更新日期：2016-11-01 00:00:00

abstract：:Formation of Ala-Glu-Asp-Gly peptide complex with duplex DNA [poly(dA-dT):poly(dA-dT)] at neutral pH and ambient temperature was studied experimentally. Peptide binding to duplex DNA was associated with hyperchromic effect indicating local separation of the double helix. Energies of paired interactions between amino a...

journal_title：Bulletin of experimental biology and medicine

authors： Khavinson VKh,Solovyov AY,Shataeva LK

更新日期：2006-04-01 00:00:00

abstract：:Total antioxidant activity of the serum in patients with liver pathology was assessed by two chemiluminescent methods based on different models of free radical oxidation: Hb-H2O2-luminol and ABAP-luminol. Comparative analysis showed a significant, but not high correlation of the results (r=0.798), which can be explain...

journal_title：Bulletin of experimental biology and medicine

authors： Titov VN,Sazhina NN

更新日期：2014-12-01 00:00:00

abstract：:We showed for the first time that prolactin stimulates the synthesis and release of immunomodulating cytokines and lymphocyte-activating factors (e.g., interleukin-1) by peritoneal macrophages. Prolactin abolished the stress-induced inhibition of proliferation of peripheral blood lymphocytes and increased cell sensiti...

journal_title：Bulletin of experimental biology and medicine

authors： Fomicheva EE,Nemirovich-Danchenko EA,Korneva EA

更新日期：2004-06-01 00:00:00

abstract：:Silicon crystal 2-5 nm nanoparticles in the form of 1-5-μ granules in water suspension were injected intraperitoneally in a single dose to male F(1)(CBA×C57Bl/6) mice or to outbred albino rats on days 1, 7, and 14 of gestation. Silicon crystal nanoparticles in doses of 5, 25, and 50 mg/kg exhibited no cytogenetic acti...

journal_title：Bulletin of experimental biology and medicine

authors： Durnev AD,Solomina AS,Daugel-Dauge NO,Zhanataev AK,Shreder ED,Nemova EP,Shreder OV,Veligura VA,Osminkina LA,Timoshenko VY,Seredenin SB

更新日期：2010-10-01 00:00:00

abstract：:The effect of melanin solutions on the skin exposed to UV irradiation (1,050 kJ/m(2)) depended on its dose and varied from photoprotection (0.005 mg/ml) to photosensitization and phototoxicity (burn, 0.1 mg/ml). These results suggest that doses of melanin preparations should be empirically selected to achieve optimum ...

journal_title：Bulletin of experimental biology and medicine

authors： Paramonov BA,Turkovskii II,Potokin IL,Chebotarev VY

更新日期：2002-04-01 00:00:00

abstract：:We propose a new surgical approach to the treatment of familial colorectal adenomatous polyposis implying preservation of a portion of the rectum with removed mucosa. For reconstruction of the rectum, allotransplantation of the mixed culture of fetal allogenic somatic cells of the intestinal epithelium and mesenchymal...

journal_title：Bulletin of experimental biology and medicine

authors： Kogan EA,Vyshegorodtsev DV,Faizullina NM,Demura TA,Kuz'minov AM,Shelygin YA,Sukhikh GT

更新日期：2014-09-01 00:00:00

abstract：:Elimination of platelets from guinea pig splenocyte suspension (lacking megakaryocytes) with EDTA considerable reduces the efficiency cloning of splenic stromal precursor cells. It means that platelet-derived growth factors are necessary for stromal precursor cells from different organs (bone marrow, thymus, and splee...

journal_title：Bulletin of experimental biology and medicine

authors： Gorskaya YF,Shuklina EY,Nesterenko VG

更新日期：2002-03-01 00:00:00

abstract：:Infection of surfagon (gonadotropin-releasing hormone analog) in a dose of 0.1 microg/kg to male CBA mice stimulated lymphocyte migration from splenic B zones, caused moderate thinning of the thymic cortex, thickening of the zona fasciculata of the adrenal cortex with signs of corticocyte activation. After administrat...

journal_title：Bulletin of experimental biology and medicine

authors： Bobyntsev II,Dolzhikov AA,Severyanova LA

更新日期：2005-01-01 00:00:00

abstract：:Biopsy specimens from large bronchi of patients with central and peripheral pulmonary cancer were studied. Central cancer was associated with hyperplasia and dysplasia of the epithelium, hyperplasia of glandular compartment, and pronounced immunocompetent cell response. Peripheral cancer was characterized by predomina...

journal_title：Bulletin of experimental biology and medicine

authors： Nepomnyashchikh GI,Levitskii VA,Dolgovykh AK,Naumova LA

更新日期：2002-08-01 00:00:00

abstract：:Trekrezan in a dose of 25 mg/kg normalized the lymphocyte immune status and produced an energy-stabilizing effect, which manifested in decreased levels of lactate, ADP, and AMP and increased content of pyruvate and ATP in blood lymphocytes and lung tissue of rats with experimental acute bronchopneumonia. ...

journal_title：Bulletin of experimental biology and medicine

authors： Zarubina IV,Bolekhan AV,Shabanov PD

更新日期：2006-08-01 00:00:00

abstract：:We studied in vitro cytostatic effect of doxorubicin on bone marrow cells preincubated with NAD and reduced glutathione. The presence of NAD and glutathione in the medium potentiated membrane toxicity of this antibiotic, but prevented its toxic effects on intracellular pool of pyridine nucleotides during oxidative str...

journal_title：Bulletin of experimental biology and medicine

authors： Egorova AB,Uspenskaya YA,Nefedov VP

更新日期：2001-07-01 00:00:00

abstract：:The expression of Aβ42, and τ-protein, and p16 and p53 proteins was analyzed in the buccal epithelium of elderly and senile patients with Alzheimer's disease. We revealed enhanced synthesis of Alzheimer's disease markers Aβ42 (by 15-30 times) and τ-protein (by 5 times) in comparison with the corresponding values in pe...

journal_title：Bulletin of experimental biology and medicine

authors： Zuev VA,Dyatlova AS,Lin'kova NS,Kvetnaya TV

更新日期：2019-03-01 00:00:00

abstract：:Human umbilical cord represents a source of multipotent stromal cells of a supreme therapeutic potential. The cells can be isolated from either fresh or cryopreserved umbilical cord tissues. DMSO is a cryoprotectant most commonly used for preservation of umbilical cord tissues; however, cyto- and genotoxicity of this ...

journal_title：Bulletin of experimental biology and medicine

authors： Arutyunyan IV,Strokova SО,Makarov АV,Mullabaeva SМ,Elchaninov АV,Lokhonina АV,Abramov АА,Fatkhudinov ТK

更新日期：2018-11-01 00:00:00

abstract：:In mature rats, electrical stimulation of the retrotrapezoid nucleus increased the amplitude and frequency of the high-frequency peak in the firing spectrum of the phrenic nerve, while the amplitude of medium-frequency peak and the amplitude ratio of medium- to high-frequency peaks decreased. These changes in spectral...

journal_title：Bulletin of experimental biology and medicine

authors： Tatarnikov VS

更新日期：2004-08-01 00:00:00

abstract：:The type and magnitude of changes in blood flow in the anterior (cranial) and posterior (caudal) caval veins and shifts in the mean right atrial pressure induced by catecholamines (epinephrine and norepinephrine) were studied in acute experiments on cats. It was found that irrespective of right atrial pressure shifts,...

journal_title：Bulletin of experimental biology and medicine

authors： Tkachenko BI,Evlakhov VI,Poyasov IZ

更新日期：2002-11-01 00:00:00

abstract：:We studied the effect of simvastatin (24 mg/kg per os for 30 days) on DNA synthesis ((3)H-thymidine autoradiography) and free radical oxidation (chemiluminescent method) in the gastric mucosa of albino mice under normal conditions and in ulcerative process induced by single indometacin administration. Simvastatin trea...

journal_title：Bulletin of experimental biology and medicine

authors： Timoshin SS,Bragina VV,Lebedko OA,Sazonova EN,Zhivotova EY,Fleischman MY

更新日期：2012-01-01 00:00:00

abstract：:The antidepressant, psychostimulant, and nootropic effects of a composition of major and trace elements including KCl, RbNO3, magnesium sulfate, and zinc sulfate were studied on the models of behavioural despair (Porsolt test) and conditioned passive avoidance test. The preparation was found to shorten the immobilizat...

journal_title：Bulletin of experimental biology and medicine

authors： Afanasieva OG,Suslov NI,Shilova IV

更新日期：2013-06-01 00:00:00

abstract：:We compared the level of transforming growth factor-β1 (TGF-β1) in the tear fluid of 20 patients with high myopia who underwent transepithelial photorefractive keratectomy (T-PRK) in one eye and laser subepithelial keratomileusis (LASEK) in the contralateral eye. Tear fluid samples were collected with scaled microcapi...

journal_title：Bulletin of experimental biology and medicine

authors： Chen JJ,Yang YF,Zeng Y

更新日期：2020-11-01 00:00:00