Abstract:
:Infection of surfagon (gonadotropin-releasing hormone analog) in a dose of 0.1 microg/kg to male CBA mice stimulated lymphocyte migration from splenic B zones, caused moderate thinning of the thymic cortex, thickening of the zona fasciculata of the adrenal cortex with signs of corticocyte activation. After administration of 5 microg/kg surfagon we observed alteration of the splenic T zone, drastic thinning of the thymic cortex, and extension of the zona glomeruloza in the adrenal cortex. These effects were retained after castration, which attests to their steroid-independent nature.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Bobyntsev II,Dolzhikov AA,Severyanova LAdoi
10.1007/s10517-005-0225-2subject
Has Abstractpub_date
2005-01-01 00:00:00pages
101-4issue
1eissn
0007-4888issn
1573-8221pii
doijournal_volume
139pub_type
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