Myogenesis in hemopoietic tissue mesenchymal stem cell culture.

Abstract:

:The myogenic differentiation capacity of prenatal mesenchymal stem cells from the main sites of hemopoiesis (bone marrow, thymus, liver, and spleen) was studied. Myogenesis was observed in all studied cell cultures except splenic mesenchymal stem cells. Differentiating cells from the thymus, bone marrow, and liver were positively stained for skeletal muscle markers (myogenin and MyoD). Autonomously contracting structures positively stained for cardiotroponin I and slow muscle myosin, were detected in the same cultures. Our experiments revealed differences in differentiation of mesenchymal stem cells from hemopoietic organs depending on the source of cells.

journal_name

Bull Exp Biol Med

authors

Gornostaeva SN,Rzhaninova AA,Gol'dstein DV

doi

10.1007/s10517-006-0208-y

subject

Has Abstract

pub_date

2006-04-01 00:00:00

pages

493-9

issue

4

eissn

0007-4888

issn

1573-8221

journal_volume

141

pub_type

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