Effect of irradiation on colony-forming ability of stem cells from patients with ovarian cancer.

abstract：:The relationships between open field behavior, initial nociceptive thresholds, and immunoreactivity assessed according to the development of hyperthermia triggered by LPS pyrogenal were examined in Wistar rats. Behaviorally active animals demonstrated higher nociceptive thresholds and greater immunoreactivity in compa...

journal_title：Bulletin of experimental biology and medicine

authors： Abramova AY,Abramov YB

更新日期：2011-12-01 00:00:00

abstract：:Tropomyosin (Tpm) is one of the main regulatory proteins in the myocardium. In some heart pathologies, interchain disulfide crosslinking in the Tpm molecule occurs. In the ventricle, this change in the structural properties of the Tpm molecule affects calcium regulation of the actin-myosin interaction. Using an in vit...

journal_title：Bulletin of experimental biology and medicine

authors： Shchepkin DV,Matyushenko AM,Bershitsky SY,Kopylova GV

更新日期：2019-05-01 00:00:00

abstract：:We studied erythropoiesis in newborn infants delivered by mothers with normal pregnancy and gestosis. The effects of placental extracts on hemopoiesis in JCR mice were also evaluated. Our results suggest that the placenta is involved in the regulation of fetal erythropoiesis. The placenta activates fetal erythropoiesi...

journal_title：Bulletin of experimental biology and medicine

authors： Evseenko DA,Tsirel'nikov NI

更新日期：2001-11-01 00:00:00

abstract：:We studied the possibility of modification of hematotropic effects of granulocytic CSF and hyaluronidase. It was found that hyaluronidase in a dose of 20 U/mouse potentiates the specific effect of granulocytic CSF on granulocytopoiesis, while granulocytic CSF potentiates the stimulating effect of the enzyme on the ery...

journal_title：Bulletin of experimental biology and medicine

authors： Goldberg ED,Dygai AM,Zyuz'kov GN,Zhdanov VV

更新日期：2008-06-01 00:00:00

abstract：:The significance of neurospecific proteins in the diagnosis of neurotoxicity in patients with breast, lung, testicular, and ovarian cancer treated by taxane and cisplatin drugs was evaluated. The most pronounced increase in the content of these proteins and titers of autoantibodies to these proteins was observed in pa...

journal_title：Bulletin of experimental biology and medicine

authors： Lyubimova NV,Toms MG,Shakirova IN,Gurina OI,Kushlinskii NE

更新日期：2001-11-01 00:00:00

abstract：:Experiments on rats showed that neurospecific protein preparations reduce the severity of neurological deficit, restore the structure of individual behavior of the animals with different hypoxia tolerance, and exert antioxidant action during chronic ischemic damage to the brain unfolding during the early and late phas...

journal_title：Bulletin of experimental biology and medicine

authors： Zarubina IV,Shabanov PD

更新日期：2016-02-01 00:00:00

abstract：:The possibility of using hyaluronidase for the regulation of the state of different pools of mesenchymal precursors in vivo was demonstrated. The reaction of mesenchymal precursor cells depended on the dose of the enzyme. Administration of hyaluronidase in a dose of 20 U/mouse increased the content of stromal precurso...

journal_title：Bulletin of experimental biology and medicine

authors： Goldberg ED,Dygai AM,Zyuz'kov GN,Zhdanov VV,Simanina EV,Gur'yantseva LA

更新日期：2007-04-01 00:00:00

abstract：:We studied etiologic structure of bacterial intestinal infections in monkeys of Adler nursery. A total of 533 monkeys with diarrhea syndrome and monkeys dead from intestinal infections, as well as clinically healthy monkeys and animals dead from other pathologies were examined by bacteriological and molecular-genetic ...

journal_title：Bulletin of experimental biology and medicine

authors： Ardasheliya SN,Kalashnikova VA,Dzhikidze EK

更新日期：2011-10-01 00:00:00

abstract：:The stimulatory effect of a local focus of granulation tissue, created in the bone marrow cavity, on reparative osteogenesis after tibial bone fracture was detected in experimental rats by microscopic examination of histological sections, scanning electron microscopy, and X-ray electron probe microanalysis. ...

journal_title：Bulletin of experimental biology and medicine

authors： Ir'yanov YM,Dyuryagina OV

更新日期：2014-05-01 00:00:00

abstract：:The effect of panavir on Parkinson's syndrome induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine was studied in C57Bl/6 mice and outbred albino rats. Two injections of panavir significantly reduced the severity of oligokinesia and autonomic manifestations of experimentally induced Parkinson's syndrome. ...

journal_title：Bulletin of experimental biology and medicine

authors： Kalinina TS,Nerobkova LN,Voronina TA,Stovbun SV,Litvin AA,Sergienko VI

更新日期：2005-07-01 00:00:00

abstract：:We studied the mechanisms of induction of recombinase activity in peripheral T cells of patients with autoimmune type 1 diabetes mellitus. It was shown that the presence of CD40 on T cell membrane (not typical of these cells) is crucial for this process: expression of recombinase RAG-1 in diabetic patients was detecte...

journal_title：Bulletin of experimental biology and medicine

authors： Kuklina EM,Gorbunova OL,Smirnova EN

更新日期：2012-01-01 00:00:00

abstract：:Melatonin administered to intact animals increased glutathione concentration and activities of glutathione peroxidase, glutathione reductase, NADP-isocitrate dehydrogenase, and glucose-6-phosphate dehydrogenase in the liver. In animals with toxic hepatitis melatonin treatment decreased glutathione concentration and en...

journal_title：Bulletin of experimental biology and medicine

authors： Pashkov AN,Popov SS,Semenikhina AV,Rakhmanova TI

更新日期：2005-05-01 00:00:00

abstract：:No appreciable disorders of cellular immunity were detected in patients with glandular cystic endometrial hyperplasia. Atypical endometrial hyperplasia was associated with quantitative changes in T lymphocytes and their subpopulations, decreased level of lymphocytes carrying activation antigens, and increased count of...

journal_title：Bulletin of experimental biology and medicine

authors： Lysenko ON,Strizhova NV,Kholodova ZhL

更新日期：2003-01-01 00:00:00

abstract：:Activation of lysosomal proteolysis and increased coenzyme Q10 level were revealed in the liver and brain of rats with individual typological features under conditions of food deprivation. Changes in cathepsin B activity in these tissues were different in behaviorally active and passive animals. We observed indirect m...

journal_title：Bulletin of experimental biology and medicine

authors： Kirbaeva NV,Sharanova NE,Zhminchenko VM,Vasil'ev AV

更新日期：2018-07-01 00:00:00

abstract：:The content of phospholipids in various tissues was studied during synergistic interaction between two branches of the autonomic nervous system. We found higher myocardial content of choline-containing phospholipids and lower rigidity of erythrocyte membranes in rabbits with pronounced sympathetic potentiation of the ...

journal_title：Bulletin of experimental biology and medicine

authors： Lychkova AE,Smirnov VM

更新日期：2002-04-01 00:00:00

abstract：:cDNA encoding VEGF and Ig-like extracellular domains 2-4 of VEGFR-1 (sFlt-1(2-4)) were cloned into prokaryotic expression vectors pET32a and pQE60. Recombinant proteins were purified (metal affinity chromatography) and renatured. Chemiluminescent study for the interaction of recombinant VEGF and sFlt-1(2-4) showed tha...

journal_title：Bulletin of experimental biology and medicine

authors： Leopol'd AV,Baklaushev VP,Korchagina AA,Shein SA,Grinenko NF,Pavlov KA,Ryabukhin IA,Chekhonin VP

更新日期：2012-04-01 00:00:00

abstract：:Location of cathepsin D and elastase in rat uterus was studied by electron-histochemical method. Activities of both proteinases in the myometrium was detected in lysosomes of smooth-muscle cells, macrophages, and fibroblasts. ...

journal_title：Bulletin of experimental biology and medicine

authors： Ryvnyak VV,Gudumak VS,Dulgieru OF

更新日期：2003-08-01 00:00:00

abstract：:The author name M. V. Edeeva should read M. V. Edeleva. ...

journal_title：Bulletin of experimental biology and medicine

authors： Popova NA,Sysoeva GM,Nikolin VP,Kaledin VI,Tretyakov EV,Edeleva MV,Balakhnin SM,Lushnikova EL,Audran G,Mark S

更新日期：2018-05-01 00:00:00

abstract：:Manifestations of hunger and satiation in myoelectric activity patterns in different portions of the stomach were studied in chronic experiments. The state of hunger manifested in the structure of temporal organization of slow electric activity of muscles in the stomach body and antrum in the form of bimodal distribut...

journal_title：Bulletin of experimental biology and medicine

authors： Kromin AA,Zenina OY

更新日期：2012-11-01 00:00:00

abstract：:In the myocardium and skeletal muscles of rats deprived of food for 2 days, basal activity of adenylate cyclase decreased, while the sensitivity of adenylate cyclase signaling system to the stimulating effects of non-hormonal agents (guanine nucleotides and NaF) and beta-agonist isoproterinol modulating adenylate cycl...

journal_title：Bulletin of experimental biology and medicine

authors： Shpakov AO,Kuznetsova LA,Plesneva SA,Pertseva MN

更新日期：2007-07-01 00:00:00

abstract：:The level of expression of CD11b and HLA-DR surface molecules on monocyte-like THP-1 cells increased significantly as a result of transmigration of these cells through a monolayer of endothelial cells. The expression of all studied markers (CD11b, HLA-DR, and CD-14) increased significantly after transendothelial migra...

journal_title：Bulletin of experimental biology and medicine

authors： Starikova EA,Sokolov DI,Chernova AA,Freidlin IS

更新日期：2008-11-01 00:00:00

abstract：:Intraleukocytic microbicidal activity of blood neutrophilic granulocytes in cows increased with increasing the term of pregnancy, decreased over the first 2 days after labor, and increased again in the follow-up period. Activity of microbicidal systems markedly decreased after labor, especially in the winter-spring pe...

journal_title：Bulletin of experimental biology and medicine

authors： Gugushvili NN

更新日期：2003-09-01 00:00:00

abstract：:Differences in the gene expression profiles in resident macrophages (in particular, Kupffer cells) and monocytes were revealed. However, these differences in gene expression profiles do not allow considering resident liver macrophages as purely M2 macrophages and monocytes as purely M1 macrophages. At the same time, a...

journal_title：Bulletin of experimental biology and medicine

authors： Nikitina MP,Elchaninov AV,Lokhonina AV,Makarov AV,Tagirova MK,Grinberg MV,Bolshakova GB,Glinkina VV,Goldshtein DV,Fatkhudinov TK

更新日期：2020-02-01 00:00:00

abstract：:Effect of afobazole on the threshold of electrical fibrillation of the heart was studied on anesthetized rats with intact myocardium. It was shown that the drug considerably increased the threshold of electrical fibrillation of the heart, being not inferior to reference class I antiarrhythmic drugs (lidocaine and proc...

journal_title：Bulletin of experimental biology and medicine

authors： Kryzhanovskyi SA,Stolyaruck VN,Vititnova MB,Tsorin IB,Seredenin SB

更新日期：2010-09-01 00:00:00

abstract：:Studies of the molecular mechanisms of esophageal cancer development have to be carried out on sufficient amount of tumor material, obtained under conditions of controlled exposure to carcinogenic factors. Esophageal cancer models on laboratory animals serve an indispensable source of this material. One of these model...

journal_title：Bulletin of experimental biology and medicine

authors： Shubin AV,Lesovaya EA,Kirsanov KI,Antoshina EE,Trukhanova LS,Gorkova TG,Belitsky GA,Yakubovskaya MG,Demidyuk IV

更新日期：2018-03-01 00:00:00

abstract：:The kinetics of thrombin inhibition by irons ions was studied in the thrombin time test with normal plasma. The kinetic and concentration characteristics for recovery of thrombin activity by desferal were evaluated at various periods of thrombin incubation with iron ions. The thrombin time test showed that incubation ...

journal_title：Bulletin of experimental biology and medicine

authors： Azizova OA,Shvachko AG,Aseichev AV

更新日期：2009-11-01 00:00:00

abstract：:Oxidative kidney injury was compared in newborn and adult rats under conditions of ischemia/reperfusion and in experimental model of systemic inflammation induced by endotoxin (LPS of bacterial cell wall) administration. Oxidative stress in the kidney accompanied both experimental models, but despite similar oxidative...

journal_title：Bulletin of experimental biology and medicine

authors： Pevzner IB,Pavlenko TA,Popkov VA,Andrianova NV,Zorova LD,Brezgunova AA,Zorov SD,Yankauskas SS,Silachev DN,Zorov DB,Plotnikov EY

更新日期：2018-06-01 00:00:00

abstract：:We studied the interaction of the oculomotor, cervical, and vestibular systems using a specially developed technique. A series of two tests were performed on 26 healthy subjects and 42 patients with stages I-II Parkinson's disease receiving and not receiving treatment. In coordinated tests, all amplitude-time characte...

journal_title：Bulletin of experimental biology and medicine

authors： Shvetsov AY,Ivanova EA,Chigalejchik LA,Baziyan BKh

更新日期：2011-11-01 00:00:00

abstract：:Hemopoietic islets, associations of stromal (macrophages, fibroblasts) and blood (including stem) cells, are structural and functional units of the bone marrow. We studied cellular and molecular processes developing following short-term (1 h) contact of hemopoietic islets with ferromagnetic nanoparticles in a multicel...

journal_title：Bulletin of experimental biology and medicine

authors： Novitsky VA,Khlusov IA,Ryazantseva NV,Chechina OE,Feduschak TA,Ermakov AE,Uimin MA

更新日期：2011-08-01 00:00:00

abstract：:We studied the impact of acute glycerol-induced renal failure on blood levels and daily urinary excretion of arginine, monomethylarginine, and asymmetric and symmetric dimethylarginine. Acute renal failure was accompanied by enhanced daily excretion of asymmetric and symmetric dimethylarginine, increased plasma level ...

journal_title：Bulletin of experimental biology and medicine

authors： Sukhovershin RA,Gilinsky MA

更新日期：2012-08-01 00:00:00