Abstract：
:The immunobiological potential of a new microorganism species isolated from permafrost specimens (PMO strain 3M) collected from the Mammoth Mountain in Yakutia was studied in laboratory mice. PMO injected intraperitoneally in doses of 2500 to 50 × 10(6) microbial bodies caused characteristic dose-dependent effects on the structure and functions of the immune system (thymus and spleen indexes, functional activity of splenic macrophages, cellular and humoral immunity). Doses of PMO stimulating functional activities of both cellular and humoral immunity were detected.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Kalenova LF,Suhovey UG,Broushkov AV,Melnikov VP,Fisher TA,Besedin IM,Novikova MA,Efimova JA,Subbotin AMdoi
10.1007/s10517-011-1289-9subject
Has Abstractpub_date
2011-06-01 00:00:00pages
201-4issue
2eissn
0007-4888issn
1573-8221journal_volume
151pub_type
杂志文章abstract：:Effect of afobazole on the threshold of electrical fibrillation of the heart was studied on anesthetized rats with intact myocardium. It was shown that the drug considerably increased the threshold of electrical fibrillation of the heart, being not inferior to reference class I antiarrhythmic drugs (lidocaine and proc...
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