Abstract:
:We studied the neuroprotective effect of a new selective anxiolytic afobazole on rats with bilateral focal ischemic stroke in the prefrontal cortex caused by photothrombosis. Intraperitoneal injection of 5 mg/kg afobazole 1 h after surgery and over the next 8 days (daily treatment) produced a neuroprotective effect. Afobazole was far superior to the reference cerebroprotective drug cavinton (4 mg/kg) by neuroprotective activity.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Seredenin SB,Romanova GA,Shakova FMdoi
10.1007/s10517-008-0051-4subject
Has Abstractpub_date
2008-02-01 00:00:00pages
207-9issue
2eissn
0007-4888issn
1573-8221journal_volume
145pub_type
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