Abstract:
:Hypochlorite produced in vivo by activated neutrophils, monocytes, and macrophages modifies blood lipoproteins and intensifies free radical lipid peroxidation, which probably plays a key role in the early stages of atherosclerotic vascular damages.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Panasenko OM,Sergienko VIdoi
10.1023/a:1017926309665subject
Has Abstractpub_date
2001-05-01 00:00:00pages
407-15issue
5eissn
0007-4888issn
1573-8221journal_volume
131pub_type
杂志文章,评审abstract::The interaction between dopamine D1 and D2 receptors plays a role in immunomodulation. The results of thus interaction depends on the degree of receptor activation with selective agonists in different doses. Combined treatment with agonists of D1 and D2 receptors in high doses had a synergistic effect in the mechanism...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-006-0218-9
更新日期:2006-05-01 00:00:00
abstract::Pro-Gly-Pro and its metabolite Gly-Pro effectively prevented the development of erosive and ulcerative lesions of the gastric mucosa in rats under conditions of water-immersion restraint stress by restoring the oxidatant-antioxidant balance in the total fraction of gastric mucosa cells. Pro-Gly was least effective in ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-010-0866-7
更新日期:2010-07-01 00:00:00
abstract::The effect of intravenous transplantation of mesenchymal stem cells on the recovery of cognitive functions was studied in Wistar-Kyoto rats after brain stroke induced by occlusion of the middle cerebral artery in the left hemisphere. Analysis 2 and 5 weeks after stroke showed that transplantation of mesenchymal stem c...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-006-0405-8
更新日期:2006-10-01 00:00:00
abstract::Over many years, tick-borne infections remain one of the most serious threats to human health worldwide. The immune response to these infections in a human after confirmed bite by an infected carrier at the early stages of infection in the absence of clinical symptoms can be the first indicator of the presence of the ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-019-04405-3
更新日期:2019-03-01 00:00:00
abstract::Local injection of 4 nmol moxonidine (unilaterally) into the rostroventrolateral medulla of spontaneously hypertensive rats (SHR-SP) decreased mean blood pressure and heart rate by 24+/-3 and 3+/-4%, respectively. Pretreatment with the I1/alpha2-receptor antagonist efaroxan abolished the moxonidine-induced decrease in...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/a:1017943901070
更新日期:2001-04-01 00:00:00
abstract::We studied the effects of stress exposure during the adolescent period of development (SAPD) on the parameters of inflammatory painful response and the level of depression-like behavior in prenatally stressed adult male rats. In addition, we analyzed the effects of selective serotonin (5-HT) reuptake inhibitor fluoxet...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-020-04875-w
更新日期:2020-07-01 00:00:00
abstract::Exposure of rats with experimental diabetes mellitus to wide-band electromagnetic radiation generated by He-Ne laser and modulated by the pancreas and spleen is informing and phenomenological method prolonging animal life span, normalizing blood glucose level, and promoting regeneration of the pancreas. ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-007-0049-3
更新日期:2007-02-01 00:00:00
abstract::Multivariate analysis was used to examine the morphology of mixed saliva crystals in 55 healthy men and the patients with suspected malignant prostate gland diseases. The established changes in the shape of dendritic crystals in the saliva from prostate-problematic patients were corroborated by the cluster and discrim...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-006-0338-2
更新日期:2006-08-01 00:00:00
abstract::We studied daily dynamics of proliferative activity of embryonic fibroblast-like cells in culture during the logarithmic growth phase. Daily increase in cell count in the culture showed a 4-day rhythm that persisted over 3 weeks of culturing. In cultures from different animals, the phase of this rhythm was synchronous...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-020-04962-y
更新日期:2020-09-01 00:00:00
abstract::We analyzed the expression of galectin-1 and galectin-3 in tumor tissue in stomach and colorectal cancer with and without tissue eosinophilia. Low expression of galectin-3 was detected in all patients with malignant gastrointestinal tumors irrespective of the presence of eosinophilia. Low expression of galectin-1 was ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-018-4142-6
更新日期:2018-06-01 00:00:00
abstract::The content of phospholipids in various tissues was studied during synergistic interaction between two branches of the autonomic nervous system. We found higher myocardial content of choline-containing phospholipids and lower rigidity of erythrocyte membranes in rabbits with pronounced sympathetic potentiation of the ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/a:1016203713719
更新日期:2002-04-01 00:00:00
abstract::Forty patients with severe asthenia were subjected to clinical, neurological, psychometric, and neurophysiologic examination before and after Enerion therapy. Psychoneurophysiological assessment with cognitive evoked potentials P300 and psychometric tests revealed serious impairment of cognitive functions in patients ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 临床试验,杂志文章
doi:10.1023/b:bebm.0000017083.58029.ca
更新日期:2003-11-01 00:00:00
abstract::Application of anxiolytic drug Selank to hippocampal slices increased the amplitude and discharge rate of spontaneous inhibitory postsynaptic currents in rat hippocampal pyramidal CA1 neurons. In some neurons, Selank-induced up-regulation of spontaneous inhibitory postsynaptic currents was preceded by a transient decr...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-017-3676-3
更新日期:2017-03-01 00:00:00
abstract::Comparative analysis of proteoglycans in the control and tumor tissue of human mammary gland revealed disorders in the biosynthesis of dermatan sulfate proteoglycans in tumor cells. Using the methods of reverse transcription-PCR and Western blotting for the analysis of decorin expression we showed that these disorders...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-007-0326-1
更新日期:2007-09-01 00:00:00
abstract::We studied the effect of allopregnanolone on stress-induced anxiety caused by intranasal administration of corticoliberin to male Wistar rats. Active and passive rats were selected by their T-maze behavior and then were tested in elevated plus maze for initial anxiety level. Basing on test results, the animals were di...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-014-2433-0
更新日期:2014-04-01 00:00:00
abstract::The effects of intranasal administration of oxytocin on the levels and metabolism of monoamines in symmetrical structures of the brain of white outbred mice kept under conditions of long-term social isolation were studied by HPLC. Disappearance of initial right-sided asymmetry in the content of dopamine metabolites in...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-017-3887-7
更新日期:2017-10-01 00:00:00
abstract::Oxidized dextran is suggested for prevention of infection induced by influenza A/H5N1 viruses, methods of its use and doses are determined. Two intravenous injections of dextran 3 and 1 days before experimental infection of outbred mice by influenza A/H5N1 A/goose/Krasnoozerskoye/627/05 virus resulted in a high preven...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-014-2704-9
更新日期:2014-11-01 00:00:00
abstract::The parameters of thermal dependence of H+ transport into human erythrocytes in the presence of furosemide were measured. The relationship between these changes and function of band 3 protein of the erythrocyte membrane is discussed. ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/b:bebm.0000046935.36523.a4
更新日期:2004-07-01 00:00:00
abstract::Brain-derived neurotrophic factor (BDNF) plays the central role in the mechanisms of regulation of neurogenesis and neuroplasticity. Impairment of these mechanisms is considered as one of the main etiological factors of depression. Dimeric dipeptide mimetic of BDNF loop 4 bis-(N-monosuccinyl-l-seryl-l-lysine) hexameth...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-017-3638-9
更新日期:2017-02-01 00:00:00
abstract::The location and activities of nitric oxide synthases in synovial cells during different stages of inflammatory process were studied by the immunocytochemical method in animals with experimental rheumatoid arthritis. Direct involvement of the NOergic mechanisms in the development of adjuvant arthritis was demonstarted...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-007-0203-y
更新日期:2007-05-01 00:00:00
abstract::Apoptosis markers (p53, PUMA, p21, and Mdm2) were studied in patients with rheumatoid arthritis at the early and late stages of disease on bone marrow smears and frozen sections of the articular synovial membrane. The target molecules were found in all patients. The early stage was characterized by maximum expression ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-014-2353-z
更新日期:2014-01-01 00:00:00
abstract::The location and level of IL-8 and TGF-beta2 expression in the fimbrial compartment of fallopian tubes and IL-10 expression in the endometrium of women with pyoinflammatory adnexal diseases were studied by in situ hybridization. These diseases are associated with considerable changes in the levels of local production ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/a:1024193216377
更新日期:2003-03-01 00:00:00
abstract::Alloxan-induced diabetes mellitus in rats was characterized by persistent increase in blood levels of corticosterone, while chronic granulomatous inflammation induced by silicon dioxide and its combination with alloxan-induced diabetes mellitus were associated with transient increase in blood corticosterone level foll...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-010-1026-9
更新日期:2010-11-01 00:00:00
abstract::Reductase activity of 17beta-hydroxysteroid oxidoreductase in biopsy specimens of prostatic cancer and benign hyperplasia, and prostatic intraepithelial neoplasia and serum concentrations of testosterone, 5alpha-dihydrotestosterone, 4-androstene-3,17-dione were compared in patients and healthy individuals. Reductase a...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-005-0387-y
更新日期:2005-06-01 00:00:00
abstract::We studied the influence of pretreatment with chemical mildronate analogue sibusol on the course of experimental gastric ulcer in rats. Sibusol produced a protective effects on the stomach and duodenum. ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/b:bebm.0000024380.24282.0b
更新日期:2004-01-01 00:00:00
abstract::Intensive exercise triggers the cascade processes of body adaptation, including modulation of splisosome functioning, and can lead to modification of its activity and choice of alternative exons. We studied the effect of exercise of the maximum aerobic power on activation of transcription of genes involved in the spli...
journal_title:Bulletin of experimental biology and medicine
pub_type: 临床试验,杂志文章
doi:10.1007/s10517-009-0593-0
更新日期:2009-06-01 00:00:00
abstract::Plasma LDL content increased in rats with mild chronic heart failure, but decreased in animals with severe pathology. The lipid profile of β-adrenoceptor antagonists depended on their selectivity. The most selective antagonists of β-adrenoceptors had little effect on the lipid composition. Nonselective β-adrenoceptor ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-013-2312-0
更新日期:2013-12-01 00:00:00
abstract::The data of genome-wide association analysis suggest that human 6p21.3 chromosomal region (localization of HLA genes) contains polymorphic loci influencing the risk of developing non-Hodgkin's lymphomas. We analyzed association of rs2647012 and rs805288 loci with the risk for non-Hodgkin's malignant lymphomas in the p...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-014-2520-2
更新日期:2014-06-01 00:00:00
abstract::Regeneratory activities of Baikal aconite alkaloids were studied on the excision skin wound model. Manifest wound healing effects of songorine, napelline, and hypaconitine were detected. The therapeutic efficiency was based on activation of residual mesenchymal progenitor elements. The development of this phenomenon w...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:
更新日期:2012-10-01 00:00:00
abstract::We studied carbohydrate specificity and isotypes of antibodies to BSA-conjugated tetrasaccharide, a repeating unit of the capsular polysaccharide of Streptococcus pneumoniae serotype 14, in mouse polyclonal sera and hybridoma-synthesized products. Natural IgM antibodies to the tetrasaccharide containing epitopes simil...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-019-04376-5
更新日期:2019-02-01 00:00:00