Abstract:
:The interaction between dopamine D1 and D2 receptors plays a role in immunomodulation. The results of thus interaction depends on the degree of receptor activation with selective agonists in different doses. Combined treatment with agonists of D1 and D2 receptors in high doses had a synergistic effect in the mechanisms of immunomodulation. Receptor agonists in low doses suppressed the immune response. Our results suggest that weak activation of one of these receptors is accompanied by inactivation of the other receptor type.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Devoino LV,Al'perina EL,Gevorgyan MM,Cheido MAdoi
10.1007/s10517-006-0218-9subject
Has Abstractpub_date
2006-05-01 00:00:00pages
553-5issue
5eissn
0007-4888issn
1573-8221journal_volume
141pub_type
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