Effects of substance S-1 on rats with impaired hearing.

abstract：:We revealed an antimetastatic effect of thymus-dependent corpuscular antigen (sheep erythrocytes) injected intravenously or intraperitoneally in sensitizing or high doses alone or in a complex with a course dose of cyclophosphamide to C57Bl/6 mice with Lewis carcinoma. Injection of the antigen appreciably reduced the ...

journal_title：Bulletin of experimental biology and medicine

authors： Mosienko MD,Mosienko VS,Solyanik GI,Kovalenko NG

更新日期：2004-06-01 00:00:00

abstract：:Human recombinant erythropoietin adsorbed on poly(butyl)cyanoacrylate nanoparticles and administered intraperitoneally in a dose of 0.05 mg/kg exhibited a neuroprotective effect in experimental intracerebral posttraumatic hematomas (hemorrhagic stroke) and reduced animal mortality. Human recombinant erythropoietin, na...

journal_title：Bulletin of experimental biology and medicine

authors： Solev IN,Balabanyan VY,Volchek IA,Elizarova OS,Litvinova SA,Garibova TL,Voronina TA

更新日期：2013-06-01 00:00:00

abstract：:Immunosorbent removing beta2-microglobulin from human blood plasma was synthesized on the basis of sheep monospecific polyclonal antibodies to beta2-microglobulin and conditions ensuring effective regeneration of the immunosorbent for its repeated use were selected. Relationships between adsorption capacity and the vo...

journal_title：Bulletin of experimental biology and medicine

authors： Shabunina IV,Afanas'eva OI,Pokrovskii SN

更新日期：2001-10-01 00:00:00

abstract：:Effects of Miramistin and Phosprenil on biofilms of S. pyogenes, S. aureus, E. coli, L. acidophilus, and L. plantarum were studied. Significant differences in the effects of these substances on mature biofilms of microorganisms and the process of their formation were observed. Miramistin had significant inhibiting eff...

journal_title：Bulletin of experimental biology and medicine

authors： Danilova TA,Danilina GA,Adzhieva AA,Minko AG,Nikolaeva TN,Zhukhovitskii VG,Pronin AV

更新日期：2017-08-01 00:00:00

abstract：:We studied the effect of audiovisual stimulation training course on physical development, functional state of the cardiovascular system, blood biochemical parameters, and hormonal status of athletes. The training course led to improvement of physical performance and adaptive capacities of the circulatory system, incre...

journal_title：Bulletin of experimental biology and medicine

authors： Golovin MS,Golovin MS,Aizman RI

更新日期：2016-09-01 00:00:00

abstract：:The effects of intranasal pretreatment with antibodies against glutamate on focal penicillin-induced epileptic activity were studied by recording electrocorticogram in non-anesthetized freely moving male Wistar rats. Anticonvulsant effects of intranasal administration of anti-glutamate antibodies (300 μg/kg) 1 h befor...

journal_title：Bulletin of experimental biology and medicine

authors： Kuznetsova LV,Karpova MN,Vetrile LA,Klishina NY

更新日期：2013-09-01 00:00:00

abstract：:Carbacholine reduced, while baclofen and norepinephrine increased resting membrane potential in earthworm somatic muscle cells. In the presence of carbacholine, neither norepinephrine, nor baclofen hyperpolarized the membrane. Ouabain decreased resting potential and abolished the effects of carbacholine, norepinephrin...

journal_title：Bulletin of experimental biology and medicine

authors： Volkov EM,Sabirova AR,Volkov ME,Zefirov AL

更新日期：2007-08-01 00:00:00

abstract：:We demonstrated the influence of short peptides on the expression of signaling molecules in organotypic culture of the pineal gland from 3-month-old rats. Peptides Ala-Glu-Asp-Gly and Lys-Glu-Asp stimulate the expression of proliferative protein Ki-67 in pineal gland culture. These peptides as well as Glu-Asp-Arg and ...

journal_title：Bulletin of experimental biology and medicine

authors： Khavinson VKh,Linkova NS,Chalisova NI,Dudkov AV,Koncevaya EA

更新日期：2011-11-01 00:00:00

abstract：:Forty patients with severe asthenia were subjected to clinical, neurological, psychometric, and neurophysiologic examination before and after Enerion therapy. Psychoneurophysiological assessment with cognitive evoked potentials P300 and psychometric tests revealed serious impairment of cognitive functions in patients ...

journal_title：Bulletin of experimental biology and medicine

authors： Gordeev SA,Fedotova AV,Vein AM

更新日期：2003-11-01 00:00:00

abstract：:We studied the reaction of the microglia of the anterior horns of the rat spinal cord to intraperitoneal administration of bacterial LPS. Immunohistochemical analysis showed that acute systemic inflammation leads to activation of more than half of microglial cells as soon as in 24 h after LPS injection, while the tota...

journal_title：Bulletin of experimental biology and medicine

authors： Kolos EA,Korzhevskii DE

更新日期：2017-08-01 00:00:00

abstract：:The cytotoxic effects of human blood serum were studied under normal and pathological conditions. The contribution of the complement system to the realization of this effect was demonstrated. Significant differences in the serum capacity to kill foreign cells were detected for healthy subjects and asthmatics. Bovine s...

journal_title：Bulletin of experimental biology and medicine

authors： Arkhipova EN,Cherepov AB,Medvedeva YS,Alchinova IB,Karganov MY

更新日期：2012-09-01 00:00:00

abstract：:We studied the phospholipid composition of high-density lipoproteins in patients with hypercholesterolemia before and after treatment with simvastatin. Individual phospholipids were separated by thin-layer chromatography on glass plates coated with silica gel. It was found that apart from hypolipidemic effect, simvast...

journal_title：Bulletin of experimental biology and medicine

authors： Ozerova IN,Paramonova IV,Olfer'ev AM,Akhmedzhanov NM,Aleksandrova MA,Perova NV

更新日期：2001-08-01 00:00:00

abstract：:Antisense oligonucleotide to alpha2A-adrenoceptors increased the levels of mRNA (reverse polymerase chain reaction) and protein for a key executioner protease of apoptosis caspase-3 (immunoblotting assay) in the cerebral cortex of newborn rats. The relationship between the observed effect and low expression of alpha2-...

journal_title：Bulletin of experimental biology and medicine

authors： Men'shanov PN,Bannova AV,Il'inykh FA,Dygalo NN

更新日期：2007-03-01 00:00:00

abstract：:We studied the dynamics of indexes for the system of endogenous regulation of NO bioavailability. The content of NO synthase inhibitors (monomethylarginine and asymmetric dimethylarginine) in the blood of mice was measured after intraperitoneal injections of a nonionic surfactant poloxamer 407 for 2 and 14 weeks. The ...

journal_title：Bulletin of experimental biology and medicine

authors： Gilinsky MA,Sukhovershin RA,Cherkanova MS

更新日期：2015-11-01 00:00:00

abstract：:We studied electrophysiological parameters and morphological changes in the adrenal glands and spleen of CBA mice feeding a low-choline diet and/or ethanol-containing diet. The polarization coefficient underwent similar changes in the adrenal glands and spleen, which was associated with different contribution of imped...

journal_title：Bulletin of experimental biology and medicine

authors： Tornuev YV,Nepomnyashchikh LM,Koldysheva EV

更新日期：2005-11-01 00:00:00

abstract：:The epileptogenic effects of applications of NMDA and kainic acid solutions to the frontal cortex were attenuated in rats receiving ketogenic diet (80% lipids, 3.3% carbohydrates, and 16.7% proteins) during 4 weeks. Spike latency increased, the power of focal epileptic activity decreased, and focus lifetime was shorte...

journal_title：Bulletin of experimental biology and medicine

authors： Kresyun VI,Polyasny VA,Godovan VV,Godlevsky LS

更新日期：2013-02-01 00:00:00

abstract：:We studied the seasonal effects of peptide preparation Selank on orientation and exploratory activity in 36 arctic ground squirrels Citellus undulatus in the open-field and hole-board tests. Selank most significantly increased behavioral activity of hibernating animals in the spring and fall. The test peptide had no e...

journal_title：Bulletin of experimental biology and medicine

authors： Semenova TP,Kozlovskaya MM,Zuikov AV,Kozlovskii II,Andreeva LA

更新日期：2005-12-01 00:00:00

abstract：:Heart rate variability was examined in random-bred albino rats at rest. The rats were clusterized according to activity of autonomic contour of heart rate control. Combination of factor and cluster analyses enhanced informative value of spectrum parameters of the heart rate variability in nonlinear rats grouped by ini...

journal_title：Bulletin of experimental biology and medicine

authors： Kur'yanova EV,Teplyi DL,Savin VF

更新日期：2009-01-01 00:00:00

abstract：:Effect of one-day and chronic (3 week) drinking of 0.1% caffeine as a single source of fluid on anxiety in rats with different anxiety level (either genetically determined or individually acquired) was studied. When housed in groups, Fisher-344 rats had a significantly higher anxiety level than WAG/G rats. When the ra...

journal_title：Bulletin of experimental biology and medicine

authors： Sudakov SK,Medvedeva OF,Rusakova IV,Figurina IB

更新日期：2001-12-01 00:00:00

abstract：:Potential created by electrogenic ionic pumps under conditions of maximum activation in a warm standard ionic medium with K(+) after preincubation in cold potassium-free solution has two components: a higher ouabaine-insensitive "stationary" component, and a lower "regulatory" component sensitive to ouabaine, furosemi...

journal_title：Bulletin of experimental biology and medicine

authors： Volkov EM,Sabirova AR,Nurullin LF,Zefirov AL

更新日期：2006-12-01 00:00:00

abstract：:We studied the effect of ozonized physiological saline on phagocytic properties of polymorphonuclear neutrophilic leukocytes from dog blood. Intravenous infusion of the examined doses of ozonized saline stimulated phagocytosis. Repeated intravenous infusion (48 h after) of the same dose was followed by a significant d...

journal_title：Bulletin of experimental biology and medicine

authors： Volkhovskaya NB,Tkachenko SB,Belopolsky AA

更新日期：2008-11-01 00:00:00

abstract：:The second author's name should read A. Yu. Romanov. ...

journal_title：Bulletin of experimental biology and medicine

authors： Makarova NP,Romanov AY,Dolgushina NV,Parker MM,Krasnyi AM

更新日期：2018-06-01 00:00:00

abstract：:Reductase activity of 17beta-hydroxysteroid oxidoreductase in biopsy specimens of prostatic cancer and benign hyperplasia, and prostatic intraepithelial neoplasia and serum concentrations of testosterone, 5alpha-dihydrotestosterone, 4-androstene-3,17-dione were compared in patients and healthy individuals. Reductase a...

journal_title：Bulletin of experimental biology and medicine

authors： Degtyar VG,Babkina TV,Kazantseva IA,Morozov AP,Trapeznikova MF,Kushlinskii NE

更新日期：2005-06-01 00:00:00

abstract：:Comparative study on inbred mouse stains showed that in vitro response of T lymphocytes from tuberculosis-susceptible I/St mice to mycobacterial antigens did not differ from that of T lymphocytes from resistant mouse strains. The defect appeared only in the presence of virulent mycobacteria and was not related to T ly...

journal_title：Bulletin of experimental biology and medicine

authors： Radaeva TV,Nikonenko BV

更新日期：2000-06-01 00:00:00

abstract：:The role of signaling molecules in synthesis of humoral regulators of granulocytopoiesis by the hematopoietic microenvironmental cells during stress was analyzed using specific inhibitors. The major role in stimulation of the synthesis of granulocytic CSF during stressful stimulation is played by PI3K/Akt signaling ca...

journal_title：Bulletin of experimental biology and medicine

authors： Zhdanov VV,Miroshnichenko LA,Udut EV,Polyakova TY,Zyuz'kov GN,Simanina EV,Sherstoboev EY,Stavrova LA,Agafonov VI,Minakova MY,Dygai AM

更新日期：2019-01-01 00:00:00

abstract：:The content of biogenic amines and their metabolism in the ancient part of the amygdala (paleoamygdala) differ in male and female rats and depended on the phase of the estrous cycle. ...

journal_title：Bulletin of experimental biology and medicine

authors： Akhmadeev AV,Kalimullina LB

更新日期：2013-10-01 00:00:00

abstract：:We present a method of minimally invasive transcutaneous insertion of screws using a prefabricated extracorporeal navigation system using additive technologies (based on primary data obtained from the DICOM package in multi-detector computed tomography of the affected spine segment) according to the principle of perso...

journal_title：Bulletin of experimental biology and medicine

authors： Dotsenko IA,Kotomtsev VV,Medvinsky ID,Chertkov AK,Saveliev AV

更新日期：2020-04-01 00:00:00

abstract：:Macrophage activity was studied after treatment with hybrid molecules obtained by condensation of terpenic acid residues (betulinic and betulonic acids) and α-tocopherol analogues (α-tocopherol hemisuccinate and Trolox acid). As distinct from betulinic acid and α-tocopherol hemisuccinate, hybrid molecules did not exhi...

journal_title：Bulletin of experimental biology and medicine

authors： Ivanova AN,Belsky YP,Spivak AY,Danilets MG,Belska NV,Chalitova RR,Ligatcheva AA,Uchasova EG

更新日期：2011-10-01 00:00:00

abstract：:The features of B16 melanoma progression in male C57BL/6 mice with initially high and low resistance to hypoxia were studied. To assess the resistance to hypoxia, the mice were placed in a low-pressure chamber at a simulated altitude of 10,000 m. One month after testing, B16 melanoma was inoculated to high- and low-re...

journal_title：Bulletin of experimental biology and medicine

authors： Fridman IA,Ponomarenko EA,Makarova OV,Postovalova EA,Zolotova NA,Khochanskiy DN,Mkhitarov VA,Tsvetkov IS,Kosyreva AM

更新日期：2020-01-01 00:00:00

abstract：:MEK, PI3, p38, tyrosine, and mTOR kinases are not involved in the regulation of heart resistance to the arrhythmogenic action of short-term ischemia/reperfusion in non-adapted rats. ...

journal_title：Bulletin of experimental biology and medicine

authors： Maslov LN,Mukhomedzyanov AV,Tsibulnikov SY,Chauski EI,Khaliulin IG,Portnichenko AG

更新日期：2015-04-01 00:00:00