Cholinergic and GABAergic innervation regulate activity of electrogenic ionic pump in earthworm somatic muscle cells.

Abstract:

:Carbacholine reduced, while baclofen and norepinephrine increased resting membrane potential in earthworm somatic muscle cells. In the presence of carbacholine, neither norepinephrine, nor baclofen hyperpolarized the membrane. Ouabain decreased resting potential and abolished the effects of carbacholine, norepinephrine, and baclofen on membrane potential. It was hypothesized that carbacholine directly inhibited the ouabain-sensitive component of Na+/K+ pump and abolished the activating effect of norepinephrine and baclofen.

journal_name

Bull Exp Biol Med

authors

Volkov EM,Sabirova AR,Volkov ME,Zefirov AL

doi

10.1007/s10517-007-0279-4

subject

Has Abstract

pub_date

2007-08-01 00:00:00

pages

163-5

issue

2

eissn

0007-4888

issn

1573-8221

journal_volume

144

pub_type

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