Abstract:
:Immunosorbent removing beta2-microglobulin from human blood plasma was synthesized on the basis of sheep monospecific polyclonal antibodies to beta2-microglobulin and conditions ensuring effective regeneration of the immunosorbent for its repeated use were selected. Relationships between adsorption capacity and the volume of immobilized ligand, antigen concentration in the solution, and duration of incubation were studied. The adsorbent can be used for effective and specific removal of beta2-microglobulin from the plasma of patients on chronic hemodialysis.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Shabunina IV,Afanas'eva OI,Pokrovskii SNdoi
10.1023/a:1013679630607subject
Has Abstractpub_date
2001-10-01 00:00:00pages
984-6issue
4eissn
0007-4888issn
1573-8221journal_volume
132pub_type
杂志文章abstract::Structural changes in the brain of outbred mice were studied after infection with influenza A/H5N1 strain isolated in the Novosibirsk region. High mortality was observed after intranasal infection. Examination of brain specimens revealed vasculopathies with thrombosis of the microcirculatory vessels, pericellular and ...
journal_title:Bulletin of experimental biology and medicine
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pub_type: 杂志文章
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journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:
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journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
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doi:10.1007/s10517-017-3754-6
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journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-009-0449-7
更新日期:2009-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s10517-019-04603-z
更新日期:2019-09-01 00:00:00