Abstract:
:We studied functional activity of neutrophilic granulocytes and monocytes isolated from the peripheral blood of women during the follicular and luteal phases of the menstrual cycle. It was shown that phagocytic activity of neutrophilic granulocytes increases, their intracellular oxygen-dependent bactericidal activity decreases, and the number of monocyte extracellular traps increases in women in the luteal phase of the menstrual cycle in comparison with the follicular phase.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Smirnova TG,Savochkina AY,Dolgushin II,Nikushkina KV,Samuseva IVdoi
10.1007/s10517-018-4318-0subject
Has Abstractpub_date
2018-12-01 00:00:00pages
222-224issue
2eissn
0007-4888issn
1573-8221pii
10.1007/s10517-018-4318-0journal_volume
166pub_type
杂志文章abstract::Model experiments on biomicroscopy of mesenteric microvessels in laboratory rats were performed to evaluate the effect of natural metabolites (e.g., amino acid glycine) on the microcirculation. The effect of glycine was determined from a change in the diameter of arterioles. Application of glycine (0.1 ml, 1 M) to the...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-009-0498-y
更新日期:2009-03-01 00:00:00
abstract::Chronic administration of neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (30 mg/kg) to C57BL/6 mice caused death of all animals within 7 days. Dipeptide analog of neurotensin active site injected with this neurotoxin protected the mice from death even after 2-week intoxication. When younger mice and lower dos...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/b:bebm.0000010949.44563.15
更新日期:2003-10-01 00:00:00
abstract::Phenibut and its derivatives normalized cellular (index of delayed-type hypersensitivity reaction) and humoral (antierythrocyte antibody titer) immunity and the lymphoproliferative processes in immunocompetent organs of animals with cyclophosphamide-induced immunosuppression. This indicates pronounced immunocorrective...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-009-0571-6
更新日期:2009-05-01 00:00:00
abstract::Oxygen-dependent processes in peripheral blood monocytes were intensified in patients with metabolic cardiovascular syndrome. This was manifested in increased production of O(2)(*-) and NO. Among metabolic factors (cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triacylglycerols...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/b:bebm.0000038145.39332.85
更新日期:2004-05-01 00:00:00
abstract::NAD, cytochrome c, and energostim modulated the fluorescence emission spectrum of trifluoperazine in the solution and in microsomal suspension. The data suggest that NAD and energostim modify structural and conformational characteristics of the dopamine receptor-trifluoperazine complex. These changes probably underlie...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/b:bebm.0000031560.92650.3d
更新日期:2004-03-01 00:00:00
abstract::We studied changes in cerebral and central hemodynamics during active orthostatic load in 26 healthy men aging 20-26 years. Two types of central hemodynamics were revealed: progressive increase in blood pressure throughout the test (type 1) or initial blood pressure increase followed by its decrease with maximum incre...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-008-0146-y
更新日期:2008-05-01 00:00:00
abstract::In patients with ovarian cancer, the colony-forming capacity and radiosensitivity of clonogenic tumor cells from the primary node and metastases (ascites) differed considerably. ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/a:1012362804949
更新日期:2001-06-01 00:00:00
abstract::Intranigral administration of glutamate to rats with parkinsonian syndrome induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine augmented the development of parkinsonian symptoms (oligokinesia and muscular rigidity), but did not affect motor activity of intact animals. Memantine administered intraperitoneally in pa...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/BF02682089
更新日期:2000-07-01 00:00:00
abstract::The study examined the effect of H2S on the tone of cerebral arteries in rats after global cerebral ischemia/reperfusion injury and cooperation between NO and H2S in the control over cerebral circulation during the postischemic period. In control sham-operated and in experimental rats with ischemia/reperfusion injury,...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-020-04759-z
更新日期:2020-03-01 00:00:00
abstract::The author name G. A. Chastikina should read G. A. Chastikin. ...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章,已发布勘误
doi:10.1007/s10517-017-3883-y
更新日期:2017-09-01 00:00:00
abstract::Alloxan-induced diabetes mellitus in rats was characterized by persistent increase in blood levels of corticosterone, while chronic granulomatous inflammation induced by silicon dioxide and its combination with alloxan-induced diabetes mellitus were associated with transient increase in blood corticosterone level foll...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-010-1026-9
更新日期:2010-11-01 00:00:00
abstract::We studied brown adipose tissue isolated from mice receiving 20% ethanol as a single source of fluid. In vitro O2 utilization by brown adipose tissue decreased after one month of forced alcohol intake, but surpassed the control after 3 months of ethanol drinking. The absolute and relative weight of brown adipose tissu...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/a:1014590710930
更新日期:2001-12-01 00:00:00
abstract::The type and magnitude of changes in blood flow in the anterior (cranial) and posterior (caudal) caval veins and shifts in the mean right atrial pressure induced by catecholamines (epinephrine and norepinephrine) were studied in acute experiments on cats. It was found that irrespective of right atrial pressure shifts,...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/a:1022617709181
更新日期:2002-11-01 00:00:00
abstract::We studied the effects of calcitonin, parathyrin, and Ca(2+) channel antagonist isoptin and agonist Bay-K-8644 on glucose consumption by muscle (diaphragm) and adipose (epididymal) tissues and insulin-stimulated glucose consumption in vivo and in vitro. Calcitonin and parathyrin did not alter glucose consumption; para...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-009-0677-x
更新日期:2009-08-01 00:00:00
abstract::The formation of an ischemic focus in the myocardium is paralleled by autoimmune processes involving immunoglobulins with abnormal thermal solubility, cryoglobulins. Serum levels of cryoglobulins and their complexes were measured in 25 patients with Q-forming myocardial infarction on days 1, 2, 3, 7, and 14 of the dis...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-011-1155-9
更新日期:2011-02-01 00:00:00
abstract::We studied the effects of individual or combination treatment with monoclonal antibodies 5F5-B6 in ultralow doses specifically marking mossy fibers in rat hippocampus and antibodies to S100 protein during long-term post-tetanic potentiation in hippocampal slices. The possible mechanisms of changes produced by therapeu...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/a:1024715821327
更新日期:2003-01-01 00:00:00
abstract::The effects of a new thietanylbenzimidazole derivative (K-134) on estrous cycles, conception processes, and sexual behavior of female rats were studied. Two-week oral treatment with K-134 in doses of 5 and 50 mg/kg shortened the estrus phase and prolonged proestrus. Changes in sexual behavior were presented by activat...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-015-3034-2
更新日期:2015-09-01 00:00:00
abstract::Serum activity of tartrate-resistant acid phosphatase 5b (TRAP 5b) in patients with breast cancer and prostate cancer having bone metastases was much higher than in healthy donors and patients without skeletal injuries. TRAP 5b activity in patients with breast cancer and multiple bone metastases surpassed that in pati...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/b:bebm.0000046945.95479.d6
更新日期:2004-07-01 00:00:00
abstract::The concentrations of the key factors of molecular pathogenesis of prehypertension (angiotensin II, HLDF24, S100b, endothelin, autoantibodies to these molecules, and VEGF) were analyzed in subjects with optimal BP (<120/80 mm Hg) and prehypertension (120-139/80-89 mm Hg). Comparative and correlation analysis of the le...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-020-04696-x
更新日期:2020-01-01 00:00:00
abstract::We studied the effect of adrenal cortex hormone dehydroepiandrosterone sulfate on maturation and functional activity of interferon-alpha-induced dendritic cells. Dehydroepiandrosterone sulfate stimulated differentiation and maturation of interferon-alpha-induced dendritic cell, which manifested in a decrease in the nu...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-009-0619-7
更新日期:2009-07-01 00:00:00
abstract::We compared the efficiency of different stereoisomers of organic magnesium salts (Mg DL-, Mg D-, and Mg L-aspartate and Mg L- and Mg DL-glutamate) after oral administration under conditions of furosemide-induced magnesium deficiency. The time to complete compensation of erythrocyte magnesium level was 5 days for Mg L-...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-011-1323-y
更新日期:2011-07-01 00:00:00
abstract::The anti-ischemic effect of synthetic and pharmacologically tested anxiolytic afobazole (10 mg/kg intravenously) was studied on anesthetized rats with acute endocardial ischemia caused by isoproterenol infusion (20 mg/kg/min). A calcium antagonist verapamil (1 mg/kg intravenously) belonging to the group of phenyl alky...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-013-2246-6
更新日期:2013-10-01 00:00:00
abstract::We studied the effect of 10-week treatment with intranasal insulin (0.5 IU/day) on glucose tolerance, glucose utilization, lipid metabolism, functions of pancreatic β cells, and insulin system in the liver of rats with cafeteria diet-induced metabolic syndrome. The therapy reduced body weight and blood levels of insul...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-017-3762-6
更新日期:2017-06-01 00:00:00
abstract::Intensive exercise triggers the cascade processes of body adaptation, including modulation of splisosome functioning, and can lead to modification of its activity and choice of alternative exons. We studied the effect of exercise of the maximum aerobic power on activation of transcription of genes involved in the spli...
journal_title:Bulletin of experimental biology and medicine
pub_type: 临床试验,杂志文章
doi:10.1007/s10517-009-0593-0
更新日期:2009-06-01 00:00:00
abstract::The rats were divided into groups demonstrating extremely high and low stress reactivity depending on the results of testing for the nociceptive threshold and thermolability in response to bacterial lipopolysaccharide administration. Specific structural features of the nucleus and mitochondria were revealed in neurons...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-007-0419-x
更新日期:2007-11-01 00:00:00
abstract::Blood levels of stem cell marker proteins CD34 and osteonectin were studied in male patients with coronary atherosclerosis by direct biomagnetic separation of proteins with magnetic microspheres using the PureProteome Protein A and Protein G Magnetic Beads proteomic technology. High concentration of osteonectin in the...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-011-1333-9
更新日期:2011-07-01 00:00:00
abstract::We studied the functional role of individual subtypes of muscarinic cholinoceptors in the pathogenesis of neuroleptic parkinsonism in rats. Blockade of M4 receptors prevented the development of extrapyramidal disorders, which was abolished by simultaneous blockade of M2 receptors. The data suggest that various subtype...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1023/b:bebm.0000038155.56296.50
更新日期:2004-05-01 00:00:00
abstract::We studied the effect of Ladasten (30 mg/kg intraperitoneally for 5 days) on the subpopulation composition of T cells in immunocompetent organs of male C57Bl/6 mice during modeling of an anxious-depressive state (chronic zoosocial stress). Stress exposure of animals for 30 days was followed by a decrease in the relati...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-014-2343-1
更新日期:2014-01-01 00:00:00
abstract::We studied the effects of phenazepam (0.075 mg/kg) after pretreatment (5 minutes before) with naloxone (10 mg/kg) on open-field behavior of C57Bl/6 and BALB/c mice. In ex vivo experiments, we studied the effects of naloxone (1 and 10 mg/kg) on receptor binding of [(3)H]-flunitrazepam by membranes of brain fraction (P1...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/s10517-013-2150-0
更新日期:2013-07-01 00:00:00
abstract::Chinese hamster cells in culture were blocked in prometaphase by the addition of chloral hydrate. After 2 h the chloral hydrate was removed and the ultrastructural changes in the kinetochore studied during recovery of mitosis. The kinetochore in the blocked cells is a disc measuring 300-350 nm in diameter and 30-35 nm...
journal_title:Bulletin of experimental biology and medicine
pub_type: 杂志文章
doi:10.1007/BF00799327
更新日期:1975-01-01 00:00:00