Pattern of changes in central and cerebral hemodynamics in the basilar artery during active orthostasis in healthy individuals.

abstract：:Elimination of platelets from guinea pig splenocyte suspension (lacking megakaryocytes) with EDTA considerable reduces the efficiency cloning of splenic stromal precursor cells. It means that platelet-derived growth factors are necessary for stromal precursor cells from different organs (bone marrow, thymus, and splee...

journal_title：Bulletin of experimental biology and medicine

authors： Gorskaya YF,Shuklina EY,Nesterenko VG

更新日期：2002-03-01 00:00:00

abstract：:We studied the effect of electroconvulsive therapy on cognitive functions in rats with depression-like disorder caused by exposure to ultrasound of varying frequency (20-45 kHz). Object recognition and Morris water-maze tests revealed no negative effects of the therapy on memory. Moreover, positive effect of therapy w...

journal_title：Bulletin of experimental biology and medicine

authors： Ushakova VM,Zubkov EA,Morozova AY,Gorlova AV,Pavlov DA,Inozemtsev AN,Chekhonin VP

更新日期：2017-09-01 00:00:00

abstract：:We studied the effects of neurotensin dipeptide analog Dilept (N-caproyl-L-prolyl-L-tyrosine methyl ester) on dopamine metabolism and synthesis in the nucleus accumbens of Wistar rats. Dilept increased the levels of dopamine and its metabolites (homovanillic acid and dioxyphenylalanine) and stimulated dopamine turnove...

journal_title：Bulletin of experimental biology and medicine

authors： Shubenina EV,Kudrin VS,Klodt PM,Narkevich VB,Kuznetsova EA,Gudasheva TA,Ostrovskaya RU

更新日期：2012-09-01 00:00:00

abstract：:Serum concentration of copper, immunoreactive polypeptides of ceruloplasmin and its oxidase activity, and the number of copper atoms per ceruloplasmin molecule were decreased in patients with Parkinson's disease in comparison with the corresponding parameters in age-matched healthy individuals, but the ratio of apocer...

journal_title：Bulletin of experimental biology and medicine

authors： Karpenko MN,Ilyicheva EY,Muruzheva ZM,Milyukhina IV,Orlov YA,Puchkova LV

更新日期：2018-03-01 00:00:00

abstract：:Effects of Miramistin and Phosprenil on biofilms of S. pyogenes, S. aureus, E. coli, L. acidophilus, and L. plantarum were studied. Significant differences in the effects of these substances on mature biofilms of microorganisms and the process of their formation were observed. Miramistin had significant inhibiting eff...

journal_title：Bulletin of experimental biology and medicine

authors： Danilova TA,Danilina GA,Adzhieva AA,Minko AG,Nikolaeva TN,Zhukhovitskii VG,Pronin AV

更新日期：2017-08-01 00:00:00

abstract：:Apoptosis of blood neutrophils from healthy donors was studied under conditions of cell culturing with different concentrations of H(2)O(2), selective NO synthase inhibitor, and inductor of NO synthesis (L-arginine). In vitro incubation of neutrophilic leukocytes with 5 mM H(2)O(2) led to activation of the apoptotic p...

journal_title：Bulletin of experimental biology and medicine

authors： Stepovaya YA,Zhavoronok TV,Starikov YV,Bychkov VA,Chasovskih NY,Starikova YG,Petina GV,Novitsky VV,Ryazantseva NV

更新日期：2008-12-01 00:00:00

abstract：:Agonists of glutamate ionotropic (NMDA) and metabotropic receptors (mGluRI and mGluRIII) had the regulatory effect on ADP-ribosyl cyclase/CD38 activity in cerebellar granular cells of newborn rats. Perinatal hypoxic-ischemic brain injury was followed by dysregulation of this mechanism. ...

journal_title：Bulletin of experimental biology and medicine

authors： Salmina AB,Okuneva OS,Mikhutkina SV,Malinovskaya NA,Morgun AV,Zykova LD,Yudin GV,Laletin DV,Fursov MA,Frolova OV,Tagaeva GA,Bolshakova EV

更新日期：2011-03-01 00:00:00

abstract：:The effect of p-tyrosol on the spontaneous level of DNA damage in the cells of the bone marrow, liver, kidney, and rectum of mice (series I) and on the genotoxic effects of cytostatic drugs with different mechanisms of action in rat testicular cells (series II) was studied by DNA comet assay on C57BL/6 mice. p-Tyrosol...

journal_title：Bulletin of experimental biology and medicine

authors： Borovskaya TG,Vychuzhanina AV,Grigor'eva VA,Kollantay OV,Goldberg VE,Dygai AM

更新日期：2020-06-01 00:00:00

abstract：:In vivo cytogenetic effects of cyclophosphamide was simultaneously evaluated in 7 mouse organs. Cyclophosphamide produced most pronounced changes in the urinary bladder and bone marrow, the main target organs for this carcinogen. Mutagenic effects of the preparation were also detected in the lungs, large intestine, an...

journal_title：Bulletin of experimental biology and medicine

authors： Sycheva LP

更新日期：2001-04-01 00:00:00

abstract：:Experiments on the model of mouse BCG-induced granulomatous showed that the content of glycosaminoglycans and proteoglycans in the extracellular matrix of the liver and lungs are changed at the early stages of inflammation (days 3 and 30 postinfection) before cell destruction in the organs begins. This is related to d...

journal_title：Bulletin of experimental biology and medicine

authors： Kim LB,Shkurupy VA,Putyatina AN

更新日期：2015-01-01 00:00:00

abstract：:Model experiments on biomicroscopy of mesenteric microvessels in laboratory rats were performed to evaluate the effect of natural metabolites (e.g., amino acid glycine) on the microcirculation. The effect of glycine was determined from a change in the diameter of arterioles. Application of glycine (0.1 ml, 1 M) to the...

journal_title：Bulletin of experimental biology and medicine

authors： Podoprigora GI,Nartsissov YR

更新日期：2009-03-01 00:00:00

abstract：:The production of blood radicals and activity of superoxide dismutase in erythrocytes increased in rats with contact burn trauma (20%). In animals with burn trauma antioxidant activity of the plasma was much lower, while myeloperoxidase content in the lung tissue and epidermis was higher than in control rats. The comp...

journal_title：Bulletin of experimental biology and medicine

authors： Mikhal'chik EV,Ivanova AV,Anurov MV,Titkova SM,Pen'kov LY,Korkina LG

更新日期：2004-09-01 00:00:00

abstract：:Hepatoprotective activity of pyrimidine derivative hydroxymethyluracil was studied on the model of acute paracetamol-induced liver damage in rats. Hydroxymethyluracil was shown to produce a strong hepatoprotective effect. ...

journal_title：Bulletin of experimental biology and medicine

authors： Mirsaev TR

更新日期：2007-05-01 00:00:00

abstract：:The content of MMP-8 and MMP-9 in oral fluid of 145 patients (95 women and 50 men, 18-52 years) was measured by enzyme immunoassay. We examined 63 subjects with the intact periodontium and 82 patients with chronic generalized periodontitis (25 patients with mild disease, 45 patients with moderate disease, and 12 patie...

journal_title：Bulletin of experimental biology and medicine

authors： Kushlinskii NE,Solovykh EA,Karaoglanova TB,Bayar U,Gershtein ES,Troshin AA,Kostyleva OI,Grinin VM,Maksimovskaya LN,Yanushevitch OO

更新日期：2011-12-01 00:00:00

abstract：:An integrative systemic model of pharmacological reaction to a phytopreparation was created as a result of conceptual structurization of facts and formalization of causal relations. The use of the new methodological approach to the choice, primary screening, and profound studies of plants for prospective addition ther...

journal_title：Bulletin of experimental biology and medicine

authors： Mitrofanova IY,Yanitskaya AV,Butenko DV

更新日期：2013-09-01 00:00:00

abstract：:Intraleukocytic microbicidal activity of blood neutrophilic granulocytes in cows increased with increasing the term of pregnancy, decreased over the first 2 days after labor, and increased again in the follow-up period. Activity of microbicidal systems markedly decreased after labor, especially in the winter-spring pe...

journal_title：Bulletin of experimental biology and medicine

authors： Gugushvili NN

更新日期：2003-09-01 00:00:00

abstract：:The dynamics of LPO marker malondialdehyde formation and peroxidase-destroying activity was studied in homogenized organs of guinea pigs, immunized with thermoextracts from S and L forms Brucella abortus I-206. The L form brucella thermoextract exhibited a lower reactogenicity and adequately activated the antioxidant ...

journal_title：Bulletin of experimental biology and medicine

authors： Dubrovina VI,Balakhonov SV,Yurieva OV,Starovoitova TP,Barannikova NL,Tokareva LE,Pyatidesyatnikova AB,Yastremskaya KY,Shkaruba TT

更新日期：2018-06-01 00:00:00

abstract：:We studied erythropoiesis in newborn infants delivered by mothers with normal pregnancy and gestosis. The effects of placental extracts on hemopoiesis in JCR mice were also evaluated. Our results suggest that the placenta is involved in the regulation of fetal erythropoiesis. The placenta activates fetal erythropoiesi...

journal_title：Bulletin of experimental biology and medicine

authors： Evseenko DA,Tsirel'nikov NI

更新日期：2001-11-01 00:00:00

abstract：:Application of anxiolytic drug Selank to hippocampal slices increased the amplitude and discharge rate of spontaneous inhibitory postsynaptic currents in rat hippocampal pyramidal CA1 neurons. In some neurons, Selank-induced up-regulation of spontaneous inhibitory postsynaptic currents was preceded by a transient decr...

journal_title：Bulletin of experimental biology and medicine

authors： Povarov IS,Kondratenko RV,Derevyagin VI,Myasoedov NF,Skrebitsky VG

更新日期：2017-03-01 00:00:00

abstract：:Experiments on rats showed that activation of the peripheral ion channel TRPM8 with menthol and rapid cooling (decrease in core temperature by 3°C) led to 1.5-fold activation of the expression of TRPV3 ion channel gene in the posterior hypothalamus, but had no effect on the expression of this gene in the anterior hypo...

journal_title：Bulletin of experimental biology and medicine

authors： Kozyreva TV,Evtushenko AA,Voronova IP,Khramova GM,Kozaruk VP

更新日期：2018-12-01 00:00:00

abstract：:The content of phospholipids in various tissues was studied during synergistic interaction between two branches of the autonomic nervous system. We found higher myocardial content of choline-containing phospholipids and lower rigidity of erythrocyte membranes in rabbits with pronounced sympathetic potentiation of the ...

journal_title：Bulletin of experimental biology and medicine

authors： Lychkova AE,Smirnov VM

更新日期：2002-04-01 00:00:00

abstract：:Functional activity of the thyroid gland is reduced in Wistar rats with acute experimental endotoxicosis developing in response to sublethal dose of LPS and paralleled by polarization of the immune response by the Th-1 type. This decrease does not depend on the level of thyrotropic hormone and correlates with the prod...

journal_title：Bulletin of experimental biology and medicine

authors： Yaglova NV

更新日期：2009-06-01 00:00:00

abstract：:Rarely repeated episodes of 1-h immobilization in rats were accompanied by an increase in the content of molecular products of lipid peroxidation and decrease in the amount of oxidatively modified proteins. Monoamine oxidase B inhibitor deprenyl prevented the poststress activation of lipid peroxidation. ...

journal_title：Bulletin of experimental biology and medicine

authors： Tseilikman VE,Sinitsky AI,Poyarkov KA,Vojdaev EV

更新日期：2009-12-01 00:00:00

abstract：:We developed wound coating based on natural biopolymer chitosan with additional components (ceruloplasmin, L-asparaginic acid, and glycerol). Experiments on albino male rats demonstrated its regeneratory, antioxidant, and antibacterial effects on wounds involving all layers of the skin. Due to chemical composition and...

journal_title：Bulletin of experimental biology and medicine

authors： Gladkova EV,Babushkina IV,Norkin IA,Mamonova IA,Puchin'yan DM,Konyuchenko EA

更新日期：2016-03-01 00:00:00

abstract：:Clinical and laboratory studies were carried out in 38 pregnant women with antiphospholipid syndrome. Increased functional activity of platelets and decreased protein-producing function of the placenta were observed starting from the early terms of gestation. These disorders were followed by the development of hyperco...

journal_title：Bulletin of experimental biology and medicine

authors： Bogdanovich RN,Chikalovets IV

更新日期：2002-10-01 00:00:00

abstract：:The concentrations of the key factors of molecular pathogenesis of prehypertension (angiotensin II, HLDF24, S100b, endothelin, autoantibodies to these molecules, and VEGF) were analyzed in subjects with optimal BP (<120/80 mm Hg) and prehypertension (120-139/80-89 mm Hg). Comparative and correlation analysis of the le...

journal_title：Bulletin of experimental biology and medicine

authors： Sherstnev VV,Gruden MA,Karlina VP,Ryzhov VM,Kuznetsova AV,Senko OV

更新日期：2020-01-01 00:00:00

abstract：:Pial arteries of different diameter were studied in intact rats and after 6-month modeling of chronic tobacco smoking in rats. Expression of tachykinin NK1 receptors in pial arteries was studied by biomicroscopy and immunohistochemical methods. Chronic tobacco smoking induced considerable reorganizations of the arteri...

journal_title：Bulletin of experimental biology and medicine

authors： Zakharchuk NV,Chertok VM,Nevzorova VA,Gonchar EY

更新日期：2017-07-01 00:00:00

abstract：:Pharmacokinetics of GVS-111, a new acylprolyldipeptide with nootropic properties and its penetration across the blood-brain barrier were studied in rats using HPLC. It was found that the dipeptide is absorbed in the gastrointestinal tract, enters the circulation, and penetrates through the blood-brain barrier in an un...

journal_title：Bulletin of experimental biology and medicine

authors： Boiko SS,Ostrovskaya RU,Zherdev VP,Korotkov SA,Gudasheva TA,Voronina TA,Seredenin SB

更新日期：2000-04-01 00:00:00

abstract：:Intensive exercise triggers the cascade processes of body adaptation, including modulation of splisosome functioning, and can lead to modification of its activity and choice of alternative exons. We studied the effect of exercise of the maximum aerobic power on activation of transcription of genes involved in the spli...

journal_title：Bulletin of experimental biology and medicine

authors： Tonevitsky EA,Trushkin EV,Shkurnikov MU,Akimov EB,Sakharov DA

更新日期：2009-06-01 00:00:00

abstract：:Intraperitoneal administration of substance S-1 to male Wistar rats with impaired hearing markedly increased hearing acuity. Substance S-1 had no negative effects on hearing in intact animals. ...

journal_title：Bulletin of experimental biology and medicine

authors： Shestakova EV

更新日期：2002-01-01 00:00:00