Abstract:
:We developed wound coating based on natural biopolymer chitosan with additional components (ceruloplasmin, L-asparaginic acid, and glycerol). Experiments on albino male rats demonstrated its regeneratory, antioxidant, and antibacterial effects on wounds involving all layers of the skin. Due to chemical composition and buffer component, the biodegraded wound coating optimizes all phases of the wound process, accelerates by 22-28% the reparative regeneration, and leads to anatomic and functional restoration of injured sites. High absorption capacity recommends its use in the treatment of wounds with profuse exudation.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Gladkova EV,Babushkina IV,Norkin IA,Mamonova IA,Puchin'yan DM,Konyuchenko EAdoi
10.1007/s10517-016-3258-9subject
Has Abstractpub_date
2016-03-01 00:00:00pages
715-7issue
5eissn
0007-4888issn
1573-8221pii
10.1007/s10517-016-3258-9journal_volume
160pub_type
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