Location and intensity of IL-8 and TGF-beta2 mRNA production in the fimbrial compartment of fallopian tubes and IL-10 in the endometrium in patients with pyoinflammatory adnexal diseases.

Abstract:

:The location and level of IL-8 and TGF-beta2 expression in the fimbrial compartment of fallopian tubes and IL-10 expression in the endometrium of women with pyoinflammatory adnexal diseases were studied by in situ hybridization. These diseases are associated with considerable changes in the levels of local production of these cytokines. Inflammatory infiltration and epithelial cells were most active producers of IL-9 and TGF-beta2 in the fimbrial compartment of fallopian tubes, while in the endometrium IL-10 gene was expressed at a high level primarily in the glandular epithelial cells.

journal_name

Bull Exp Biol Med

authors

Zhdanov AV,Kurbanova DF,Sosulina LY,Davydova MP,Ezhova LS,Sukhikh GT

doi

10.1023/a:1024193216377

subject

Has Abstract

pub_date

2003-03-01 00:00:00

pages

272-5

issue

3

eissn

0007-4888

issn

1573-8221

journal_volume

135

pub_type

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