Abstract:
:Tenoten is a new anxiolytic and antidepressant based on antibodies to brain-specific protein S-100B. Experimental studies demonstrated the effect of tenoten on mechanisms of neuronal plasticity and manifestations of higher nervous activity. Tenoten is clinically comparable with amitryptiline, sertraline, and phenazepam, but does not produce potent sedative relaxation effect typical of these drugs. The study demonstrated considerable improvement of the control over brain frontal compartment effector functions. Tenoten is recommended not only at the stage of moderate cognitive impairment, but also in manifest cerebrovascular pathologies characterized by pronounced impairment of the regulatory functions of the frontal compartments of the brain.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Duma SA,Shishkin SVdoi
10.1007/s10517-009-0679-8subject
Has Abstractpub_date
2009-08-01 00:00:00pages
353-6issue
2eissn
0007-4888issn
1573-8221journal_volume
148pub_type
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