Abstract:
:Human embryonic myogenic precursors were transplanted into muscles of mdx mice with hereditary dystrophin-deficient muscular dystrophy. Transplantation induced the synthesis of human dystrophin. The number of dystrophin-positive fibers progressively decreased, however, some of them were preserved even 5 months after transplantation. Our results indicate that xenogeneic transplantation of embryonic myogenic precursors compensates the genetic defect in dystrophin-deficient mice.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Yarygin VN,Sukhikh GT,Sitnikov VF,Stenina MA,Kuznetsov AB,Poltavtseva RA,Krivov LI,Voevodin DA,Savchuk VI,Revishchin AV,Korochkin LI,Aleksandrova MAdoi
10.1023/a:1026009517850subject
Has Abstractpub_date
2003-07-01 00:00:00pages
88-92issue
1eissn
0007-4888issn
1573-8221journal_volume
136pub_type
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