Morphological study of burn wound healing with the use of collagen-chitosan wound dressing.

Abstract:

:Experiments on the model of thermal skin burn in rats showed that the use of wound dressing based on collagen-chitosan complex Kollakhit-Bol in local treatment of grade IIIb skin burns increased healing rate by accelerating the formation of granulation and fibrous connective tissues and reducing crust thickness in comparison with Kollakhit coating. Kollakhit-Bol provided targeted stimulation of reparative processes in the treatment of grade IIIb burns by creating favorable conditions for grafting full thickness skin transplant or dermal-epidermal skin equivalent. In the topical treatment of thermal burn, Kollakhit-Bol application shortened the phases of alteration and exudation and accelerated transition to the productive phase of the inflammatory process with phagocytosis and neoangiogenesis activation.

journal_name

Bull Exp Biol Med

authors

Kirichenko AK,Bolshakov IN,Ali-Riza AE,Vlasov AA

doi

10.1007/s10517-013-2031-6

subject

Has Abstract

pub_date

2013-03-01 00:00:00

pages

692-6

issue

5

eissn

0007-4888

issn

1573-8221

journal_volume

154

pub_type

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