Morphofunctional basis for recovery of locomotor movements in rats with completely crossed spinal cord.

abstract：:We compared analgesic activities of individual alkaloids extracted from Baikal aconite (Aconitum baikalensis): napelline, hypaconitine, songorine, mesaconitine, 12-epinapelline N-oxide. The detected analgesic activity was comparable to that of sodium metamizole. The mechanisms of analgesia were different in diterpene ...

journal_title：Bulletin of experimental biology and medicine

authors： Nesterova YV,Povet'yeva TN,Suslov NI,Zyuz'kov GN,Pushkarskii SV,Aksinenko SG,Schultz EE,Kravtsova SS,Krapivin AV

更新日期：2014-08-01 00:00:00

abstract：:The author name G. A. Chastikina should read G. A. Chastikin. ...

journal_title：Bulletin of experimental biology and medicine

authors： Maiborodin IV,Morozov VV,Anikeev AA,Figurenko NF,Maslov RV,Matveeva VA,Chastikin GA,Maiborodina VI

更新日期：2017-09-01 00:00:00

abstract：:Crossbred CC57BR/Mv mice inherited tryptophan oxygenase gene and predisposition to alcohol consumption from parent BALB/c and C57BL mice, respectively. In CC57BR/Mv mice no relationships were found between alcohol consumption, tryptophan oxygenase activity, and single nucleotide substitutions in intron 6 of the TDO2 g...

journal_title：Bulletin of experimental biology and medicine

authors： Kaledin VI,Klimova NV,Vasil'ev GV,Ivanova EA,Vasil'eva ED,Il'nitskaya SI

更新日期：2003-10-01 00:00:00

abstract：:Comparative study of cultured human bone marrow and adipose tissue (lipoaspirate) mesenchymal stem cells was carried out. The main morphological parameters, proliferative activity, expression of surface and intracellular markers of these cells were characterized. Flow cytofluorometry and histological staining showed t...

journal_title：Bulletin of experimental biology and medicine

authors： Romanov YA,Darevskaya AN,Merzlikina NV,Buravkova LB

更新日期：2005-07-01 00:00:00

abstract：:We developed an optimal protocol for preparing and culturing of olfactory ensheathing cells from human olfactory mucosa. Using this protocol, we obtained a culture enriched with human olfactory ensheathing cells. Immunofluorescence analysis by simultaneous expression of GFAP and p75NTR markers showed that the content ...

journal_title：Bulletin of experimental biology and medicine

authors： Voronova АD,Stepanova OV,Valikhov MP,Chadin AV,Dvornikov АS,Reshetov IV,Chekhonin VP

更新日期：2018-03-01 00:00:00

abstract：:We studied the role of ryanodine receptors in the effects of hydrogen sulfide on transmitter release from frog motor nerve ending. Sodium hydrosulfide (300 μM), a donor of hydrogen sulfide, reversibly increased the frequency of miniature endplate current without changes in its amplitude-time parameters. These effects ...

journal_title：Bulletin of experimental biology and medicine

authors： Gerasimova EV,Yakovleva OV,Zefirov AL,Sitdikova GF

更新日期：2013-05-01 00:00:00

abstract：:The paper analyzes theoretical models of the adaptive modes of generation and stability of human heart as a nonlinear point source. The analysis encompasses only ECG time-domain dynamics. To solve the general problem of the study of the adaptive changes of the cardiosignal under the action of external periodic force a...

journal_title：Bulletin of experimental biology and medicine

authors： Pipin VV,Ragulskaya MV,Chibisov SM

更新日期：2010-10-01 00:00:00

abstract：:Polylactide degradation processes after its implantation into the subcutaneous fat of rats were studied by microscopy. After implantation polylactide was encapsulated in connective tissue. If a fragment of polylactide had sharp edges, injuring the tissue, a thick capsule formed with pronounced inflammatory infiltratio...

journal_title：Bulletin of experimental biology and medicine

authors： Maiborodin IV,Kuznetsova IV,Beregovoi EA,Shevela AI,Barannik MI,Maiborodina VI,Manaev AA

更新日期：2014-04-01 00:00:00

abstract：:Polymorphic variants of CYP1A2 and CYP2D6 genes of the cytochrome P450 system were studied in patients with schizophrenia with drug-induced motor disorders and hyperprolactinemia against the background of long-term neuroleptic therapy. We revealed an association of polymorphic variant C-163A CYP1A2*1F of CYP1A2 gene w...

journal_title：Bulletin of experimental biology and medicine

authors： Ivanova SA,Filipenko ML,Vyalova NM,Voronina EN,Pozhidaev IV,Osmanova DZ,Ivanov MV,Fedorenko OY,Semke AV,Bokhan NA

更新日期：2016-03-01 00:00:00

abstract：:We compared the effects of soluble products from the placenta obtained from women with normal pregnancy and pregnancy complicated by preeclampsia on cytokine secretion by THP-1 cells cultured on a 3D Matrigel scaffold. In the presence of soluble products from all placentas, the cells actively secreted IL-8, MCP-1, and...

journal_title：Bulletin of experimental biology and medicine

authors： Onokhina YS,L'vova TY,Tsitskarava DZ,Koren'kov DA,Sel'kov SA,Sokolov DI

更新日期：2014-02-01 00:00:00

abstract：:Experiments on rats showed that blockade of hyperpolarization-activated currents moderates tachycardia induced by beta-adrenoceptor agonist isoproterenol and potentiates the increase in stroke volume produced by this agonist. Electrical stimulation of the vagus nerve against the background of isoproterenol treatment a...

journal_title：Bulletin of experimental biology and medicine

authors： Zefirov TL,Ziyatdinova NI,Gainullin AA,Zefirov AL

更新日期：2002-05-01 00:00:00

abstract：:Conditions of human BM and umbilical cord blood MSC in vitro differentiation in the hepatogenic direction were studied. Changes in cell morphology, phenotype, acquisition of the capacity to produce albumin and accumulate glycogen, express cytokeratin, alkaline phosphatase, and albumin mRNA indicated that BM and umbili...

journal_title：Bulletin of experimental biology and medicine

authors： Kosmacheva SM,Seviaryn IN,Goncharova NV,Petyovka NV,Potapnev MP

更新日期：2011-05-01 00:00:00

abstract：:We studied the functional role of individual subtypes of muscarinic cholinoceptors in the pathogenesis of neuroleptic parkinsonism in rats. Blockade of M4 receptors prevented the development of extrapyramidal disorders, which was abolished by simultaneous blockade of M2 receptors. The data suggest that various subtype...

journal_title：Bulletin of experimental biology and medicine

authors： Dagaev SG,Fil'ko OA,Kubarskaya LG,Khrabrova AV,Mukovskii LA,Glukhova RI,Sanotskii VI,Dolgo-Saburov VB

更新日期：2004-05-01 00:00:00

abstract：:The dose-dependent effect of intranasal administration of antibodies to glutamate on acute generalized epileptic activity was studied in C57Bl/6 mice. It was shown that pretreatment with antibodies in doses of 100, 300, and 500 μg/kg 1 h before titration with convulsant pentylenetetrazole had anticonvulsant effects. T...

journal_title：Bulletin of experimental biology and medicine

authors： Karpova MN,Kuznetsova LV,Vetrile LA,Klishina NJ

更新日期：2013-07-01 00:00:00

abstract：:Parameters of cardiac activity after administration of the cholinesterase inhibitor physostigmine were analyzed in newborn rats and on day 16 of postnatal development. The type of cardiovascular response to acetylcholine excess in newborns and 16-day-old rats were similar, but they significantly differed by the magnit...

journal_title：Bulletin of experimental biology and medicine

authors： Sizonov VА,Dmitrieva LE

更新日期：2018-05-01 00:00:00

abstract：:Local application of ointment with Bacillus spp. strain MG8 (15,000-20,000 living bacterial cells), isolated from permafrost specimens, on the skin wound of about 60 mm(2) stimulated the reparation processes in experimental mice. A possible mechanism stimulating the regeneration of the damaged tissues under the effect...

journal_title：Bulletin of experimental biology and medicine

authors： Kalenova LF,Novikova MA,Subbotin AM

更新日期：2015-02-01 00:00:00

abstract：:Secretion and synthesis of vasopressin was studied in adult male Wistar rats receiving lipopolysaccharide in a dose of 250 microg/100 g body weight and subjected to moderate osmotic stimulation (2% NaCl perorally for 6 days). Lipopolysaccharide stimulated secretion of vasopressin into the blood. It should be emphasize...

journal_title：Bulletin of experimental biology and medicine

authors： Liskina EB,Grinevich VV,Volkova OV,Akmaev IG

更新日期：2003-08-01 00:00:00

abstract：:Ultrastructural characteristics of cell populations in the gastric tube mucosa were studied after plastic surgery for benign esophageal disease. The foveolar epithelium mainly consisted of secretory active mucocytes with small changes in cytoplasmic organelles. Functionally immature parietal cells and gland cells in t...

journal_title：Bulletin of experimental biology and medicine

authors： Lapii GA,Nepomnyashchikh LM,Sudovykh IE,Kutepov AV,Govorkov RV

更新日期：2011-02-01 00:00:00

abstract：:We studied etiologic structure of bacterial intestinal infections in monkeys of Adler nursery. A total of 533 monkeys with diarrhea syndrome and monkeys dead from intestinal infections, as well as clinically healthy monkeys and animals dead from other pathologies were examined by bacteriological and molecular-genetic ...

journal_title：Bulletin of experimental biology and medicine

authors： Ardasheliya SN,Kalashnikova VA,Dzhikidze EK

更新日期：2011-10-01 00:00:00

abstract：:The study examined maturation of preovulatory germinal vesicles oocytes (GV oocytes) induced by gonadotropic hormone PMSG in the inbred C57Bl/6J mice (viewed as a gold standard for diverse biomedical studies) as well as in the first generation hybrid C57Bl/6J×СВА/lac and СВА/lac×C57Bl/6J mice at various ages. The most...

journal_title：Bulletin of experimental biology and medicine

authors： Riabukha YA,Petrova DA,Zatsepina OV

更新日期：2019-09-01 00:00:00

abstract：:Enlargement of the brain weight was attained in rats by reducing the number of neonates in the litter. The brain of 14- and 30-day-old animals was examined (controls: intact animals from litters of average numbers). Difference between the brain weight at 14 and 30 days was about 200 mg. The parameter in the experiment...

journal_title：Bulletin of experimental biology and medicine

authors： Ryzhavskii BY,Litvintseva EM

更新日期：2012-11-01 00:00:00

abstract：:Melatonin administered to intact animals increased glutathione concentration and activities of glutathione peroxidase, glutathione reductase, NADP-isocitrate dehydrogenase, and glucose-6-phosphate dehydrogenase in the liver. In animals with toxic hepatitis melatonin treatment decreased glutathione concentration and en...

journal_title：Bulletin of experimental biology and medicine

authors： Pashkov AN,Popov SS,Semenikhina AV,Rakhmanova TI

更新日期：2005-05-01 00:00:00

abstract：:The effect of p-tyrosol on the spontaneous level of DNA damage in the cells of the bone marrow, liver, kidney, and rectum of mice (series I) and on the genotoxic effects of cytostatic drugs with different mechanisms of action in rat testicular cells (series II) was studied by DNA comet assay on C57BL/6 mice. p-Tyrosol...

journal_title：Bulletin of experimental biology and medicine

authors： Borovskaya TG,Vychuzhanina AV,Grigor'eva VA,Kollantay OV,Goldberg VE,Dygai AM

更新日期：2020-06-01 00:00:00

abstract：:In rat sinoatrial node, NAD(+) (10 μM) reduced the rate of spontaneous action potentials, duration of action potentials, and the velocity of slow diastolic depolarization, but the rate of action potential front propagation increases. In passed rabbit Purkinje fibers, NAD(+) (10 μM) reduced the duration of action poten...

journal_title：Bulletin of experimental biology and medicine

authors： Pustovit KB,Kuz'min VS,Sukhova GS

更新日期：2015-06-01 00:00:00

abstract：:Local inflammatory response in the lungs and fi brogenic potential of multi-walled carbon nanotubes were studied in an acute aspiration experiment in mice. The doses were chosen based on the concentration of nanotubes in the air at a workplace of the company-producer. ELISA, fl ow cytometry, enhanced darkfield microsc...

journal_title：Bulletin of experimental biology and medicine

authors： Khaliullin TO,Shvedova AA,Kisin ER,Zalyalov RR,Fatkhutdinova LM

更新日期：2015-03-01 00:00:00

abstract：:Pharmacokinetics of GVS-111, a new acylprolyldipeptide with nootropic properties and its penetration across the blood-brain barrier were studied in rats using HPLC. It was found that the dipeptide is absorbed in the gastrointestinal tract, enters the circulation, and penetrates through the blood-brain barrier in an un...

journal_title：Bulletin of experimental biology and medicine

authors： Boiko SS,Ostrovskaya RU,Zherdev VP,Korotkov SA,Gudasheva TA,Voronina TA,Seredenin SB

更新日期：2000-04-01 00:00:00

abstract：:The qualitative and quantitative differences in lipids composition were found in chromatin fractions differing by attachment to the nuclear matrix and transcriptional activity. During liver regeneration after partial hepatectomy Changes in the lipid spectrum of chromatin fractions in G1- and S-phases are associated wi...

journal_title：Bulletin of experimental biology and medicine

authors： Trofimov VA,Dudko AA

更新日期：2006-01-01 00:00:00

abstract：:Dihydroquercetin (flavonoid of plant origin) immobilized with an amino acid in lecithin nanoparticles promotes reduction of inflammatory reactions in the wound after thermal burn. The use of a liposomal complex in burn injury stabilizes endogenous antioxidant system and limits the secondary necrotic zone in the wounds...

journal_title：Bulletin of experimental biology and medicine

authors： Naumov AA,Shatalin YV,Potselueva MM

更新日期：2010-07-01 00:00:00

abstract：:Non-clonal and clonal abnormal cells (hypodiploid, polyploid, and with chromosome aberrations) were detected by the G-method in the bone marrow and blood of the majority of patients with non-Hodgkin lymphomas before therapy. The manifestation of these abnormalities changed individually after treatment. The most incide...

journal_title：Bulletin of experimental biology and medicine

authors： Ankina MA,Zavitaeva TA,Panferova TA,Shakhtarina SV,Pavlov VV

更新日期：2007-02-01 00:00:00

abstract：:The prooxidant-antioxidant balance in rats with oxidative stress was studied during correction of the L-arginine-NO system. Oxidative stress was induced by intravenous injection of E. coli lipopolysaccharide. Under conditions of oxidative stress the prooxidant-antioxidant imbalance was least pronounced during selectiv...

journal_title：Bulletin of experimental biology and medicine

authors： Glebov AN,Zinchuk VV

更新日期：2006-04-01 00:00:00