Hepatogenic potential of human bone marrow and umbilical cord blood mesenchymal stem cells.

abstract：:Carnosine significantly increased the number of spermatogonia and Sertoli cells in mice prone (SAMP1) and resistant (SAMR1) to accelerated aging and appreciably reduced cell yield in meiosis and spermiogenesis in SAMP1 mice. In experimental SAMP1 mice catastrophic changes in the number of gametes were paralleled by in...

journal_title：Bulletin of experimental biology and medicine

authors： Gopko AV,Kulibin AY,Semenova ML,Zakhidov ST

更新日期：2005-08-01 00:00:00

abstract：:The content of MMP-8 and MMP-9 in oral fluid of 145 patients (95 women and 50 men, 18-52 years) was measured by enzyme immunoassay. We examined 63 subjects with the intact periodontium and 82 patients with chronic generalized periodontitis (25 patients with mild disease, 45 patients with moderate disease, and 12 patie...

journal_title：Bulletin of experimental biology and medicine

authors： Kushlinskii NE,Solovykh EA,Karaoglanova TB,Bayar U,Gershtein ES,Troshin AA,Kostyleva OI,Grinin VM,Maksimovskaya LN,Yanushevitch OO

更新日期：2011-12-01 00:00:00

abstract：:We studied the effects of cholesterol, its oxidized derivatives mevalonate, and nuclear receptor agonists LXR, RXR, and FXR on the production of transforming growth factor-beta1 (TGF- beta1) by macrophages. After recruiting of macrophage monocytes into the focus of inflammation, the production of TGF-beta1 increased b...

journal_title：Bulletin of experimental biology and medicine

authors： Schwartz YSh,Khoshchenko OM,Dushkin MI,Feofanova NA

更新日期：2009-09-01 00:00:00

abstract：:Tropomyosin (Tpm) is one of the main regulatory proteins in the myocardium. In some heart pathologies, interchain disulfide crosslinking in the Tpm molecule occurs. In the ventricle, this change in the structural properties of the Tpm molecule affects calcium regulation of the actin-myosin interaction. Using an in vit...

journal_title：Bulletin of experimental biology and medicine

authors： Shchepkin DV,Matyushenko AM,Bershitsky SY,Kopylova GV

更新日期：2019-05-01 00:00:00

abstract：:The prooxidant-antioxidant balance in rats with oxidative stress was studied during correction of the L-arginine-NO system. Oxidative stress was induced by intravenous injection of E. coli lipopolysaccharide. Under conditions of oxidative stress the prooxidant-antioxidant imbalance was least pronounced during selectiv...

journal_title：Bulletin of experimental biology and medicine

authors： Glebov AN,Zinchuk VV

更新日期：2006-04-01 00:00:00

abstract：:The animals were adapted to intermittent hypoxic hypoxia in a flow pressure chamber for 3 days. Each one-day training session consisted of 4 elevations to an altitude of 6000 m for 20 min (15 m/sec, 20-min intervals between assents). Trekrezan (25 mg/kg intraperitoneally) was injected immediately after the end of dail...

journal_title：Bulletin of experimental biology and medicine

authors： Zarubina IV

更新日期：2008-01-01 00:00:00

abstract：:The content of phospholipids in various tissues was studied during synergistic interaction between two branches of the autonomic nervous system. We found higher myocardial content of choline-containing phospholipids and lower rigidity of erythrocyte membranes in rabbits with pronounced sympathetic potentiation of the ...

journal_title：Bulletin of experimental biology and medicine

authors： Lychkova AE,Smirnov VM

更新日期：2002-04-01 00:00:00

abstract：:We studied biocompatibility and bioresorption of 3D-printed polylactide and polyglycolide tissue membranes. Ultrasound microscopy and histological examination showed that membranes fabricated of a copolymer of lactic and glycolic acids in a mass ratio of 1:9 are bioresorbed and have good biocompatibility with soft tis...

journal_title：Bulletin of experimental biology and medicine

authors： Kim EV,Petronyuk YS,Guseynov NA,Tereshchuk SV,Popov AA,Volkov AV,Gorshenev VN,Olkhov AA,Levin VM,Dymnikov AB,Rodionov VE,Tumanyan GA,Ivashkevich SG,Bonartsev AP,Borozdkin LL

更新日期：2021-01-01 00:00:00

abstract：:The influence of a new 2-mercaptobenzimidazole derivative afobazole on cytogenetic effects of dioxidine and cyclophosphamide was studied by counting chromosome aberrations in bone marrow cells of C57Bl/6 mice. Afobazole (1-100 mg/kg perorally) exhibited antimutagenic activity determined by its antioxidant properties. ...

journal_title：Bulletin of experimental biology and medicine

authors： Zhanataev AK,Durnev AD,Seredin SB

更新日期：2000-11-01 00:00:00

abstract：:We studied the effect of extracellular purine nucleotides (NAD+ and ATP) on spontaneous arrhythmogenic activity caused by norepinephrine in myocardial sleeves of pulmonary veins. In pulmonary veins, NAD+ and ATP reduced the frequency of action potentials and their duration at regular type of spontaneous activity cause...

journal_title：Bulletin of experimental biology and medicine

authors： Karimova VM,Pustovit KB,Abramochkin DV,Kuz'min VS

更新日期：2017-03-01 00:00:00

abstract：:Human umbilical cord represents a source of multipotent stromal cells of a supreme therapeutic potential. The cells can be isolated from either fresh or cryopreserved umbilical cord tissues. DMSO is a cryoprotectant most commonly used for preservation of umbilical cord tissues; however, cyto- and genotoxicity of this ...

journal_title：Bulletin of experimental biology and medicine

authors： Arutyunyan IV,Strokova SО,Makarov АV,Mullabaeva SМ,Elchaninov АV,Lokhonina АV,Abramov АА,Fatkhudinov ТK

更新日期：2018-11-01 00:00:00

abstract：:Morphological changes in the thymus of female Wistar rats with experimental mammary gland carcinomas were studied. After adjuvant therapy, the area of the cortical matter and density of parenchymal cells in the thymus decreased, while areas of the medulla, connective tissue, and content of immunoblasts and macrophages...

journal_title：Bulletin of experimental biology and medicine

authors： Kazakov OV,Kabakov AV,Poveshchenko AF,Ishchenko IY,Poveshchenko OV,Strunkin DN,Raiter TV,Michurina SV,Konenkov VI

更新日期：2017-03-01 00:00:00

abstract：:We studied changes in cell cycle and apoptosis in normal keratinocytes and melanocytes after exposure to UV-B radiation. UV-B radiation modulated proliferation rate in the studied cell and produced an apoptosis-modulating effect in epidermal melanocytes. ...

journal_title：Bulletin of experimental biology and medicine

authors： Ruksha TG

更新日期：2009-05-01 00:00:00

abstract：:Study was performed by counting cells with chromosomal aberrations in C57Bl/6 mice. Bark dry extract was given perorally in doses of 50, 150, 450, and 1500 mg/kg. Mutagens dioxidine and cyclophosphamide were injected intraperitoneally in doses of 200 and 20 mg/kg, respectively. Bark dry extract in doses of 150 and 150...

journal_title：Bulletin of experimental biology and medicine

authors： Zhanataev AK,Presnova GA,Chistyakov AN,Durnev AD

更新日期：2004-11-01 00:00:00

abstract：:We studied the influence of pretreatment with chemical mildronate analogue sibusol on the course of experimental gastric ulcer in rats. Sibusol produced a protective effects on the stomach and duodenum. ...

journal_title：Bulletin of experimental biology and medicine

authors： Lychkova AE,Savchuk VI,Smirnov VM

更新日期：2004-01-01 00:00:00

abstract：:Non-pulsed optical density of the small intestine was studied in 32 dogs and the results were compared with the data of angiotensometry and pulsomotorography. New regularities of blood circulation in the small intestine were detected: more than half of the total volume specific blood flow in the intestinal tissue is n...

journal_title：Bulletin of experimental biology and medicine

authors： Zhizhin FS,Tochilov SL,Chuchkov VM

更新日期：2003-11-01 00:00:00

abstract：:Acute experiments on cats showed that dynorphin A(1-13) modulates pulse activity of afferent neurons and interneurons in the bulbar cardiovascular center against the background of stable blood pressure. ...

journal_title：Bulletin of experimental biology and medicine

authors： Mikhailova SD,Vasil'eva TV,Semushkina TM,Storozhakov GI

更新日期：2003-01-01 00:00:00

abstract：:We studied the role of insulin-like growth factors 1 and 2 (IGF-1 and IGF-2) in functional differentiation of HC11 mouse mammary gland cells. It was found that both IGF-1 and IGF-2 activate the expression of milk protein β-casein in the presence of prolactin and hydrocortisone. It was found that β-casein expression is...

journal_title：Bulletin of experimental biology and medicine

authors： Shushanov SS

更新日期：2011-12-01 00:00:00

abstract：:The effects of LPS from E. coli on DNA-binding activities of PPARα and PPARγ in the liver and immune system parameters of were studied in hypertensive ISIAH rats and normotensive WAG rats. In ISIAH rats characterized by low basal level of PPARα, PPARγ, and HDL, the response of the peripheral immune system compartment ...

journal_title：Bulletin of experimental biology and medicine

authors： Shurligina AV,Dushkin MI,Melnikova EV,Panteleeva NG,Tenditnik MV,Chrapova MV,Trufakin VA

更新日期：2013-08-01 00:00:00

abstract：:The myogenic differentiation capacity of prenatal mesenchymal stem cells from the main sites of hemopoiesis (bone marrow, thymus, liver, and spleen) was studied. Myogenesis was observed in all studied cell cultures except splenic mesenchymal stem cells. Differentiating cells from the thymus, bone marrow, and liver wer...

journal_title：Bulletin of experimental biology and medicine

authors： Gornostaeva SN,Rzhaninova AA,Gol'dstein DV

更新日期：2006-04-01 00:00:00

abstract：:Taurine is an important endogenous agonist of glycine receptors (GlyR). Using the patchclamp technique, we measured chloride current induced by a short (600 msec) application of taurine (ITau) on isolated rat pyramidal neurons. pH of taurine solution in the applicator pipette was neutral (7.4) or acidic (7.0-5.0). App...

journal_title：Bulletin of experimental biology and medicine

authors： Solntseva EI,Bukanova YV,Kondratenko RV,Skrebitsky VG

更新日期：2019-06-01 00:00:00

abstract：:We studied the effects of neurotensin dipeptide analog Dilept (N-caproyl-L-prolyl-L-tyrosine methyl ester) on dopamine metabolism and synthesis in the nucleus accumbens of Wistar rats. Dilept increased the levels of dopamine and its metabolites (homovanillic acid and dioxyphenylalanine) and stimulated dopamine turnove...

journal_title：Bulletin of experimental biology and medicine

authors： Shubenina EV,Kudrin VS,Klodt PM,Narkevich VB,Kuznetsova EA,Gudasheva TA,Ostrovskaya RU

更新日期：2012-09-01 00:00:00

abstract：:The effects of a new thietanylbenzimidazole derivative (K-134) on estrous cycles, conception processes, and sexual behavior of female rats were studied. Two-week oral treatment with K-134 in doses of 5 and 50 mg/kg shortened the estrus phase and prolonged proestrus. Changes in sexual behavior were presented by activat...

journal_title：Bulletin of experimental biology and medicine

authors： Kuzubova EA,Bugaeva LI,Sergeeva SA,Petrov VI,Kataev VA,Kharlamov IV,Mal'tsev MV

更新日期：2015-09-01 00:00:00

abstract：:Apoptosis markers (p53, PUMA, p21, and Mdm2) were studied in patients with rheumatoid arthritis at the early and late stages of disease on bone marrow smears and frozen sections of the articular synovial membrane. The target molecules were found in all patients. The early stage was characterized by maximum expression ...

journal_title：Bulletin of experimental biology and medicine

authors： Doroshevskaya AY,Kondratovskii PM,Dubikov AI,Eliseikina MG

更新日期：2014-01-01 00:00:00

abstract：:Treatment with a combination of artrofoon and anaferon significantly reduced clinical and laboratory parameters of rheumatoid inflammation and significantly decreased the content of antiinflammatory cytokines in the blood. These findings attest to antiinflammatory and immunomodulating effects of these preparations. ...

journal_title：Bulletin of experimental biology and medicine

authors： Petrov VI,Babaeva AR,Solodenkova KS,Cherevkova EV,Zabolotneva YA,Kachanova MV,Sergeeva SA

更新日期：2009-09-01 00:00:00

abstract：:Rarely repeated episodes of 1-h immobilization in rats were accompanied by an increase in the content of molecular products of lipid peroxidation and decrease in the amount of oxidatively modified proteins. Monoamine oxidase B inhibitor deprenyl prevented the poststress activation of lipid peroxidation. ...

journal_title：Bulletin of experimental biology and medicine

authors： Tseilikman VE,Sinitsky AI,Poyarkov KA,Vojdaev EV

更新日期：2009-12-01 00:00:00

abstract：:The incidence of breast tumor in inbred C3H-A mice (virgin female) from hyperthyroid, hypothyroid, and euthyroid control groups at week 44 of the experiment was 86.67, 30, and 62.5%, respectively. The percentage of metastatic lymph nodes in these groups was 65.9±16.7, 35.9±5.9, and 53.9±7.2%, respectively (p<0.005). I...

journal_title：Bulletin of experimental biology and medicine

authors： Glushakov RI,Proshin SN,Tapil'skaya NI

更新日期：2013-12-01 00:00:00

abstract：:Reversible cerebral ischemia of medium severity was reproduced in male Wistar rats by bilateral occlusion of the common carotid arteries. Solid-phase structures (anisomorphons) were obtained by marginal dehydration of the serum. Small focal isotropic defects in the serum anisomorphon texture were found in 100% cases d...

journal_title：Bulletin of experimental biology and medicine

authors： Shatokhina SN,Aleksandrin VV,Shatokhina IS,Kubatiev AA,Shabalin VN

更新日期：2018-01-01 00:00:00

abstract：:Spontaneous and stimulated reaction of lymphocyte proliferation and blood levels of CD25- and CD120-expressing lymphocytes were studied in patients with autoimmune thyroiditis and diffuse toxic goiter. Activation of CD25- and CD120-presenting function of blood lymphocytes was revealed. The findings indicate that the c...

journal_title：Bulletin of experimental biology and medicine

authors： Urazova OI,Kravets EB,Nedosekova YV,Rogaleva AV,Kuznecova VN,Rumpel OA

更新日期：2008-09-01 00:00:00

abstract：:Comparative analysis of the state of the thymus, activity of cell component of the immune system, and open field behavior of Wistar and OXYS rats showed early involution of the thymus in OXYS rats. By morphological picture this involution corresponded to accidental involution and was paralleled by low level of delayed...

journal_title：Bulletin of experimental biology and medicine

authors： Markova EV,Obukhova LA,Kolosova NG

更新日期：2003-12-01 00:00:00