Abstract:
:Morphological changes in the thymus of female Wistar rats with experimental mammary gland carcinomas were studied. After adjuvant therapy, the area of the cortical matter and density of parenchymal cells in the thymus decreased, while areas of the medulla, connective tissue, and content of immunoblasts and macrophages increased. In the thymuses of rats receiving exogenous DNA, morphological signs of activation of the lymphoid and epithelial components were found: areas of the cortex and medulla, glandular and connective tissue corresponded to the values in intact animals, the counts of lymphocytes in the central part of the cortical matter and of macrophages in all zones of the thymus increased, and lymphocyte migration from the thymus increased (in comparison with the chemotherapy group).
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Kazakov OV,Kabakov AV,Poveshchenko AF,Ishchenko IY,Poveshchenko OV,Strunkin DN,Raiter TV,Michurina SV,Konenkov VIdoi
10.1007/s10517-017-3680-7subject
Has Abstractpub_date
2017-03-01 00:00:00pages
654-657issue
5eissn
0007-4888issn
1573-8221pii
10.1007/s10517-017-3680-7journal_volume
162pub_type
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