Efficiency of enzyme-inducing agents in rats with intrahepatic cholestasis.

abstract：:Phenibut and its derivatives normalized cellular (index of delayed-type hypersensitivity reaction) and humoral (antierythrocyte antibody titer) immunity and the lymphoproliferative processes in immunocompetent organs of animals with cyclophosphamide-induced immunosuppression. This indicates pronounced immunocorrective...

journal_title：Bulletin of experimental biology and medicine

authors： Tyurenkov IN,Samotrueva MA

更新日期：2009-05-01 00:00:00

abstract：:Fragments of the dorsolateral wall of the anterior brain vesicle from rat embryos on embryonic day 15 were dissociated and the resultant suspension containing single cells and cell aggregates was injected into the proximal segment of crushed sciatic nerve of adult animals for evaluation of their engrafting and differe...

journal_title：Bulletin of experimental biology and medicine

authors： Petrova ES,Isaeva EN,Korzhevskii DE

更新日期：2013-11-01 00:00:00

abstract：:Function of sarcoplasmic reticulum was studied in rat papillary muscles treated with amiodarone. An extra stimulus (0.5 Hz) was delivered to the muscle 0.225 sec after application of a regular stimulus. Postextrasystolic potentiation was evaluated in control myocardial samples and samples treated with amiodarone. The ...

journal_title：Bulletin of experimental biology and medicine

authors： Afanas'ev SA,Lukavskaya IA,Kandinskii ML,Medvedev MA

更新日期：2002-03-01 00:00:00

abstract：:The mechanism of antiischemic effect of low-energy laser radiation was studied in rats with experimental myocardial infarction taking into consideration the effect of laser on hemoglobin affinity for oxygen and intensity of lipid peroxidation. Low-energy laser irradiation for 15 min in vitro decreased the area of myoc...

journal_title：Bulletin of experimental biology and medicine

authors： Gatsura SV,Gladkikh SP,Titov MN

更新日期：2004-04-01 00:00:00

abstract：:Morphological signs of early interstitial fibrosis, developing under conditions of acute viral inflammation (postinfection days 1-14), were observed in C57Bl/6 mice infected with influenza A/H5N1 A/goose/Krasnoozerskoye/627/05 virus. The development of fibrosis was confirmed by an increase in the number of lung cells ...

journal_title：Bulletin of experimental biology and medicine

authors： Anikina AG,Shkurupii VA,Potapova OV,Kovner AV,Shestopalov AM

更新日期：2014-04-01 00:00:00

abstract：:The antidepressant, psychostimulant, and nootropic effects of a composition of major and trace elements including KCl, RbNO3, magnesium sulfate, and zinc sulfate were studied on the models of behavioural despair (Porsolt test) and conditioned passive avoidance test. The preparation was found to shorten the immobilizat...

journal_title：Bulletin of experimental biology and medicine

authors： Afanasieva OG,Suslov NI,Shilova IV

更新日期：2013-06-01 00:00:00

abstract：:Study was performed by counting cells with chromosomal aberrations in C57Bl/6 mice. Bark dry extract was given perorally in doses of 50, 150, 450, and 1500 mg/kg. Mutagens dioxidine and cyclophosphamide were injected intraperitoneally in doses of 200 and 20 mg/kg, respectively. Bark dry extract in doses of 150 and 150...

journal_title：Bulletin of experimental biology and medicine

authors： Zhanataev AK,Presnova GA,Chistyakov AN,Durnev AD

更新日期：2004-11-01 00:00:00

abstract：:The relative content of myocyte-active factors and endogenous muscarinic receptor blocker in the blood increased, while the concentration of endogenous beta-adrenoceptor sensitizer decreased in coronary patients with a history of acute myocardial infarction. Physical training produced a therapeutic effect, normalized ...

journal_title：Bulletin of experimental biology and medicine

authors： Tsirkin VI,Nozdrachev AD,Sizova EN,Mal'chikova SV,Gulyaeva SF

更新日期：2003-07-01 00:00:00

abstract：:The development of dissociated cells from rat embryonic spinal ganglion after transplantation to damaged nerve of adult animals was studied using immunohistochemical differentiation markers of neural and glial cells. The cell suspension obtained after dissociation of rat embryonic spinal ganglia (embryonic day 15) was...

journal_title：Bulletin of experimental biology and medicine

authors： Petrova ES,Isaeva EN,Korzhevskii DE

更新日期：2014-09-01 00:00:00

abstract：:We studied the correlation between the rank and age of baboons (n=12) with their cognitive abilities. A positive correlation was found between performances of different tests by male. The ability to solve the tests related to bait placement depended on the age of the males and age-related hierarchical status. Four-yea...

journal_title：Bulletin of experimental biology and medicine

authors： Anikaev AE,Chalyan VG,Meishvili NV

更新日期：2018-08-01 00:00:00

abstract：:Anticonvulsant activity and pharmacokinetics of nanoemulsion and unmodified substance of carbamazepine were compared in experiments on mice. Carbamazepine nanoemulsion demonstrated significant anticonvulsant activity and was superior to unmodified substance of carbamazepine against seizures induced by maximum electric...

journal_title：Bulletin of experimental biology and medicine

authors： Prokhorov DI,Sariev AK,Abramov DA,Voronina TA,Kapitsa IG,Zhuravko AS,Shiriaeva MV,Kaplun AP,Seifulla RD

更新日期：2014-10-01 00:00:00

abstract：:The dependence of daily vitamin excretion with breast milk on dietary vitamin content and blood vitamin level was studied in nursing women. Breast mils vitamins were assayed in women supplied with vitamins. We identified the criteria for adequate vitamin supply in nursing women over the 1st month after labor (vitamins...

journal_title：Bulletin of experimental biology and medicine

authors： Kodentsova VM,Vrzhesinskaya OA

更新日期：2006-03-01 00:00:00

abstract：:Efficiency and mechanisms of action of photodynamic therapy of M-1 sarcoma were studied experimentally on rats using photodithazine, a novel chlorine photosensitizer. The tissue and cellular targets for this agent are vascular wall, plasma membrane of tumor cells, and intracellular structures responsible for prolifera...

journal_title：Bulletin of experimental biology and medicine

authors： Romanko YS,Tsyb AF,Kaplan MA,Popuchiev VV

更新日期：2004-12-01 00:00:00

abstract：:We studied carbohydrate specificity and isotypes of antibodies to BSA-conjugated tetrasaccharide, a repeating unit of the capsular polysaccharide of Streptococcus pneumoniae serotype 14, in mouse polyclonal sera and hybridoma-synthesized products. Natural IgM antibodies to the tetrasaccharide containing epitopes simil...

journal_title：Bulletin of experimental biology and medicine

authors： Kurbatova ЕА,Yakovleva IV,Akhmatova EА,Sukhova ЕV,Yashunsky DV,Tsvetkov YE,Nifantiev NE

更新日期：2019-02-01 00:00:00

abstract：:Oxygen-dependent processes in peripheral blood monocytes were intensified in patients with metabolic cardiovascular syndrome. This was manifested in increased production of O(2)(*-) and NO. Among metabolic factors (cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triacylglycerols...

journal_title：Bulletin of experimental biology and medicine

authors： Suslova TE,Gruzdeva OV,Fedorova TS,Karpov RS

更新日期：2004-05-01 00:00:00

abstract：:Morphometric analysis of structural and functional changes in the human mesenteric lymph nodes during aging revealed the development of fibrous connective tissue, fragmentation of the lymphoid parenchyma, the absence of follicles with germinal centers, and a decrease in the level of lymphocyte proliferation, which was...

journal_title：Bulletin of experimental biology and medicine

authors： Erofeeva LM,Mnikhovich MV

更新日期：2020-03-01 00:00:00

abstract：:The content of catecholamines and their metabolites in the brain and the relationship between cerebral catecholamine levels and their urinary excretion were studied in rats with 6-OHDA-induced hemiparkinsonism. 6-OHDA reduced brain concentrations of dopamine, DOPAC, and homovanilic acid and urinary excretion of dopami...

journal_title：Bulletin of experimental biology and medicine

authors： Chekhonin VP,Baklaushev VP,Kogan BM,Savchenko EA,Lebedev SV,Man'kovskaya IV,Filatova TS,Yusupova IU,Dmitrieva TB

更新日期：2000-08-01 00:00:00

abstract：:The myogenic differentiation capacity of prenatal mesenchymal stem cells from the main sites of hemopoiesis (bone marrow, thymus, liver, and spleen) was studied. Myogenesis was observed in all studied cell cultures except splenic mesenchymal stem cells. Differentiating cells from the thymus, bone marrow, and liver wer...

journal_title：Bulletin of experimental biology and medicine

authors： Gornostaeva SN,Rzhaninova AA,Gol'dstein DV

更新日期：2006-04-01 00:00:00

abstract：:A reproducible model of fetal liver regeneration was created. Resection of 20% liver was carried out in rat fetuses on day 17 of prenatal development. The organ weight was restored after 2 days at the expense of an increase in hepatocyte mitotic activity; cell hypertrophy was minor. After recovery, the cell compositio...

journal_title：Bulletin of experimental biology and medicine

authors： Elchaninov AV,Bolshakova GB

更新日期：2011-01-01 00:00:00

abstract：:Blood flow in reproductive organs was studied during experimental cessation of blood outflow in the testicular vein. This pathological state was accompanied by disturbances of the complex pathogenesis. The major component was autoregulatory focal ischemia, which resulted from the venoarterial response to venous hypert...

journal_title：Bulletin of experimental biology and medicine

authors： Artifeksov SB,Artyukhin AA

更新日期：2007-06-01 00:00:00

abstract：:During left-ventricular myocardial ischemia, the decrease in the venous return is determined by reduction of cardiac output, which results from heart rate deceleration and decrease in left-ventricular stroke volume. The latter is related to a decrease in myocardial contractility and blood storage in the pulmonary circ...

journal_title：Bulletin of experimental biology and medicine

authors： Evlakhov VI,Poyassov IZ

更新日期：2012-02-01 00:00:00

abstract：:We proposed a mathematical model and estimated the parameters of adsorption of albumin-bilirubin complex to the surface of carbon pyropolymer. Design data corresponded to the results of experimental studies. Our findings indicate that modeling of this process should take into account fractal properties of the surface ...

journal_title：Bulletin of experimental biology and medicine

authors： Nikolaev AV,Rozhilo YA,Starozhilova TK,Sarnatskaya VV,Yushko LA,Mikhailovskii SV,Kholodov AS,Lobanov AI

更新日期：2005-09-01 00:00:00

abstract：:High basal production of primary active oxygen forms was detected in the peripheral blood neutrophils of patients with renal cell cancer. In vitro stimulation of neutrophils led to more rapid release of superoxide radicals into extracellular space and to a reduction of cell capacity to more intense production of prima...

journal_title：Bulletin of experimental biology and medicine

authors： Shkapova EA,Kurtasova LM,Savchenko AA

更新日期：2010-08-01 00:00:00

abstract：:We studied the effects of ionophores on activity of Na+,Cl-(HCO 3- )-ATPase. The most significant effect on the activity of this enzyme was produced by protonophore 2,4-dinitrophenol. The effect of this drug largely depended on the cation and anion composition and pH of the incubation medium and its pH. Activity of Na...

journal_title：Bulletin of experimental biology and medicine

authors： Yurkiv VA,Melikhov VI,Shubin VS

更新日期：2016-10-01 00:00:00

abstract：:We studied the effects of potentiated antibodies to morphine and mu-opioid receptors on animal behavior in the forced swimming test and reaction of light avoidance after morphine withdrawal. Antibodies to morphine normalized behavioral characteristics in the forced swimming test, while antibodies to mu-opioid receptor...

journal_title：Bulletin of experimental biology and medicine

authors： Pavlov IF,Epstein OI,Shtark MB

更新日期：2003-01-01 00:00:00

abstract：:Carbacholine reduced, while baclofen and norepinephrine increased resting membrane potential in earthworm somatic muscle cells. In the presence of carbacholine, neither norepinephrine, nor baclofen hyperpolarized the membrane. Ouabain decreased resting potential and abolished the effects of carbacholine, norepinephrin...

journal_title：Bulletin of experimental biology and medicine

authors： Volkov EM,Sabirova AR,Volkov ME,Zefirov AL

更新日期：2007-08-01 00:00:00

abstract：:The linear parameters and number of Langerhans islets were evaluated in rats with alloxaninduced diabetes mellitus after transplantation of fetal pancreatic tissue to the anterior chamber of the eye. The islets significantly increased in size by week 3 after surgery and a trend to an increase in their number was obser...

journal_title：Bulletin of experimental biology and medicine

authors： Kulikov DA,Kulikov AV,Arkhipova LV,Smirnova GN,Dreval' AV,Tikhonova LP,Gaivoronskii IV,Sukhikh GT

更新日期：2015-01-01 00:00:00

abstract：:Psychoimmune interactions were studied in women of reproductive age with endometriosis. Pronounced immunological shifts manifested in a shift of the T-cellular immunity, resulting in imbalanced production of pro- (IL-1β, IL-2, IFN-γ) and anti-inflammatory (IL-4) cytokines. Significant correlations between the severity...

journal_title：Bulletin of experimental biology and medicine

authors： Nasyrova RF,Sotnikova LS,Baystrukova NV,Krivoschchekova GV,Novitsky VV,Kupriyanova IE,Semke VY,Naslednikova IO,Baykov AN

更新日期：2011-11-01 00:00:00

abstract：:The effect of streptozotocin-induced diabetes mellitus on some parameters of energy metabolism and functional status of cell membranes was studied in experiments on rats. It was found that the development of diabetes mellitus is associated with dramatic changes in the metabolism of blood cells and kidney tissue: inhib...

journal_title：Bulletin of experimental biology and medicine

authors： Mikaelian NP,Gurina AE,Terent'ev AA

更新日期：2013-03-01 00:00:00

abstract：:Antiaggregant activity of a new tricyclic benzimidazole derivative, RU-891 compound, was studied on the model of ADP-induced platelet aggregation in vitro and intravascular platelet aggregation in vivo. We evaluated the effect of this substance on blood coagulation potential. Antiaggregant agent acetylsalicylic acid w...

journal_title：Bulletin of experimental biology and medicine

authors： Kucheryavenko AF,Spasov AA,Petrov VI,Anisimova VA

更新日期：2014-04-01 00:00:00