Abstract:
:The antidepressant, psychostimulant, and nootropic effects of a composition of major and trace elements including KCl, RbNO3, magnesium sulfate, and zinc sulfate were studied on the models of behavioural despair (Porsolt test) and conditioned passive avoidance test. The preparation was found to shorten the immobilization time in the Porsolt test and promote retention of the conditioned passive avoidance. The most pronounced psychostimulant effect of the substance was observed at a dose of 4.68 mg/kg and the most pronounced antidepressant effect was found at a dose of 18.72 mg/kg. Maximum nootropic activity of the preparation was found at a dose of 93.6 mg/kg.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Afanasieva OG,Suslov NI,Shilova IVdoi
10.1007/s10517-013-2113-5subject
Has Abstractpub_date
2013-06-01 00:00:00pages
204-6issue
2eissn
0007-4888issn
1573-8221journal_volume
155pub_type
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