Relaxing Effect of Hydrogen Sulfide on Isolated Bovine Mesenteric Lymph Nodes.

abstract：:Phenibut and its derivatives normalized cellular (index of delayed-type hypersensitivity reaction) and humoral (antierythrocyte antibody titer) immunity and the lymphoproliferative processes in immunocompetent organs of animals with cyclophosphamide-induced immunosuppression. This indicates pronounced immunocorrective...

journal_title：Bulletin of experimental biology and medicine

authors： Tyurenkov IN,Samotrueva MA

更新日期：2009-05-01 00:00:00

abstract：:The local anaphylactic reaction and the effects of histamine during blocking of the slow sodium-calcium channels by isoptine were investigated in the spontaneously contracting oracle of the atrium of a guinea pig previously sensitized to egg albumin. Simultaneously with the intracellular recording of the potentials, i...

journal_title：Bulletin of experimental biology and medicine

authors： Khodorov BI,Voronovitskii EG,Ignat'eva VB

更新日期：1975-01-01 00:00:00

abstract：:Acute experiments on cats showed that injection of catecholamines induced unidirectional shifts in right and left atrial pressure in 70% cases (these shifts were positive in one half of cats and negative in the other half). In 30% cases, the left and right atrial pressures changed in opposite direction: right atrial p...

journal_title：Bulletin of experimental biology and medicine

authors： Tkachenko BI,Evlakhov VI,Poyasov IZ

更新日期：2005-01-01 00:00:00

abstract：:Comparative analysis of the parameters of LPO, antioxidant defense (AOD), and the thiol/disulfide system was performed in fertile and infertile males of reproductive age carrying different genotypes of the glutathione system genes. Blood plasma, blood hemolysate, and ejaculate served as specimens for biochemical studi...

journal_title：Bulletin of experimental biology and medicine

authors： Kolesnikova LI,Kurashova NA,Bairova TA,Dolgikh MI,Ershova OA,Natyaganova LV,Dashiev BG,Gutnik IN,Koroleva NV

更新日期：2017-07-01 00:00:00

abstract：:Noopept, a peptide analog of piracetam, enhanced phagocytic activity of mouse peritoneal macrophages, stimulated humoral and cellular immune response to various antigens, and markedly increased spontaneous proliferative activity of splenocytes. In animals with secondary immune deficiency caused by cyclophosphamide, no...

journal_title：Bulletin of experimental biology and medicine

authors： Kovalenko LP,Shipaeva EV,Alekseeva SV,Pronin AV,Durnev AD,Gudasheva TA,Ostrovskaja RU,Seredenin SB

更新日期：2007-07-01 00:00:00

abstract：:Intraperitoneal injections of hexavalent chromium (sodium bichromate) in the concentrations of 0.025 μg/kg (10-fold lower than MAC; group 1) and 2.5 μg/kg (10-fold higher than MAC; group 2) to rats in a subacute experiment caused dose-dependent morphological changes in the thymus: increased the counts of cells in a st...

journal_title：Bulletin of experimental biology and medicine

authors： Zhumabaeva AN,Zarishnyak NV,Bekmukhambetov EZh

更新日期：2014-02-01 00:00:00

abstract：:We revealed a significant positive correlation between the concentrations of tissue VEGF and its receptor VEGFR2 in the primary tumor. The degree and direction of changes in the content of VEGF and VEGFR2 in cytosols of tumors from patients with locally spread breast cancer during the preoperation therapy depended on ...

journal_title：Bulletin of experimental biology and medicine

authors： Kim EA,Gershtein ES,Vysotskaya IV,Kushlinskii NE

更新日期：2008-02-01 00:00:00

abstract：:Non-pulsed optical density of the small intestine was studied in 32 dogs and the results were compared with the data of angiotensometry and pulsomotorography. New regularities of blood circulation in the small intestine were detected: more than half of the total volume specific blood flow in the intestinal tissue is n...

journal_title：Bulletin of experimental biology and medicine

authors： Zhizhin FS,Tochilov SL,Chuchkov VM

更新日期：2003-11-01 00:00:00

abstract：:We studied anti-ischemic activity of n-tyrozol under conditions of repeated transient myocardial ischemia in rats caused by repeated (5×3 min) occlusion of the left coronary artery. n-Tyrozol administered intraperitoneally in a dose of 20 mg/kg daily over 4 days before the ischemia modeling (the last injection 15 min ...

journal_title：Bulletin of experimental biology and medicine

authors： Plotnikov MB,Chernysheva GA,Smol'yakova VI,Plotnikova TM,Sysolyatin SV,Kryukov YA

更新日期：2018-09-01 00:00:00

abstract：:We studied the effects of optical (dd-, ll-, dl-, and ld-dipeptides with alpha-bond, EW) structural isomers and cyclic (dd-, ll-, dl-, and ld-dipeptides with gamma-bond, iEW) analogs of Glu-Trp synthetic dipeptide on the population of normal hemopoietic stem cells. Dipeptides containing lGlu (lGlu-lTrp, lGlu-dTrp) inj...

journal_title：Bulletin of experimental biology and medicine

authors： Semina OV,Semenets TN,Zamulaeva IA,Selivanova EI,Malyutina YV,Saenko AS,Deigin VI

更新日期：2006-02-01 00:00:00

abstract：:We performed immunohistochemical analysis of the expression of TGFβ, galectin-1, vimentin, and thrombospondin in the mucosa in gastric cancer of diffuse and intestinal type associated with systemic undifferentiated connective tissue dysplasia. In diffuse gastric cancer, both with and without association with connectiv...

journal_title：Bulletin of experimental biology and medicine

authors： Naumova LA,Osipova ON,Klinnikova MG

更新日期：2019-04-01 00:00:00

abstract：:Nanocrystalline particles of chitin in the form of hydrosol in a concentration of 0.63 mg/ml have no effect on aggregation of human platelets and clotting time of platelet-poor plasma in coagulation tests. ADP-induced aggregation of human platelets was inhibited by these nanoparticles in concentrations of 0.63 and 1.0...

journal_title：Bulletin of experimental biology and medicine

authors： Drozd NN,Torlopov MA,Udoratina EV,Logvinova YS

更新日期：2018-04-01 00:00:00

abstract：:Hemopoietic islets, associations of stromal (macrophages, fibroblasts) and blood (including stem) cells, are structural and functional units of the bone marrow. We studied cellular and molecular processes developing following short-term (1 h) contact of hemopoietic islets with ferromagnetic nanoparticles in a multicel...

journal_title：Bulletin of experimental biology and medicine

authors： Novitsky VA,Khlusov IA,Ryazantseva NV,Chechina OE,Feduschak TA,Ermakov AE,Uimin MA

更新日期：2011-08-01 00:00:00

abstract：:Enlargement of the brain weight was attained in rats by reducing the number of neonates in the litter. The brain of 14- and 30-day-old animals was examined (controls: intact animals from litters of average numbers). Difference between the brain weight at 14 and 30 days was about 200 mg. The parameter in the experiment...

journal_title：Bulletin of experimental biology and medicine

authors： Ryzhavskii BY,Litvintseva EM

更新日期：2012-11-01 00:00:00

abstract：:The concentrations of the key factors of molecular pathogenesis of prehypertension (angiotensin II, HLDF24, S100b, endothelin, autoantibodies to these molecules, and VEGF) were analyzed in subjects with optimal BP (<120/80 mm Hg) and prehypertension (120-139/80-89 mm Hg). Comparative and correlation analysis of the le...

journal_title：Bulletin of experimental biology and medicine

authors： Sherstnev VV,Gruden MA,Karlina VP,Ryzhov VM,Kuznetsova AV,Senko OV

更新日期：2020-01-01 00:00:00

abstract：:We studied the influence of the characteristics of oxide porous coatings on osteogenesis and integration of new bone tissue and titanium implant surface in the ectopic osteogenesis test. Implants with coating with pore size 2-20 μ exhibit better osteogenic and osteoconductive characteristics than implants with homogen...

journal_title：Bulletin of experimental biology and medicine

authors： Nadezhdin SV,Zubareva EV,Burda YE,Kolobov YR,Ivanov MB,Khramov GV,Afanas'ev AY

更新日期：2017-04-01 00:00:00

abstract：:Characteristics of distribution of cholinergic and adrenoceptor structures along the sinoatrial node artery in rat heart were evaluated by autoradiography on semithin sections by determining the density of (3)H-dihydroalprenolol and (3)H-quinuclidinyl benzilate binding sites. The relative density of binding sites for ...

journal_title：Bulletin of experimental biology and medicine

authors： Sutyagin PV,Kalinina EE,Pylaev AS

更新日期：2005-07-01 00:00:00

abstract：:The immunomodulatory properties of immunobiological drugs Glutoxim and Phosprenyl we well as vesicular stomatitis virus and inactivated tick-borne encephalitis vaccine virus were studied using human diploid fibroblast cell line from the collection of M. P. Chumakov Federal Research Center for Research and Development ...

journal_title：Bulletin of experimental biology and medicine

authors： Konyuschko OI,Ozherelkov SV,Vorovich MF,Ivanova AL,Sotskova SE,Ishmuhametov AA,Kozhevnikova TN,Sanin AV

更新日期：2020-12-01 00:00:00

abstract：:We studied the effects of blockade of nicotinic receptors in sympathetic and parasympathetic ganglia (hexamethonium), muscarinic receptors (atropine), and beta1-adrenoceptors (atenolol) on arrhythmogenic activity of endothelin-1 during inhibition of nitric oxide synthesis with Nomega-nitro-L-arginine in NMRI mice. Atr...

journal_title：Bulletin of experimental biology and medicine

authors： Lobanov AV,Rzhevskii DI,Korshunov VA,Murashev AN

更新日期：2004-02-01 00:00:00

abstract：:Changes in heart rate and stroke volume after successive blockade of cardiac adreno- and cholinoceptors were examined on rats of different age. It was established that irrespective of animal age the heart rate remained unchanged under conditions of total adreno- and cholinergic blockade of the heart. Stroke volume und...

journal_title：Bulletin of experimental biology and medicine

authors： Abzalov NI,Ziyatdinova AI,Abzalov RR

更新日期：2006-07-01 00:00:00

abstract：:Transplantation of human bone marrow mesenchymal stem cells is considered as a promising therapeutic approach to the therapy of many diseases. However, the problem of possible alterations of the properties of mesenchymal stem cells during their expansion in in vitro cultures before transplantation is not solved. In ou...

journal_title：Bulletin of experimental biology and medicine

authors： Grigorian AS,Kruglyakov PV,Taminkina UA,Efimova OA,Pendina AA,Voskresenskaya AV,Kuznetsova TV,Polyntsev DG

更新日期：2010-12-01 00:00:00

abstract：:We studied the effects of neurotensin dipeptide analog Dilept (N-caproyl-L-prolyl-L-tyrosine methyl ester) on dopamine metabolism and synthesis in the nucleus accumbens of Wistar rats. Dilept increased the levels of dopamine and its metabolites (homovanillic acid and dioxyphenylalanine) and stimulated dopamine turnove...

journal_title：Bulletin of experimental biology and medicine

authors： Shubenina EV,Kudrin VS,Klodt PM,Narkevich VB,Kuznetsova EA,Gudasheva TA,Ostrovskaya RU

更新日期：2012-09-01 00:00:00

abstract：:Alofanib is a potential allosteric inhibitor of FGFR2 used in oncology. The inhibitor blocks the extracellular part of the receptor and prevents its binding with the ligand. Alofanib suppressed proliferation of endothelial cells, their migration activity, and ability to form vessellike structures in vitro and signific...

journal_title：Bulletin of experimental biology and medicine

authors： Khochenkov DA,Solomko ES,Peretolchina NM,Ryabaya OO,Stepanova EV

更新日期：2015-11-01 00:00:00

abstract：:Comparative identification of cerebral regions activated in men and women during perception of indefinite images was carried out by fMRT and psychological testing. Nine men and nine women aged 20-26 years took part in the study. The volunteers examined simple geometric figures, slightly structurized images (tables fro...

journal_title：Bulletin of experimental biology and medicine

authors： Fyodorov AA,Pervushina ON,Bliznyuk MV,Khoroshilov BM,Melnikov ME,Mazhirina KG,Stark MB,Savelov AA,Petrovsky ED,Kozlova LI

更新日期：2016-07-01 00:00:00

abstract：:We studied the effect of leukemia-inhibiting factor on bilayer lipid membranes. Leukemia-inhibiting factor in a concentration of 10 ng/ml nonspecifically increased membrane permeability for ions. Leukemia-inhibiting factor acts as a surface-active substance on bilayer lipid membranes. ...

journal_title：Bulletin of experimental biology and medicine

authors： Serysheva VV,Borisova MP,Mezhevikina LM,Poltavtseva RA,Sukhkih GT

更新日期：2002-12-01 00:00:00

abstract：:A stable preparation of agaricinic acid nanoparticles was obtained. The mean hydrodynamic size of nanoparticles according to photon correlation spectroscopy was 200 nm and zeta potential was -57 mV. Cytotoxic activity of agaricinic acid nanoparticles against human HepG2 hepatoma cells was evaluated. Nanoparticles with...

journal_title：Bulletin of experimental biology and medicine

authors： Gudkova OI,Demchenko AG,Shvets AV,Kuryakov VN,Sedyakina NE,Lyundup AV,Feldman NB,Gromovykh TI,Lutsenko SV

更新日期：2020-08-01 00:00:00

abstract：:The fate of human fetal stem/progenitor cells transplanted into rat brain depends on conditions of preculturing (long or short) and state and site of transplantation. Human nestin-positive stem cells cultured according to the short protocol did not migrate into hypoxic and normal brain after transplantation, but activ...

journal_title：Bulletin of experimental biology and medicine

authors： Revishchin AV,Aleksandrova MA,Podgornyi OV,Marei MV,Poltavtseva RA,Korochkin LI,Stepanov GA,Sukhikh GT

更新日期：2005-02-01 00:00:00

abstract：:We compared analgesic activities of individual alkaloids extracted from Baikal aconite (Aconitum baikalensis): napelline, hypaconitine, songorine, mesaconitine, 12-epinapelline N-oxide. The detected analgesic activity was comparable to that of sodium metamizole. The mechanisms of analgesia were different in diterpene ...

journal_title：Bulletin of experimental biology and medicine

authors： Nesterova YV,Povet'yeva TN,Suslov NI,Zyuz'kov GN,Pushkarskii SV,Aksinenko SG,Schultz EE,Kravtsova SS,Krapivin AV

更新日期：2014-08-01 00:00:00

abstract：:Location of cathepsin D and elastase in rat uterus was studied by electron-histochemical method. Activities of both proteinases in the myometrium was detected in lysosomes of smooth-muscle cells, macrophages, and fibroblasts. ...

journal_title：Bulletin of experimental biology and medicine

authors： Ryvnyak VV,Gudumak VS,Dulgieru OF

更新日期：2003-08-01 00:00:00

abstract：:Anaferon (pediatric formulation) administered in the therapeutic-and-prophylactic regimen to mice receiving intranasally 100% infecting dose of A/California/07/2009(H1N1)v influenza virus exhibited an antiviral effect and 10-fold reduced the production of influenza virus in the lungs of infected mice on days 4, 6, and...

journal_title：Bulletin of experimental biology and medicine

authors： Shishkina LN,Skarnovich MO,Kabanov AS,Sergeev AA,Olkin SE,Tarasov SA,Belopolskaya MV,Sergeeva SA,Epstein OI,Malkova EM,Stavsky EA,Drozdov IG

更新日期：2010-10-01 00:00:00