Abstract:
:The effects of a new thietanylbenzimidazole derivative (K-134) on estrous cycles, conception processes, and sexual behavior of female rats were studied. Two-week oral treatment with K-134 in doses of 5 and 50 mg/kg shortened the estrus phase and prolonged proestrus. Changes in sexual behavior were presented by activation of receptive sexual motivations without affecting proceptive motivations. The pregnancy and fertility indexes in experimental females after mating with intact males increased and pre- and postimplantation embryonic death decreased.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Kuzubova EA,Bugaeva LI,Sergeeva SA,Petrov VI,Kataev VA,Kharlamov IV,Mal'tsev MVdoi
10.1007/s10517-015-3034-2subject
Has Abstractpub_date
2015-09-01 00:00:00pages
635-7issue
5eissn
0007-4888issn
1573-8221pii
10.1007/s10517-015-3034-2journal_volume
159pub_type
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